STRINGSTRING
LOC105806981 LOC105806981 RPA1 RPA1 TCEA3 TCEA3 MEIOB MEIOB HMGN2 HMGN2 ENSPCOP00000002346 ENSPCOP00000002346 ENSPCOP00000003049 ENSPCOP00000003049 LOC105820322 LOC105820322 LOC105809598 LOC105809598 XAB2 XAB2 ENSPCOP00000004338 ENSPCOP00000004338 LOC105813235 LOC105813235 UBA52 UBA52 ERCC4 ERCC4 TCEANC2 TCEANC2 ENSPCOP00000005034 ENSPCOP00000005034 PRPF19 PRPF19 ENSPCOP00000005978 ENSPCOP00000005978 LOC105809597 LOC105809597 ERCC6 ERCC6 POLR2E POLR2E LOC105812335 LOC105812335 DDB1 DDB1 ENSPCOP00000008190 ENSPCOP00000008190 PCNA PCNA BIVM BIVM ERCC2 ERCC2 GTF2H1 GTF2H1 RBX1 RBX1 POLE4 POLE4 TCEA2 TCEA2 POLR2C POLR2C HMGN1 HMGN1 ATAD5 ATAD5 ENSPCOP00000012718 ENSPCOP00000012718 POLR2I POLR2I CUL4B CUL4B POLE POLE USP40 USP40 POLD1 POLD1 ENSPCOP00000015216 ENSPCOP00000015216 MNAT1 MNAT1 ERCC8 ERCC8 RFC3 RFC3 RPS27A RPS27A ENSPCOP00000016400 ENSPCOP00000016400 XPA XPA RFC4 RFC4 RFC5 RFC5 POLR2H POLR2H ENSPCOP00000018904 ENSPCOP00000018904 AQR AQR LOC105824103 LOC105824103 TCEA1 TCEA1 EP300 EP300 PHF3 PHF3 RCBTB2 RCBTB2 ENSPCOP00000019919 ENSPCOP00000019919 POLR2D POLR2D GTF2H4 GTF2H4 RPA3 RPA3 CUL4A CUL4A RCBTB1 RCBTB1 SPOCD1 SPOCD1 POLD4 POLD4 ENSPCOP00000023542 ENSPCOP00000023542 POLD2 POLD2 POLR2G POLR2G POLD3 POLD3 POLR2J POLR2J NRDE2 NRDE2 ERCC3 ERCC3 LOC105819703 LOC105819703 POLR2A POLR2A POLR2F POLR2F ENSPCOP00000026727 ENSPCOP00000026727 LOC105816759 LOC105816759 RFC1 RFC1 ENSPCOP00000028431 ENSPCOP00000028431 LOC105807718 LOC105807718 UVSSA UVSSA ENSPCOP00000028633 ENSPCOP00000028633 RFC2 RFC2 GTF2H5 GTF2H5 POLE2 POLE2 POLE3 POLE3 POLK POLK USP7 USP7 ENSPCOP00000031025 ENSPCOP00000031025 CDK7 CDK7 ERCC1 ERCC1 LOC105823602 LOC105823602
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC105806981Uncharacterized protein. (257 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
TCEA3Transcription elongation factor A3. (348 aa)
MEIOBMeiosis specific with OB-fold. (289 aa)
HMGN2High mobility group nucleosomal binding domain 2. (90 aa)
ENSPCOP00000002346Uncharacterized protein. (58 aa)
ENSPCOP00000003049Uncharacterized protein. (437 aa)
LOC105820322Ubiquitin-like domain-containing protein. (77 aa)
LOC105809598Uncharacterized protein. (71 aa)
XAB2XPA binding protein 2. (855 aa)
ENSPCOP00000004338Uncharacterized protein. (69 aa)
LOC105813235Uncharacterized protein. (101 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (879 aa)
TCEANC2Transcription elongation factor A N-terminal and central domain containing 2. (162 aa)
ENSPCOP00000005034Uncharacterized protein. (90 aa)
PRPF19Pre-mRNA processing factor 19. (472 aa)
ENSPCOP00000005978Ssl1 domain-containing protein. (132 aa)
LOC105809597General transcription factor IIH subunit 5 pseudogene. (71 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1488 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
LOC105812335Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (250 aa)
DDB1Damage specific DNA binding protein 1. (1142 aa)
ENSPCOP00000008190AAA domain-containing protein. (331 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
BIVMUncharacterized protein. (1464 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (681 aa)
GTF2H1General transcription factor IIH subunit 1. (546 aa)
RBX1Ring-box 1. (108 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (118 aa)
TCEA2Transcription elongation factor A2. (300 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
HMGN1Uncharacterized protein. (102 aa)
ATAD5ATPase family AAA domain containing 5. (1646 aa)
ENSPCOP00000012718Ubiquitin-like domain-containing protein. (74 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
CUL4BCullin 4B; Belongs to the cullin family. (509 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2284 aa)
USP40Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. (1215 aa)
POLD1DNA polymerase. (1125 aa)
ENSPCOP00000015216Uncharacterized protein. (68 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (396 aa)
RFC3Replication factor C subunit 3. (356 aa)
RPS27ARibosomal protein S27a. (156 aa)
ENSPCOP00000016400Uncharacterized protein. (130 aa)
XPAXPA, DNA damage recognition and repair factor. (251 aa)
RFC4Replication factor C subunit 4. (365 aa)
RFC5AAA domain-containing protein. (338 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
ENSPCOP00000018904Ubiquitin-like domain-containing protein. (131 aa)
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1357 aa)
LOC105824103Uncharacterized protein. (430 aa)
TCEA1Transcription elongation factor A1. (301 aa)
EP300E1A binding protein p300. (2424 aa)
PHF3PHD finger protein 3. (1986 aa)
RCBTB2RCC1 and BTB domain containing protein 2. (551 aa)
ENSPCOP00000019919Uncharacterized protein. (102 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (463 aa)
RPA3Replication protein A3. (107 aa)
CUL4ACullin 4A; Belongs to the cullin family. (671 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
SPOCD1SPOC domain containing 1. (1198 aa)
POLD4Uncharacterized protein. (107 aa)
ENSPCOP00000023542Ubiquitin-like domain-containing protein. (112 aa)
POLD2DNA polymerase delta 2, accessory subunit. (504 aa)
POLR2GRNA polymerase II subunit G. (178 aa)
POLD3DNA polymerase delta 3, accessory subunit. (359 aa)
POLR2JRNA_pol_L_2 domain-containing protein. (141 aa)
NRDE2NRDE-2, necessary for RNA interference, domain containing. (1099 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
LOC105819703Uncharacterized protein. (195 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1978 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
ENSPCOP00000026727Uncharacterized protein. (84 aa)
LOC105816759Ubiquitin-like domain-containing protein. (156 aa)
RFC1Replication factor C subunit 1. (1113 aa)
ENSPCOP00000028431Protein kinase domain-containing protein. (287 aa)
LOC105807718General transcription factor IIH subunit. (385 aa)
UVSSAUV stimulated scaffold protein A. (497 aa)
ENSPCOP00000028633Uncharacterized protein. (58 aa)
RFC2Replication factor C subunit 2. (352 aa)
GTF2H5Uncharacterized protein. (71 aa)
POLE2DNA polymerase epsilon 2, accessory subunit. (439 aa)
POLE3DNA polymerase epsilon 3, accessory subunit. (147 aa)
POLKDNA polymerase kappa. (832 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1111 aa)
ENSPCOP00000031025Uncharacterized protein. (84 aa)
CDK7Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (289 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (298 aa)
LOC105823602Uncharacterized protein. (95 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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