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RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa) | ||||
MEIOB | Meiosis specific with OB-fold. (289 aa) | ||||
PRIM2 | Uncharacterized protein. (158 aa) | ||||
FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) | ||||
LIG1 | DNA ligase. (916 aa) | ||||
PRIM1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (420 aa) | ||||
DNA2 | Uncharacterized protein. (833 aa) | ||||
ENSPCOP00000024841 | Uncharacterized protein. (84 aa) | ||||
PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) | ||||
POLA1 | DNA polymerase. (1442 aa) | ||||
POLD1 | DNA polymerase. (1125 aa) | ||||
POLA2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (599 aa) | ||||
LOC105824103 | Uncharacterized protein. (430 aa) | ||||
RPA3 | Replication protein A3. (107 aa) | ||||
POLD4 | Uncharacterized protein. (107 aa) | ||||
POLD2 | DNA polymerase delta 2, accessory subunit. (504 aa) | ||||
POLD3 | DNA polymerase delta 3, accessory subunit. (359 aa) |