STRINGSTRING
YAP1 YAP1 GLI3 GLI3 ENSPCOP00000000722 ENSPCOP00000000722 ZNF521 ZNF521 HDAC3 HDAC3 HEY1 HEY1 SP8 SP8 ZNF423 ZNF423 SP7 SP7 HES1 HES1 MAPK3 MAPK3 UCMA UCMA RB1 RB1 SP9 SP9 BGLAP BGLAP MAF MAF SRC SRC WWTR1 WWTR1 COL1A1 COL1A1 ENSPCOP00000022031 ENSPCOP00000022031 HES4 HES4 ENSPCOP00000025005 ENSPCOP00000025005 CBFB CBFB HDAC6 HDAC6 MAPK1 MAPK1 HEY2 HEY2 AR AR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
YAP1Uncharacterized protein. (504 aa)
GLI3GLI family zinc finger 3. (1580 aa)
ENSPCOP00000000722Protein kinase domain-containing protein. (67 aa)
ZNF521Zinc finger protein 521. (1326 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (308 aa)
SP8Sp8 transcription factor. (506 aa)
ZNF423Zinc finger protein 423. (1192 aa)
SP7Sp7 transcription factor. (431 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
UCMAUpper zone of growth plate and cartilage matrix associated. (84 aa)
RB1RB transcriptional corepressor 1. (787 aa)
SP9Sp9 transcription factor. (487 aa)
BGLAPOsteocalcin; Binds strongly to apatite and calcium. (102 aa)
MAFMAF bZIP transcription factor. (242 aa)
SRCTyrosine-protein kinase. (543 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
COL1A1Collagen type I alpha 1 chain. (1461 aa)
ENSPCOP00000022031Uncharacterized protein. (95 aa)
HES4Hes family bHLH transcription factor 4. (239 aa)
ENSPCOP00000025005Uncharacterized protein. (351 aa)
CBFBCore-binding factor subunit beta. (187 aa)
HDAC6Histone deacetylase 6. (1203 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
ARAndrogen receptor. (886 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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