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RUNX3 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (433 aa) | ||||
TCF7L2 | Transcription factor 7 like 2. (619 aa) | ||||
LEF1 | Lymphoid enhancer binding factor 1. (432 aa) | ||||
MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (453 aa) | ||||
TCF7 | Transcription factor 7. (303 aa) | ||||
TCF7L1 | Transcription factor 7 like 1. (590 aa) | ||||
CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) | ||||
CTNNB1 | Catenin beta 1. (781 aa) |