21 items (Propithecus coquereli) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	FRS2	Fibroblast growth factor receptor substrate 2. (508 aa)
	SHC1	SHC adaptor protein 1. (582 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	TIAM1	T cell lymphoma invasion and metastasis 1. (1590 aa)
	GRIN2B	Glutamate ionotropic receptor NMDA type subunit 2B. (1485 aa)
	CDK5	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	KRAS	Uncharacterized protein. (75 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
	CDK5R1	Cyclin-dependent kinase 5 activator. (306 aa)
	NTRK2	Tyrosine-protein kinase receptor. (838 aa)
	BDNF	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (329 aa)
	FRS3	Fibroblast growth factor receptor substrate 3. (492 aa)
	NRAS	NRAS proto-oncogene, GTPase. (189 aa)
	DOCK3	Dedicator of cytokinesis 3; Belongs to the DOCK family. (1899 aa)
	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1304 aa)
	PIK3CA	Phosphatidylinositol 3-kinase catalytic subunit type 3. (933 aa)
	GRB2	Growth factor receptor bound protein 2. (217 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
	SRC	Tyrosine-protein kinase. (543 aa)
	HRAS	HRas proto-oncogene, GTPase. (189 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDNF	CDK5	ENSPCOP00000001515	ENSPCOP00000026355	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	0.633
BDNF	DOCK3	ENSPCOP00000001515	ENSPCOP00000026144	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Dedicator of cytokinesis 3; Belongs to the DOCK family.	0.684
BDNF	FRS2	ENSPCOP00000001515	ENSPCOP00000019145	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Fibroblast growth factor receptor substrate 2.	0.721
BDNF	FRS3	ENSPCOP00000001515	ENSPCOP00000003508	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Fibroblast growth factor receptor substrate 3.	0.658
BDNF	FYN	ENSPCOP00000001515	ENSPCOP00000008529	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Tyrosine-protein kinase.	0.783
BDNF	GRB2	ENSPCOP00000001515	ENSPCOP00000017791	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Growth factor receptor bound protein 2.	0.737
BDNF	GRIN2B	ENSPCOP00000001515	ENSPCOP00000026802	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Glutamate ionotropic receptor NMDA type subunit 2B.	0.690
BDNF	NTRK2	ENSPCOP00000001515	ENSPCOP00000001158	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Tyrosine-protein kinase receptor.	0.977
BDNF	PLCG1	ENSPCOP00000001515	ENSPCOP00000024732	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.692
BDNF	SHC1	ENSPCOP00000001515	ENSPCOP00000031654	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	SHC adaptor protein 1.	0.560
BDNF	SOS1	ENSPCOP00000001515	ENSPCOP00000009149	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	SOS Ras/Rac guanine nucleotide exchange factor 1.	0.674
BDNF	SRC	ENSPCOP00000001515	ENSPCOP00000018583	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Tyrosine-protein kinase.	0.679
BDNF	TIAM1	ENSPCOP00000001515	ENSPCOP00000027967	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	T cell lymphoma invasion and metastasis 1.	0.513
CDK5	BDNF	ENSPCOP00000026355	ENSPCOP00000001515	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	0.633
CDK5	CDK5R1	ENSPCOP00000026355	ENSPCOP00000000683	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	Cyclin-dependent kinase 5 activator.	0.999
CDK5	FYN	ENSPCOP00000026355	ENSPCOP00000008529	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.892
CDK5	GRIN2B	ENSPCOP00000026355	ENSPCOP00000026802	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	Glutamate ionotropic receptor NMDA type subunit 2B.	0.439
CDK5	NTRK2	ENSPCOP00000026355	ENSPCOP00000001158	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase receptor.	0.493
CDK5	SRC	ENSPCOP00000026355	ENSPCOP00000018583	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.621
CDK5R1	CDK5	ENSPCOP00000000683	ENSPCOP00000026355	Cyclin-dependent kinase 5 activator.	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	0.999