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MYO5A MYO5A WAS WAS CYFIP2 CYFIP2 ELMO2 ELMO2 LOC105810942 LOC105810942 MAPK1 MAPK1 BTK BTK ELMO1 ELMO1 ENSPCOP00000027946 ENSPCOP00000027946 WIPF2 WIPF2 ACTR2 ACTR2 PTK2 PTK2 LYN LYN WASL WASL ACTR3 ACTR3 ARPC5 ARPC5 CDC42 CDC42 ACTG1 ACTG1 BAIAP2 BAIAP2 VAV3 VAV3 ENSPCOP00000000722 ENSPCOP00000000722 ENSPCOP00000000994 ENSPCOP00000000994 ARPC2 ARPC2 NCK1 NCK1 NCKAP1 NCKAP1 NCKIPSD NCKIPSD ENSPCOP00000002927 ENSPCOP00000002927 ARPC1B ARPC1B WASF1 WASF1 MYH9 MYH9 ENSPCOP00000004655 ENSPCOP00000004655 ACTB ACTB ARPC1A ARPC1A MYO10 MYO10 WIPF3 WIPF3 CYFIP1 CYFIP1 VAV2 VAV2 ABI1 ABI1 MAPK3 MAPK3 FYN FYN WIPF1 WIPF1 SYK SYK ARPC3 ARPC3 HCK HCK MYO9B MYO9B WASF2 WASF2 VAV1 VAV1 MYO1C MYO1C CD247 CD247 WASF3 WASF3 CD3G CD3G BRK1 BRK1 GRB2 GRB2 CRK CRK FGR FGR SRC SRC NCKAP1L NCKAP1L LOC105811778 LOC105811778
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MYO5AMyosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1862 aa)
WASWASP actin nucleation promoting factor. (503 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
ELMO2Engulfment and cell motility 2. (720 aa)
LOC105810942WD_REPEATS_REGION domain-containing protein. (347 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
BTKTyrosine-protein kinase. (647 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
ENSPCOP00000027946Uncharacterized protein. (298 aa)
WIPF2WAS/WASL interacting protein family member 2. (440 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
PTK2Protein tyrosine kinase 2. (1089 aa)
LYNTyrosine-protein kinase. (512 aa)
WASLWASP like actin nucleation promoting factor. (505 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (418 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (126 aa)
CDC42Uncharacterized protein. (191 aa)
ACTG1Actin gamma 1. (404 aa)
BAIAP2BAI1 associated protein 2. (544 aa)
VAV3Vav guanine nucleotide exchange factor 3. (765 aa)
ENSPCOP00000000722Protein kinase domain-containing protein. (67 aa)
ENSPCOP00000000994Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (173 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (292 aa)
NCK1Cytoplasmic protein. (377 aa)
NCKAP1NCK associated protein 1. (1006 aa)
NCKIPSDNCK interacting protein with SH3 domain. (714 aa)
ENSPCOP00000002927Uncharacterized protein. (160 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (372 aa)
WASF1WASP family member 1. (559 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1967 aa)
ENSPCOP00000004655WD_REPEATS_REGION domain-containing protein. (262 aa)
ACTBActin beta. (378 aa)
ARPC1AUncharacterized protein. (188 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2080 aa)
WIPF3WAS/WASL interacting protein family member 3. (394 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1244 aa)
VAV2Vav guanine nucleotide exchange factor 2. (771 aa)
ABI1Abl interactor 1. (508 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
FYNTyrosine-protein kinase. (537 aa)
WIPF1WH2 domain-containing protein. (509 aa)
SYKSpleen associated tyrosine kinase. (637 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
HCKTyrosine-protein kinase. (524 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2159 aa)
WASF2WASP family member 2. (497 aa)
VAV1Vav guanine nucleotide exchange factor 1. (806 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1063 aa)
CD247CD247 molecule. (164 aa)
WASF3WASP family member 3. (485 aa)
CD3GCD3g molecule. (182 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
FGRTyrosine-protein kinase. (495 aa)
SRCTyrosine-protein kinase. (543 aa)
NCKAP1LNCK associated protein 1 like. (1138 aa)
LOC105811778WD_REPEATS_REGION domain-containing protein. (354 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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