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AHCYL2 AHCYL2 FTCDNL1 FTCDNL1 GCLC GCLC HSD17B14 HSD17B14 SCUBE3 SCUBE3 MRI1 MRI1 SDS SDS ENSPCOP00000020173 ENSPCOP00000020173 BCAT2 BCAT2 MDH2 MDH2 MDH1 MDH1 URB2 URB2 LDHB LDHB MAT1A MAT1A CDO1 CDO1 GOT2 GOT2 AHCYL1 AHCYL1 KYAT1 KYAT1 AMD1 AMD1 DNMT3A DNMT3A DNMT3B DNMT3B ENSPCOP00000026464 ENSPCOP00000026464 ENSPCOP00000026694 ENSPCOP00000026694 ENSPCOP00000027005 ENSPCOP00000027005 GSS GSS TSTD3 TSTD3 SRFBP1 SRFBP1 GOT1L1 GOT1L1 LTO1 LTO1 GOT1 GOT1 ENSPCOP00000031755 ENSPCOP00000031755 TFB1M TFB1M AHCY AHCY SDSL SDSL TAT TAT MPST MPST MTR MTR SCUBE1 SCUBE1 MFSD11 MFSD11 TSTD1 TSTD1 ENSPCOP00000001921 ENSPCOP00000001921 KYAT3 KYAT3 ENSPCOP00000003497 ENSPCOP00000003497 ENSPCOP00000003860 ENSPCOP00000003860 ENSPCOP00000004635 ENSPCOP00000004635 MAT2A MAT2A AGXT2 AGXT2 BHMT2 BHMT2 IL4I1 IL4I1 ADI1 ADI1 SRM SRM ENOPH1 ENOPH1 PHGDH PHGDH GCLM GCLM BHMT BHMT APIP APIP TRDMT1 TRDMT1 SCUBE2 SCUBE2 LOC105822434 LOC105822434 PSAT1 PSAT1 TST TST ENSPCOP00000009899 ENSPCOP00000009899 ENSPCOP00000009939 ENSPCOP00000009939 ACCS ACCS MDH1B MDH1B MTAP MTAP SMS SMS LOC105817330 LOC105817330 TFB2M TFB2M DIMT1 DIMT1 RNF138 RNF138 DNMT1 DNMT1 CBS CBS BCAT1 BCAT1 VBP1 VBP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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AHCYL2Adenosylhomocysteinase like 2. (477 aa)
FTCDNL1Formiminotransferase cyclodeaminase N-terminal like. (146 aa)
GCLCGlutamate-cysteine ligase catalytic subunit. (637 aa)
HSD17B14Hydroxysteroid 17-beta dehydrogenase 14. (270 aa)
SCUBE3Signal peptide, CUB domain and EGF like domain containing 3. (993 aa)
MRI1Methylthioribose-1-phosphate isomerase 1; Belongs to the eIF-2B alpha/beta/delta subunits family. (325 aa)
SDSSerine dehydratase. (328 aa)
ENSPCOP00000020173Ldh_1_C domain-containing protein. (58 aa)
BCAT2Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (424 aa)
MDH2Malate dehydrogenase. (338 aa)
MDH1Malate dehydrogenase. (352 aa)
URB2URB2 ribosome biogenesis homolog. (1524 aa)
LDHBLdh_1_N domain-containing protein. (252 aa)
MAT1AS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (396 aa)
CDO1Cysteine dioxygenase. (200 aa)
GOT2Aspartate aminotransferase. (370 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
KYAT1Aminotran_1_2 domain-containing protein. (515 aa)
AMD1S-adenosylmethionine decarboxylase proenzyme. (334 aa)
DNMT3ADNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (912 aa)
DNMT3BDNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (855 aa)
ENSPCOP00000026464Uncharacterized protein. (46 aa)
ENSPCOP00000026694Uncharacterized protein; Belongs to the LDH/MDH superfamily. (269 aa)
ENSPCOP00000027005C2HC RNF-type domain-containing protein. (215 aa)
GSSGlutathione synthetase. (474 aa)
TSTD3Thiosulfate sulfurtransferase like domain containing 3. (112 aa)
SRFBP1Serum response factor binding protein 1. (429 aa)
GOT1L1Glutamic-oxaloacetic transaminase 1 like 1. (409 aa)
LTO1LTO1 maturation factor of ABCE1. (137 aa)
GOT1Aspartate aminotransferase. (413 aa)
ENSPCOP00000031755Uncharacterized protein; Belongs to the LDH/MDH superfamily. (324 aa)
TFB1MrRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (345 aa)
AHCYAdenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. (436 aa)
SDSLSerine dehydratase like. (268 aa)
TATTyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (454 aa)
MPSTMercaptopyruvate sulfurtransferase. (333 aa)
MTRMethionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1265 aa)
SCUBE1Signal peptide, CUB domain and EGF like domain containing 1. (988 aa)
MFSD11Major facilitator superfamily domain containing 11. (449 aa)
TSTD1Thiosulfate sulfurtransferase like domain containing 1. (115 aa)
ENSPCOP00000001921L-lactate dehydrogenase. (273 aa)
KYAT3Kynurenine aminotransferase 3. (420 aa)
ENSPCOP00000003497Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. (104 aa)
ENSPCOP00000003860Ldh_1_C domain-containing protein. (87 aa)
ENSPCOP00000004635L-lactate dehydrogenase. (233 aa)
MAT2AS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (395 aa)
AGXT2Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (484 aa)
BHMT2Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism. (363 aa)
IL4I1Amine oxidase. (582 aa)
ADI11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (179 aa)
SRMSpermidine synthase; Belongs to the spermidine/spermine synthase family. (302 aa)
ENOPH1Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (261 aa)
PHGDHD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
GCLMGlutamate-cysteine ligase modifier subunit. (274 aa)
BHMTBetaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism. (407 aa)
APIPMethylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. (242 aa)
TRDMT1tRNA aspartic acid methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (370 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (994 aa)
LOC105822434PABS domain-containing protein. (366 aa)
PSAT1Phosphoserine aminotransferase. (370 aa)
TSTSulfurtransferase. (297 aa)
ENSPCOP00000009899L-lactate dehydrogenase. (243 aa)
ENSPCOP00000009939Uncharacterized protein. (133 aa)
ACCS1-aminocyclopropane-1-carboxylate synthase homolog (inactive). (501 aa)
MDH1BMalate dehydrogenase 1B. (498 aa)
MTAPS-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (299 aa)
SMSPABS domain-containing protein. (368 aa)
LOC105817330L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (324 aa)
TFB2MrRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (379 aa)
DIMT1rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (313 aa)
RNF138Uncharacterized protein. (207 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1615 aa)
CBSCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (554 aa)
BCAT1Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (358 aa)
VBP1Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. (230 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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