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ADAMTS6 ADAMTS6 SPTLC3 SPTLC3 CERK CERK ASAH1 ASAH1 SMPD2 SMPD2 SGMS2 SGMS2 SPHK2 SPHK2 ASAH2 ASAH2 CERS5 CERS5 EEF1AKMT1 EEF1AKMT1 GLB1L2 GLB1L2 SEC14L3 SEC14L3 SGPP1 SGPP1 B4GALT6 B4GALT6 GAL3ST4 GAL3ST4 PSAP PSAP ADAMTSL3 ADAMTSL3 ACER3 ACER3 ADAMTS14 ADAMTS14 PLPP2 PLPP2 SMPD3 SMPD3 NEU3 NEU3 ENPP7 ENPP7 SGPL1 SGPL1 METTL22 METTL22 ADAMTS16 ADAMTS16 ENSPCOP00000007999 ENSPCOP00000007999 PLPP1 PLPP1 SMPD4 SMPD4 ENSPCOP00000008455 ENSPCOP00000008455 DEGS1 DEGS1 LOC105814642 LOC105814642 COPE COPE TCTN3 TCTN3 ARSA ARSA ACER1 ACER1 NEU1 NEU1 SEC14L1 SEC14L1 NEDD8 NEDD8 SPHK1 SPHK1 ADAMTS7 ADAMTS7 SGPP2 SGPP2 TCTN1 TCTN1 ADAMTS2 ADAMTS2 BOD1 BOD1 ENSPCOP00000012134 ENSPCOP00000012134 ADAMTS20 ADAMTS20 CLASRP CLASRP TM9SF3 TM9SF3 GAL3ST1 GAL3ST1 CERS4 CERS4 SPTLC1 SPTLC1 NAAA NAAA ADAMTS3 ADAMTS3 ADAMTSL1 ADAMTSL1 SAMD8 SAMD8 ADAMTS12 ADAMTS12 CERKL CERKL ISM1 ISM1 CERS3 CERS3 NEU4 NEU4 ENSPCOP00000015803 ENSPCOP00000015803 CERS6 CERS6 ACER2 ACER2 SEC14L4 SEC14L4 SEC14L5 SEC14L5 UGT8 UGT8 CERS2 CERS2 SEC14L2 SEC14L2 ADAMTS9 ADAMTS9 GLB1L GLB1L ADAMTS1 ADAMTS1 KDSR KDSR ADAMTSL2 ADAMTSL2 GLB1 GLB1 ENSPCOP00000022276 ENSPCOP00000022276 GLA GLA LYRM1 LYRM1 PLPP3 PLPP3 GALC GALC SMPD1 SMPD1 ERCC6L ERCC6L LINS1 LINS1 DEGS2 DEGS2 GBA2 GBA2 NEU2 NEU2 TMEM130 TMEM130 ADAMTS18 ADAMTS18 ADAMTS19 ADAMTS19 ADAMTS15 ADAMTS15 UGCG UGCG GAL3ST2 GAL3ST2 SMPDL3B SMPDL3B SGMS1 SGMS1 LOC105814424 LOC105814424 ADAMTS10 ADAMTS10 ENSPCOP00000029431 ENSPCOP00000029431 EEF2KMT EEF2KMT GAL3ST3 GAL3ST3 ADAMTS13 ADAMTS13 ADAMTS4 ADAMTS4 BOD1L1 BOD1L1 GBA GBA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADAMTS6ADAM metallopeptidase with thrombospondin type 1 motif 6. (1117 aa)
SPTLC3Serine palmitoyltransferase long chain base subunit 3. (552 aa)
CERKCeramide kinase. (537 aa)
ASAH1N-acylsphingosine amidohydrolase 1. (242 aa)
SMPD2Sphingomyelin phosphodiesterase 2. (423 aa)
SGMS2Sphingomyelin synthase 2. (366 aa)
SPHK2Sphingosine kinase 2. (660 aa)
ASAH2Neutral ceramidase. (726 aa)
CERS5Ceramide synthase 5. (392 aa)
EEF1AKMT1EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family. (214 aa)
GLB1L2Beta-galactosidase. (607 aa)
SEC14L3SEC14 like lipid binding 3. (400 aa)
SGPP1Sphingosine-1-phosphate phosphatase 1. (441 aa)
B4GALT6Beta-1,4-galactosyltransferase 6. (336 aa)
GAL3ST4Galactose-3-O-sulfotransferase 4. (481 aa)
PSAPProsaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. (523 aa)
ADAMTSL3ADAMTS like 3. (1691 aa)
ACER3Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (267 aa)
ADAMTS14ADAM metallopeptidase with thrombospondin type 1 motif 14. (1048 aa)
PLPP2Phospholipid phosphatase 2. (304 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (656 aa)
NEU3Neuraminidase 3. (462 aa)
ENPP7Ectonucleotide pyrophosphatase/phosphodiesterase 7. (450 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (560 aa)
METTL22Methyltransferase like 22. (348 aa)
ADAMTS16ADAM metallopeptidase with thrombospondin type 1 motif 16. (1209 aa)
ENSPCOP00000007999Uncharacterized protein. (107 aa)
PLPP1Phospholipid phosphatase 1. (286 aa)
SMPD4Uncharacterized protein. (864 aa)
ENSPCOP00000008455Uncharacterized protein. (400 aa)
DEGS1Delta 4-desaturase, sphingolipid 1. (323 aa)
LOC105814642UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (523 aa)
COPECoatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family. (322 aa)
TCTN3Tectonic family member 3. (605 aa)
ARSAArylsulfatase A. (423 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa)
NEU1Neuraminidase 1. (416 aa)
SEC14L1SEC14 like lipid binding 1. (722 aa)
NEDD8NEDD8 ubiquitin like modifier. (86 aa)
SPHK1Sphingosine kinase 1. (469 aa)
ADAMTS7ADAM metallopeptidase with thrombospondin type 1 motif 7. (1663 aa)
SGPP2Sphingosine-1-phosphate phosphatase 2. (390 aa)
TCTN1Tectonic family member 1. (587 aa)
ADAMTS2ADAM metallopeptidase with thrombospondin type 1 motif 2. (986 aa)
BOD1Uncharacterized protein. (199 aa)
ENSPCOP00000012134Glyco_hydro_35 domain-containing protein. (292 aa)
ADAMTS20ADAM metallopeptidase with thrombospondin type 1 motif 20. (1901 aa)
CLASRPCLK4 associating serine/arginine rich protein. (678 aa)
TM9SF3Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (629 aa)
GAL3ST1Galactose-3-O-sulfotransferase 1. (423 aa)
CERS4Ceramide synthase 4. (396 aa)
SPTLC1Serine palmitoyltransferase long chain base subunit 1. (455 aa)
NAAAN-acylethanolamine acid amidase; Belongs to the acid ceramidase family. (321 aa)
ADAMTS3ADAM metallopeptidase with thrombospondin type 1 motif 3. (1160 aa)
ADAMTSL1ADAMTS like 1. (1764 aa)
SAMD8Sterile alpha motif domain containing 8. (478 aa)
ADAMTS12ADAM metallopeptidase with thrombospondin type 1 motif 12. (1602 aa)
CERKLCeramide kinase like. (560 aa)
ISM1Isthmin 1. (463 aa)
CERS3Ceramide synthase 3. (349 aa)
NEU4Neuraminidase 4. (487 aa)
ENSPCOP00000015803Uncharacterized protein. (89 aa)
CERS6Ceramide synthase 6. (392 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
SEC14L4SEC14 like lipid binding 4. (406 aa)
SEC14L5SEC14 like lipid binding 5. (638 aa)
UGT8UDP glycosyltransferase 8. (474 aa)
CERS2Ceramide synthase 2. (411 aa)
SEC14L2Uncharacterized protein. (403 aa)
ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif 9. (1838 aa)
GLB1LGalactosidase beta 1 like; Belongs to the glycosyl hydrolase 35 family. (651 aa)
ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif 1. (965 aa)
KDSR3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (332 aa)
ADAMTSL2ADAMTS like 2. (1052 aa)
GLB1Beta-galactosidase. (640 aa)
ENSPCOP00000022276Peptidase M12B domain-containing protein. (545 aa)
GLAAlpha-galactosidase. (428 aa)
LYRM1LYR motif containing 1; Belongs to the complex I LYR family. (122 aa)
PLPP3acidPPc domain-containing protein. (312 aa)
GALCGalactosylceramidase. (642 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa)
ERCC6LERCC excision repair 6 like, spindle assembly checkpoint helicase. (1251 aa)
LINS1Lines homolog 1. (758 aa)
DEGS2Delta 4-desaturase, sphingolipid 2. (323 aa)
GBA2Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (927 aa)
NEU2Neuraminidase 2. (379 aa)
TMEM130Transmembrane protein 130. (423 aa)
ADAMTS18ADAM metallopeptidase with thrombospondin type 1 motif 18. (1115 aa)
ADAMTS19ADAM metallopeptidase with thrombospondin type 1 motif 19. (1215 aa)
ADAMTS15ADAM metallopeptidase with thrombospondin type 1 motif 15. (950 aa)
UGCGUDP-glucose ceramide glucosyltransferase. (360 aa)
GAL3ST2Galactose-3-O-sulfotransferase 2. (401 aa)
SMPDL3BAcid sphingomyelinase-like phosphodiesterase. (458 aa)
SGMS1Sphingomyelin synthase 1. (419 aa)
LOC105814424UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (523 aa)
ADAMTS10ADAM metallopeptidase with thrombospondin type 1 motif 10. (1103 aa)
ENSPCOP00000029431Saposin B-type domain-containing protein. (129 aa)
EEF2KMTUncharacterized protein. (298 aa)
GAL3ST3Galactose-3-O-sulfotransferase 3. (431 aa)
ADAMTS13ADAM metallopeptidase with thrombospondin type 1 motif 13. (1355 aa)
ADAMTS4ADAM metallopeptidase with thrombospondin type 1 motif 4. (837 aa)
BOD1L1Biorientation of chromosomes in cell division 1 like 1. (3018 aa)
GBAGlucosylceramidase. (529 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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