STRINGSTRING
ENSPCOP00000003708 ENSPCOP00000003708 TM4SF19 TM4SF19 TOR1B TOR1B GDAP2 GDAP2 RNASEH2A RNASEH2A MEIOB MEIOB RPA1 RPA1 EXOC8 EXOC8 PARP14 PARP14 POLA2 POLA2 MCM6 MCM6 RNASEH1 RNASEH1 POLD1 POLD1 POLE POLE CPNE8 CPNE8 YJU2 YJU2 STN1 STN1 POLA1 POLA1 MCM2 MCM2 ATAD5 ATAD5 WRNIP1 WRNIP1 POLE4 POLE4 MCM9 MCM9 CPNE7 CPNE7 PCNA PCNA ENSPCOP00000008190 ENSPCOP00000008190 C16orf70 C16orf70 CPNE2 CPNE2 CPNE6 CPNE6 MCM3 MCM3 MCM4 MCM4 MCM5 MCM5 MCM7 MCM7 TOR2A TOR2A SASS6 SASS6 CPNE5 CPNE5 FEN1 FEN1 MCMDC2 MCMDC2 PPIL3 PPIL3 PRIM2 PRIM2 CABP5 CABP5 LIG1 LIG1 PRIM1 PRIM1 CPNE9 CPNE9 POLE3 POLE3 POLE2 POLE2 DNA2 DNA2 RFC2 RFC2 RNASEH2B RNASEH2B RFC1 RFC1 PARP15 PARP15 MACROD2 MACROD2 ENSPCOP00000024841 ENSPCOP00000024841 POLD3 POLD3 FAM162A FAM162A POLD2 POLD2 POLD4 POLD4 RPA2 RPA2 RAD17 RAD17 PARP9 PARP9 MACROD1 MACROD1 PRKRIP1 PRKRIP1 TOR3A TOR3A RPA3 RPA3 GEN1 GEN1 CPNE4 CPNE4 LOC105824103 LOC105824103 CHRAC1 CHRAC1 RNASEH2C RNASEH2C CPNE3 CPNE3 SSBP1 SSBP1 RFC5 RFC5 RFC4 RFC4 TOR1A TOR1A RFC3 RFC3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPCOP00000003708Uncharacterized protein. (135 aa)
TM4SF19Uncharacterized protein. (209 aa)
TOR1BTorsin. (336 aa)
GDAP2Ganglioside induced differentiation associated protein 2. (429 aa)
RNASEH2ARibonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (300 aa)
MEIOBMeiosis specific with OB-fold. (289 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
EXOC8Exocyst complex component 8. (728 aa)
PARP14Poly [ADP-ribose] polymerase. (1791 aa)
POLA2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (599 aa)
MCM6DNA helicase; Belongs to the MCM family. (821 aa)
RNASEH1Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (266 aa)
POLD1DNA polymerase. (1125 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2284 aa)
CPNE8Copine 8. (542 aa)
YJU2YJU2 splicing factor homolog. (325 aa)
STN1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (369 aa)
POLA1DNA polymerase. (1442 aa)
MCM2DNA helicase; Belongs to the MCM family. (738 aa)
ATAD5ATPase family AAA domain containing 5. (1646 aa)
WRNIP1WRN helicase interacting protein 1. (666 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (118 aa)
MCM9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1103 aa)
CPNE7Copine 7. (599 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
ENSPCOP00000008190AAA domain-containing protein. (331 aa)
C16orf70Chromosome 16 open reading frame 70. (433 aa)
CPNE2Copine 2. (548 aa)
CPNE6Copine 6. (608 aa)
MCM3DNA helicase; Belongs to the MCM family. (853 aa)
MCM4DNA helicase; Belongs to the MCM family. (863 aa)
MCM5DNA helicase; Belongs to the MCM family. (734 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa)
TOR2ATorsin. (321 aa)
SASS6SAS-6 centriolar assembly protein. (657 aa)
CPNE5Copine 5. (575 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
MCMDC2Minichromosome maintenance domain containing 2. (678 aa)
PPIL3Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (161 aa)
PRIM2Uncharacterized protein. (158 aa)
CABP5Calcium binding protein 5. (165 aa)
LIG1DNA ligase. (916 aa)
PRIM1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (420 aa)
CPNE9Copine family member 9. (553 aa)
POLE3DNA polymerase epsilon 3, accessory subunit. (147 aa)
POLE2DNA polymerase epsilon 2, accessory subunit. (439 aa)
DNA2Uncharacterized protein. (833 aa)
RFC2Replication factor C subunit 2. (352 aa)
RNASEH2BRibonuclease H2 subunit B. (309 aa)
RFC1Replication factor C subunit 1. (1113 aa)
PARP15Poly [ADP-ribose] polymerase. (667 aa)
MACROD2Mono-ADP ribosylhydrolase 2. (414 aa)
ENSPCOP00000024841Uncharacterized protein. (84 aa)
POLD3DNA polymerase delta 3, accessory subunit. (359 aa)
FAM162AFamily with sequence similarity 162 member A. (155 aa)
POLD2DNA polymerase delta 2, accessory subunit. (504 aa)
POLD4Uncharacterized protein. (107 aa)
RPA2Replication protein A2. (306 aa)
RAD17RAD17 checkpoint clamp loader component. (475 aa)
PARP9Poly(ADP-ribose) polymerase family member 9. (857 aa)
MACROD1Mono-ADP ribosylhydrolase 1. (325 aa)
PRKRIP1PRKR interacting protein 1. (187 aa)
TOR3ATorsin family 3 member A. (302 aa)
RPA3Replication protein A3. (107 aa)
GEN1GEN1 Holliday junction 5' flap endonuclease. (782 aa)
CPNE4Copine 4. (575 aa)
LOC105824103Uncharacterized protein. (430 aa)
CHRAC1Chromatin accessibility complex subunit 1. (133 aa)
RNASEH2CRibonuclease H2 subunit C. (164 aa)
CPNE3Copine 3. (478 aa)
SSBP1Single stranded DNA binding protein 1. (148 aa)
RFC5AAA domain-containing protein. (338 aa)
RFC4Replication factor C subunit 4. (365 aa)
TOR1ATorsin. (332 aa)
RFC3Replication factor C subunit 3. (356 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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