STRINGSTRING
SEPTIN4 SEPTIN4 NGFR NGFR BBC3 BBC3 BAK1 BAK1 APAF1 APAF1 CASP3 CASP3 CASP7 CASP7 BAX BAX BIRC5 BIRC5 BCL2L1 BCL2L1 BCL2 BCL2 BIRC2 BIRC2 FADD FADD MAPK10 MAPK10 HTRA2 HTRA2 ENSPCOP00000023228 ENSPCOP00000023228 ENSPCOP00000023440 ENSPCOP00000023440 CASP8 CASP8 ENSPCOP00000024116 ENSPCOP00000024116 BCL2L11 BCL2L11 SEPTIN4-2 SEPTIN4-2 DIABLO DIABLO ENSPCOP00000027105 ENSPCOP00000027105 LOC105807375 LOC105807375 TNFRSF1A TNFRSF1A MAPK8 MAPK8 BECN1 BECN1 CASP9 CASP9 LOC105815609 LOC105815609 BID BID MAPK9 MAPK9 PMAIP1 PMAIP1 BIRC3 BIRC3 BOK BOK BIRC6 BIRC6 ENSPCOP00000004684 ENSPCOP00000004684 ENSPCOP00000007435 ENSPCOP00000007435 TMEM198 TMEM198 BIRC7 BIRC7 XIAP XIAP C7orf31 C7orf31
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SEPTIN4Septin 4. (560 aa)
NGFRNerve growth factor receptor. (429 aa)
BBC3BCL2 binding component 3. (260 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
APAF1Apoptotic peptidase activating factor 1. (1204 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (341 aa)
BAXBCL2 associated X, apoptosis regulator. (199 aa)
BIRC5Baculoviral IAP repeat containing 5. (142 aa)
BCL2L1BCL2 like 1. (233 aa)
BCL2BCL2 apoptosis regulator. (234 aa)
BIRC2Baculoviral IAP repeat containing 2. (619 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (205 aa)
MAPK10Mitogen-activated protein kinase. (473 aa)
HTRA2HtrA serine peptidase 2. (458 aa)
ENSPCOP00000023228Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (99 aa)
ENSPCOP00000023440Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (95 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (395 aa)
ENSPCOP00000024116Uncharacterized protein. (120 aa)
BCL2L11BCL2 like 11. (200 aa)
SEPTIN4-2Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (494 aa)
DIABLOUncharacterized protein. (168 aa)
ENSPCOP00000027105Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC105807375Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
TNFRSF1ATNF receptor superfamily member 1A. (447 aa)
MAPK8Mitogen-activated protein kinase 8. (346 aa)
BECN1Beclin 1. (448 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (406 aa)
LOC105815609Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (100 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (220 aa)
MAPK9Mitogen-activated protein kinase 9. (417 aa)
PMAIP1Uncharacterized protein. (54 aa)
BIRC3Baculoviral IAP repeat containing 3. (597 aa)
BOKBCL2 family apoptosis regulator BOK. (213 aa)
BIRC6Baculoviral IAP repeat containing 6. (4534 aa)
ENSPCOP00000004684Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSPCOP00000007435DUF4203 domain-containing protein. (348 aa)
TMEM198Transmembrane protein 198. (360 aa)
BIRC7Baculoviral IAP repeat containing 7. (283 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
C7orf31Chromosome 7 open reading frame 31. (589 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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