STRINGSTRING
PIK3CB PIK3CB SPHK2 SPHK2 MAP2K2 MAP2K2 RAC3 RAC3 PRKCG PRKCG ENSPCOP00000002686 ENSPCOP00000002686 ENSPCOP00000002927 ENSPCOP00000002927 SH2D7 SH2D7 KDR KDR RAF1 RAF1 NRAS NRAS PPP3CA PPP3CA MAPKAPK2 MAPKAPK2 SH2D2A SH2D2A PIK3R3 PIK3R3 MAPK3 MAPK3 PLA2G4A PLA2G4A PTGS2 PTGS2 LOC105819868 LOC105819868 ENSPCOP00000009588 ENSPCOP00000009588 RAC2 RAC2 KRAS KRAS NOS3 NOS3 SPHK1 SPHK1 REM1 REM1 PLCG2 PLCG2 CSDE1 CSDE1 PXN PXN PLA2G4B PLA2G4B PPP3CC PPP3CC SHC2 SHC2 MAPK12 MAPK12 MAPK11 MAPK11 ENSPCOP00000015102 ENSPCOP00000015102 NFATC2 NFATC2 PIK3CA PIK3CA MAP2K1 MAP2K1 LRRC45 LRRC45 RAC1 RAC1 MAPK14 MAPK14 PLA2G4D PLA2G4D PIK3R2 PIK3R2 PIK3R1 PIK3R1 SRC SRC PLA2G4E PLA2G4E AKT2 AKT2 HRAS HRAS PPP3R1 PPP3R1 GEM GEM CDC42 CDC42 PLA2G4F PLA2G4F VEGFA VEGFA PLCG1 PLCG1 PPP3CB PPP3CB PTK2 PTK2 MAPKAPK3 MAPKAPK3 JMJD7 JMJD7 AKT3 AKT3 AKT1 AKT1 CASP9 CASP9 PRKCA PRKCA PRKCB PRKCB MAPK1 MAPK1 PIK3CD PIK3CD TGFB1I1 TGFB1I1 MAPK13 MAPK13 RRAD RRAD BAD BAD HSPB1 HSPB1 PPP1R14B PPP1R14B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
SPHK2Sphingosine kinase 2. (660 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
RAC3Rac family small GTPase 3. (205 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
ENSPCOP00000002686CSD_1 domain-containing protein. (293 aa)
ENSPCOP00000002927Uncharacterized protein. (160 aa)
SH2D7SH2 domain containing 7. (432 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (400 aa)
SH2D2ASH2 domain containing 2A. (378 aa)
PIK3R3Uncharacterized protein. (454 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
PLA2G4APhospholipase A2. (749 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
LOC105819868Protein kinase domain-containing protein. (302 aa)
ENSPCOP00000009588Uncharacterized protein. (316 aa)
RAC2Rac family small GTPase 2. (192 aa)
KRASUncharacterized protein. (75 aa)
NOS3Nitric oxide synthase 3. (994 aa)
SPHK1Sphingosine kinase 1. (469 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1233 aa)
CSDE1Cold shock domain containing E1. (798 aa)
PXNPaxillin. (1073 aa)
PLA2G4BPhospholipase A2. (781 aa)
PPP3CCSerine/threonine-protein phosphatase. (520 aa)
SHC2Uncharacterized protein. (578 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
MAPK11Mitogen-activated protein kinase. (443 aa)
ENSPCOP00000015102Uncharacterized protein. (124 aa)
NFATC2Nuclear factor of activated T cells 2. (925 aa)
PIK3CAPhosphatidylinositol 3-kinase catalytic subunit type 3. (933 aa)
MAP2K1Mitogen-activated protein kinase kinase 1. (377 aa)
LRRC45Leucine rich repeat containing 45. (655 aa)
RAC1Rac family small GTPase 1. (211 aa)
MAPK14Mitogen-activated protein kinase 14. (340 aa)
PLA2G4DPhospholipase A2. (818 aa)
PIK3R2Uncharacterized protein. (726 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
SRCTyrosine-protein kinase. (543 aa)
PLA2G4EPhospholipase A2. (819 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PPP3R1Uncharacterized protein. (189 aa)
GEMGTP binding protein overexpressed in skeletal muscle. (160 aa)
CDC42Uncharacterized protein. (191 aa)
PLA2G4FPhospholipase A2. (847 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1304 aa)
PPP3CBSerine/threonine-protein phosphatase. (531 aa)
PTK2Protein tyrosine kinase 2. (1089 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (384 aa)
JMJD7Jumonji domain containing 7. (316 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (406 aa)
PRKCAUncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (575 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (461 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
BADBCL2 associated agonist of cell death. (168 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (206 aa)
PPP1R14BUncharacterized protein. (147 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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