STRINGSTRING
SERPINE1 SERPINE1 HGFAC HGFAC F7 F7 CD59 CD59 KNG1 KNG1 CLU CLU SERPINA5 SERPINA5 CR1 CR1 C9 C9 AADACL2 AADACL2 SERPINF2 SERPINF2 PROCR PROCR CD46 CD46 MBL2 MBL2 ITGB2 ITGB2 PLAT PLAT FGB FGB BDKRB2 BDKRB2 SSPO SSPO PROC PROC ENSPCOP00000008942 ENSPCOP00000008942 F12 F12 GZMK GZMK VSIG4 VSIG4 VTN VTN C3 C3 C1QC C1QC C8B C8B C2 C2 F2 F2 FGG FGG F2RL2 F2RL2 C1S C1S C7 C7 MROH2B MROH2B SERPINB2 SERPINB2 F2RL3 F2RL3 F13A1 F13A1 CFD CFD SERPINA1 SERPINA1 BDKRB1 BDKRB1 A2M A2M F9 F9 SERPING1 SERPING1 C1R C1R KLKB1 KLKB1 MASP1 MASP1 RC3H1 RC3H1 F13B F13B C8G C8G LOC105815321 LOC105815321 F8 F8 C4A C4A CR2 CR2 FGA FGA F3 F3 PLAUR PLAUR ENSPCOP00000025136 ENSPCOP00000025136 ENSPCOP00000025379 ENSPCOP00000025379 C1QA C1QA PROS1 PROS1 VWF VWF SERPIND1 SERPIND1 C1RL C1RL C4BPB C4BPB SERPINC1 SERPINC1 PLAU PLAU PLG PLG C6 C6 C4BPA C4BPA ENSPCOP00000028353 ENSPCOP00000028353 C5 C5 F11 F11 C8A C8A CFB CFB MASP2 MASP2 ZNF408 ZNF408 C1QB C1QB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
HGFACHGF activator. (653 aa)
F7Coagulation factor VII. (441 aa)
CD59UPAR/Ly6 domain-containing protein. (127 aa)
KNG1Uncharacterized protein. (391 aa)
CLUClusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (450 aa)
SERPINA5Serpin family A member 5; Belongs to the serpin family. (326 aa)
CR1Uncharacterized protein. (1529 aa)
C9Uncharacterized protein. (306 aa)
AADACL2Arylacetamide deacetylase like 2. (377 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (487 aa)
PROCRProtein C receptor. (238 aa)
CD46Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. (344 aa)
MBL2Mannose binding lectin 2. (247 aa)
ITGB2Integrin beta. (764 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (563 aa)
FGBFibrinogen beta chain. (492 aa)
BDKRB2Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (393 aa)
SSPOSCO-spondin. (5134 aa)
PROCProtein C, inactivator of coagulation factors Va and VIIIa. (487 aa)
ENSPCOP00000008942Uncharacterized protein. (149 aa)
F12Coagulation factor XII. (605 aa)
GZMKGranzyme K; Belongs to the peptidase S1 family. (268 aa)
VSIG4V-set and immunoglobulin domain containing 4. (399 aa)
VTNSMB domain-containing protein. (465 aa)
C3Complement C3. (1551 aa)
C1QCComplement C1q C chain. (245 aa)
C8BComplement C8 beta chain. (590 aa)
C2Complement C2; Belongs to the peptidase S1 family. (751 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
FGGFibrinogen gamma chain. (456 aa)
F2RL2Coagulation factor II thrombin receptor like 2. (373 aa)
C1SComplement C1s; Belongs to the peptidase S1 family. (687 aa)
C7Complement C7. (824 aa)
MROH2BMaestro heat like repeat family member 2B. (1457 aa)
SERPINB2Serpin family B member 2; Belongs to the serpin family. (417 aa)
F2RL3F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (376 aa)
F13A1Coagulation factor XIII A chain. (732 aa)
CFDComplement factor D; Belongs to the peptidase S1 family. (258 aa)
SERPINA1Serpin family A member 1; Belongs to the serpin family. (357 aa)
BDKRB1Bradykinin receptor B1. (274 aa)
A2MAlpha-2-macroglobulin. (1420 aa)
F9Coagulation factor IX. (461 aa)
SERPING1Serpin family G member 1; Belongs to the serpin family. (491 aa)
C1RComplement C1r; Belongs to the peptidase S1 family. (718 aa)
KLKB1Kallikrein B1; Belongs to the peptidase S1 family. (615 aa)
MASP1Mannan binding lectin serine peptidase 1. (699 aa)
RC3H1Ring finger and CCCH-type domains 1. (975 aa)
F13BCoagulation factor XIII B chain. (662 aa)
C8GComplement C8 gamma chain; Belongs to the calycin superfamily. Lipocalin family. (202 aa)
LOC105815321Uncharacterized protein. (1174 aa)
F8Coagulation factor VIII; Belongs to the multicopper oxidase family. (2348 aa)
C4AUncharacterized protein. (1742 aa)
CR2Complement C3d receptor 2. (1092 aa)
FGAFib_alpha domain-containing protein. (649 aa)
F3Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (294 aa)
PLAURPlasminogen activator, urokinase receptor. (333 aa)
ENSPCOP00000025136Uncharacterized protein. (298 aa)
ENSPCOP00000025379Uncharacterized protein. (532 aa)
C1QAComplement C1q A chain. (245 aa)
PROS1Protein S. (675 aa)
VWFVon Willebrand factor. (2807 aa)
SERPIND1Serpin family D member 1; Belongs to the serpin family. (499 aa)
C1RLComplement C1r subcomponent like; Belongs to the peptidase S1 family. (486 aa)
C4BPBComplement component 4 binding protein beta. (191 aa)
SERPINC1Serpin family C member 1; Belongs to the serpin family. (465 aa)
PLAUPlasminogen activator, urokinase. (432 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (772 aa)
C6Complement C6. (887 aa)
C4BPAComplement component 4 binding protein alpha. (596 aa)
ENSPCOP00000028353Uncharacterized protein. (130 aa)
C5Complement C5. (1527 aa)
F11Coagulation factor XI; Belongs to the peptidase S1 family. (625 aa)
C8AComplement C8 alpha chain. (586 aa)
CFBUncharacterized protein; Belongs to the peptidase S1 family. (764 aa)
MASP2Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family. (686 aa)
ZNF408Zinc finger protein 408. (719 aa)
C1QBComplement C1q B chain. (253 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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