STRINGSTRING
LOC105822640 LOC105822640 PRKCZ PRKCZ ADCY2 ADCY2 PRKG1 PRKG1 PTRHD1 PTRHD1 COL3A1 COL3A1 ARHGEF12 ARHGEF12 FERMT3 FERMT3 GUCY1A1 GUCY1A1 ENSPCOP00000007290 ENSPCOP00000007290 RHOA RHOA PRKACB PRKACB MYLK2 MYLK2 PRKCI PRKCI PLCB1 PLCB1 VASP VASP ACTB ACTB RAP1B RAP1B ITPR2 ITPR2 P2RY12 P2RY12 ITGB1 ITGB1 PTGS1 PTGS1 COL1A2 COL1A2 ADCY6 ADCY6 RAP1A RAP1A PIK3CD PIK3CD MAPK13 MAPK13 MYL12B MYL12B GNAS GNAS ZNF408 ZNF408 STIM1 STIM1 PLCB3 PLCB3 GNAI2 GNAI2 MAPK1 MAPK1 ADCY5 ADCY5 ENSPCOP00000029571 ENSPCOP00000029571 BTK BTK GP6 GP6 TBXAS1 TBXAS1 AKT1 AKT1 PRKACA PRKACA LOC105813679 LOC105813679 RDH13 RDH13 AKT3 AKT3 P2RY1 P2RY1 MYLK4 MYLK4 PPP1CA PPP1CA ITGA2B ITGA2B ITGA2 ITGA2 JMJD7 JMJD7 PLCB4 PLCB4 GP1BA GP1BA VAMP8 VAMP8 TLNRD1 TLNRD1 TLN1 TLN1 PIK3R6 PIK3R6 VWF VWF ENSPCOP00000025645 ENSPCOP00000025645 ITPR1 ITPR1 LYN LYN GNA13 GNA13 SRMS SRMS ADCY9 ADCY9 ADCY7 ADCY7 FGA FGA APBB1IP APBB1IP PIK3R5 PIK3R5 RDH14 RDH14 PLA2G4F PLA2G4F LOC105805812 LOC105805812 ORAI1 ORAI1 ACTG1 ACTG1 PPP1CC PPP1CC FCER1G FCER1G PTGIR PTGIR LCP2 LCP2 ENSPCOP00000021197 ENSPCOP00000021197 GP1BB GP1BB COL1A1 COL1A1 ENSPCOP00000020006 ENSPCOP00000020006 LOC105826342 LOC105826342 SNAP23 SNAP23 AKT2 AKT2 PLA2G4E PLA2G4E ENSPCOP00000018697 ENSPCOP00000018697 ITPR3 ITPR3 SRC SRC PIK3R1 PIK3R1 PIK3R2 PIK3R2 TLN2 TLN2 PLA2G4D PLA2G4D MAPK14 MAPK14 ADCY3 ADCY3 DHRSX DHRSX F2RL3 F2RL3 PIK3CB PIK3CB PIK3CG PIK3CG PIK3CA PIK3CA P2RX1 P2RX1 MAPK11 MAPK11 PPP1R12A PPP1R12A PLCB2 PLCB2 MAPK12 MAPK12 MYL12A MYL12A FGG FGG F2 F2 PLA2G4B PLA2G4B ADCY8 ADCY8 PLCG2 PLCG2 ROCK2 ROCK2 MYLK3 MYLK3 ADCY4 ADCY4 ADCY1 ADCY1 PPP1CB PPP1CB RASGRP2 RASGRP2 RHOC RHOC ARHGEF1 ARHGEF1 ENSPCOP00000010360 ENSPCOP00000010360 ENSPCOP00000010096 ENSPCOP00000010096 ACTL8 ACTL8 GUCY1A2 GUCY1A2 NOS3 NOS3 SYK SYK LOC105819868 LOC105819868 GUCY1B1 GUCY1B1 MYLK MYLK PLA2G4A PLA2G4A ARHGAP35 ARHGAP35 TBXA2R TBXA2R RASGRP1 RASGRP1 ENSPCOP00000008641 ENSPCOP00000008641 FYN FYN MAPK3 MAPK3 PIK3R3 PIK3R3 SSPO SSPO ROCK1 ROCK1 FGB FGB GNAI1 GNAI1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC105822640Integrin beta; Belongs to the integrin beta chain family. (454 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
ADCY2Adenylate cyclase 2. (904 aa)
PRKG1Protein kinase cGMP-dependent 1. (593 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
COL3A1Collagen type III alpha 1 chain. (1371 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1496 aa)
FERMT3Fermitin family member 3. (662 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
ENSPCOP00000007290Uncharacterized protein. (174 aa)
RHOARas homolog family member A. (193 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (399 aa)
MYLK2Myosin light chain kinase 2. (596 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (522 aa)
PLCB1Phosphoinositide phospholipase C. (1010 aa)
VASPVasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (379 aa)
ACTBActin beta. (378 aa)
RAP1BUncharacterized protein. (184 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2702 aa)
P2RY12Purinergic receptor P2Y12. (342 aa)
ITGB1Integrin beta. (585 aa)
PTGS1Prostaglandin-endoperoxide synthase 1. (633 aa)
COL1A2Collagen type I alpha 2 chain. (1364 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1167 aa)
RAP1ARAP1A, member of RAS oncogene family. (165 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
MYL12BMyosin light chain 12B. (172 aa)
GNASUncharacterized protein. (394 aa)
ZNF408Zinc finger protein 408. (719 aa)
STIM1Stromal interaction molecule 1. (784 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
GNAI2G protein subunit alpha i2. (355 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1258 aa)
ENSPCOP00000029571HNOB domain-containing protein. (173 aa)
BTKTyrosine-protein kinase. (647 aa)
GP6IG domain-containing protein. (287 aa)
TBXAS1Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (573 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
LOC105813679Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (744 aa)
RDH13Retinol dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (334 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
MYLK4Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (389 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1039 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1129 aa)
JMJD7Jumonji domain containing 7. (316 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1197 aa)
GP1BAGlycoprotein Ib platelet subunit alpha. (598 aa)
VAMP8Vesicle associated membrane protein 8. (100 aa)
TLNRD1Talin rod domain containing 1. (364 aa)
TLN1Talin 1. (2548 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (756 aa)
VWFVon Willebrand factor. (2807 aa)
ENSPCOP00000025645Uncharacterized protein. (162 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2732 aa)
LYNTyrosine-protein kinase. (512 aa)
GNA13G protein subunit alpha 13. (377 aa)
SRMSTyrosine-protein kinase. (496 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
FGAFib_alpha domain-containing protein. (649 aa)
APBB1IPAmyloid beta precursor protein binding family B member 1 interacting protein. (649 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (879 aa)
RDH14Retinol dehydrogenase 14; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (335 aa)
PLA2G4FPhospholipase A2. (847 aa)
LOC105805812Uncharacterized protein. (172 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (307 aa)
ACTG1Actin gamma 1. (404 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
FCER1GFc fragment of IgE receptor Ig. (86 aa)
PTGIRProstaglandin I2 receptor; Belongs to the G-protein coupled receptor 1 family. (386 aa)
LCP2Lymphocyte cytosolic protein 2. (493 aa)
ENSPCOP00000021197Synaptosomal-associated protein; Belongs to the SNAP-25 family. (192 aa)
GP1BBGlycoprotein Ib platelet subunit beta. (204 aa)
COL1A1Collagen type I alpha 1 chain. (1461 aa)
ENSPCOP00000020006t-SNARE coiled-coil homology domain-containing protein. (172 aa)
LOC105826342Uncharacterized protein. (170 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PLA2G4EPhospholipase A2. (819 aa)
ENSPCOP00000018697Uncharacterized protein. (441 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2664 aa)
SRCTyrosine-protein kinase. (543 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PIK3R2Uncharacterized protein. (726 aa)
TLN2Talin 2. (2542 aa)
PLA2G4DPhospholipase A2. (818 aa)
MAPK14Mitogen-activated protein kinase 14. (340 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
DHRSXDehydrogenase/reductase X-linked. (292 aa)
F2RL3F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (376 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
PIK3CAPhosphatidylinositol 3-kinase catalytic subunit type 3. (933 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
MAPK11Mitogen-activated protein kinase. (443 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1000 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
MYL12AUncharacterized protein. (172 aa)
FGGFibrinogen gamma chain. (456 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
PLA2G4BPhospholipase A2. (781 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1229 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1233 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1361 aa)
MYLK3Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (496 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (282 aa)
RASGRP2RAS guanyl releasing protein 2. (611 aa)
RHOCRas homolog family member C. (193 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (967 aa)
ENSPCOP00000010360AGC-kinase C-terminal domain-containing protein. (86 aa)
ENSPCOP00000010096Uncharacterized protein. (141 aa)
ACTL8Actin like 8; Belongs to the actin family. (351 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (729 aa)
NOS3Nitric oxide synthase 3. (994 aa)
SYKSpleen associated tyrosine kinase. (637 aa)
LOC105819868Protein kinase domain-containing protein. (302 aa)
GUCY1B1Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (176 aa)
MYLKMyosin light chain kinase. (1848 aa)
PLA2G4APhospholipase A2. (749 aa)
ARHGAP35Rho GTPase activating protein 35. (1510 aa)
TBXA2RThromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family. (343 aa)
RASGRP1RAS guanyl releasing protein 1. (827 aa)
ENSPCOP00000008641Uncharacterized protein. (715 aa)
FYNTyrosine-protein kinase. (537 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
PIK3R3Uncharacterized protein. (454 aa)
SSPOSCO-spondin. (5134 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1316 aa)
FGBFibrinogen beta chain. (492 aa)
GNAI1G protein subunit alpha i1. (354 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
Server load: low (26%) [HD]