STRINGSTRING
MAPK9 MAPK9 FOSB FOSB CCL11 CCL11 LCN2 LCN2 MAP3K7 MAP3K7 IL17D IL17D JUND JUND MAPK6 MAPK6 IL5 IL5 HSP90AB1 HSP90AB1 TRAF3 TRAF3 CCL20 CCL20 NFKB1 NFKB1 IL6 IL6 MAPK3 MAPK3 CCL2 CCL2 PTGS2 PTGS2 LOC105819868 LOC105819868 IL13 IL13 ENSPCOP00000009948 ENSPCOP00000009948 CSF2 CSF2 TRAF3IP2 TRAF3IP2 IL1B IL1B MMP10 MMP10 MMP9 MMP9 TAB3 TAB3 IL17B IL17B MAPK12 MAPK12 NFKBIA NFKBIA CCL17 CCL17 IL17F IL17F MAPK11 MAPK11 TRAF2 TRAF2 S100A9 S100A9 TNF TNF MAPK7 MAPK7 CXCL6 CXCL6 LOC105816498 LOC105816498 IL17RE IL17RE TRADD TRADD TBK1 TBK1 MAPK14 MAPK14 IL4 IL4 CASP3 CASP3 LOC105812452 LOC105812452 ENSPCOP00000018566 ENSPCOP00000018566 USP25 USP25 IL17RC IL17RC IL17A IL17A IFNG IFNG IKBKB IKBKB MMP1 MMP1 FADD FADD MAPK10 MAPK10 TAB2 TAB2 ENSPCOP00000022199 ENSPCOP00000022199 MMP3 MMP3 GSK3B GSK3B SRSF1 SRSF1 MAPK4 MAPK4 CASP8 CASP8 CXCL10 CXCL10 CXCL8 CXCL8 HSP90B1 HSP90B1 IL25 IL25 ENSPCOP00000026663 ENSPCOP00000026663 IKBKG IKBKG IKBKE IKBKE MAPK8 MAPK8 CEBPB CEBPB ENSPCOP00000028553 ENSPCOP00000028553 IL17C IL17C ANAPC5 ANAPC5 FOSL1 FOSL1 CHUK CHUK MAPK1 MAPK1 MAPK13 MAPK13 TNFAIP3 TNFAIP3 HSP90AA1 HSP90AA1 TRAF5 TRAF5 CSF3 CSF3 MMP13 MMP13 RELA RELA FOS FOS S100A8 S100A8 IL17RA IL17RA TRAF6 TRAF6 IL17RB IL17RB ELAVL1 ELAVL1 TRAF4 TRAF4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK9Mitogen-activated protein kinase 9. (417 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
CCL11C-C motif chemokine. (97 aa)
LCN2Lipocalin 2; Belongs to the calycin superfamily. Lipocalin family. (197 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (553 aa)
IL17DInterleukin 17D. (200 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (348 aa)
MAPK6Mitogen-activated protein kinase 6. (722 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (133 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (715 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (564 aa)
CCL20C-C motif chemokine. (96 aa)
NFKB1Nuclear factor kappa B subunit 1. (961 aa)
IL6Uncharacterized protein. (211 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
CCL2C-C motif chemokine. (99 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
LOC105819868Protein kinase domain-containing protein. (302 aa)
IL13Interleukin 13. (132 aa)
ENSPCOP00000009948Uncharacterized protein. (605 aa)
CSF2Colony stimulating factor 2. (146 aa)
TRAF3IP2TRAF3 interacting protein 2. (562 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
MMP10Matrix metallopeptidase 10; Belongs to the peptidase M10A family. (287 aa)
MMP9Matrix metallopeptidase 9. (709 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (710 aa)
IL17BInterleukin 17B. (180 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
CCL17C-C motif chemokine. (102 aa)
IL17FInterleukin 17F. (164 aa)
MAPK11Mitogen-activated protein kinase. (443 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
S100A9S100 calcium binding protein A9; Belongs to the S-100 family. (154 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (235 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (802 aa)
CXCL6C-X-C motif chemokine. (116 aa)
LOC105816498Uncharacterized protein. (3898 aa)
IL17REInterleukin 17 receptor E. (705 aa)
TRADDTNFRSF1A associated via death domain. (309 aa)
TBK1TANK binding kinase 1. (690 aa)
MAPK14Mitogen-activated protein kinase 14. (340 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
LOC105812452HATPase_c domain-containing protein. (680 aa)
ENSPCOP00000018566Uncharacterized protein. (113 aa)
USP25Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (884 aa)
IL17RCInterleukin 17 receptor C. (775 aa)
IL17AInterleukin 17A. (153 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (747 aa)
MMP1Matrix metallopeptidase 1. (414 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (205 aa)
MAPK10Mitogen-activated protein kinase. (473 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
ENSPCOP00000022199Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (282 aa)
MMP3Matrix metallopeptidase 3. (477 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (390 aa)
SRSF1Uncharacterized protein. (253 aa)
MAPK4Mitogen-activated protein kinase 4. (587 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (395 aa)
CXCL10C-X-C motif chemokine. (98 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
HSP90B1HATPase_c domain-containing protein. (793 aa)
IL25Interleukin 25. (161 aa)
ENSPCOP00000026663Uncharacterized protein. (223 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (490 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa)
MAPK8Mitogen-activated protein kinase 8. (346 aa)
CEBPBCCAAT/enhancer-binding protein. (347 aa)
ENSPCOP00000028553HATPase_c domain-containing protein. (333 aa)
IL17CInterleukin 17C. (197 aa)
ANAPC5Anaphase promoting complex subunit 5. (755 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (272 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (682 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
TNFAIP3TNF alpha induced protein 3. (792 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (816 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (536 aa)
CSF3Colony stimulating factor 3. (199 aa)
MMP13Matrix metallopeptidase 13. (386 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (381 aa)
S100A8S100 calcium binding protein A8; Belongs to the S-100 family. (89 aa)
IL17RAInterleukin 17 receptor A. (847 aa)
TRAF6TNF receptor-associated factor. (498 aa)
IL17RBInterleukin 17 receptor B. (496 aa)
ELAVL1ELAV-like protein; Belongs to the RRM elav family. (326 aa)
TRAF4TNF receptor-associated factor. (470 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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