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GNGT2 GNGT2 PPP2R2B PPP2R2B GNB3 GNB3 ENSPCOP00000031946 ENSPCOP00000031946 GNAS GNAS GNG7 GNG7 ARR3 ARR3 GRIA4 GRIA4 GNAO1 GNAO1 MAPK13 MAPK13 PLCB3 PLCB3 GNAI2 GNAI2 ADCY5 ADCY5 GNG10 GNG10 GNB2 GNB2 PPP3CA PPP3CA PLCB1 PLCB1 KIF5B KIF5B SLC6A3 SLC6A3 GNG8 GNG8 PRKACB PRKACB PPP2CB PPP2CB PPP2R3B PPP2R3B PRKCB PRKCB PRKCA PRKCA AKT1 AKT1 PRKACA PRKACA PPP2R5B PPP2R5B AKT3 AKT3 MAPK8 MAPK8 PPP1R1B PPP1R1B PPP1CA PPP1CA DRD4 DRD4 KCNJ6 KCNJ6 DRD1 DRD1 GRIN2B GRIN2B PLCB4 PLCB4 ENSPCOP00000026249 ENSPCOP00000026249 ATF2 ATF2 MAOB MAOB CREB3L1 CREB3L1 CREB3 CREB3 PPP2CA PPP2CA KIF5A KIF5A PPP3CB PPP3CB ITPR1 ITPR1 CAMK2A CAMK2A ARRB2 ARRB2 KIF5C KIF5C TH TH SLC18A2 SLC18A2 ENSPCOP00000024532 ENSPCOP00000024532 GNG2 GNG2 ENSPCOP00000023702 ENSPCOP00000023702 GNG13 GNG13 PPP2R5A PPP2R5A GSK3B GSK3B KCNJ3 KCNJ3 PPP2R2A PPP2R2A CREB5 CREB5 CAMK2G CAMK2G GNAL GNAL ARNTL ARNTL MAPK10 MAPK10 GNB4 GNB4 PPP1CC PPP1CC MAOA MAOA CAMK2D CAMK2D SCN1A SCN1A GNG11 GNG11 PPP2R1B PPP2R1B GNB1 GNB1 AKT2 AKT2 SLC18A1 SLC18A1 LOC105811493 LOC105811493 CREB1 CREB1 PPP2R3A PPP2R3A ITPR3 ITPR3 COMT COMT PPP2R5D PPP2R5D ARRB1 ARRB1 ATF4 ATF4 ATF6B ATF6B CALML4 CALML4 MAPK14 MAPK14 CACNA1C CACNA1C CREB3L4 CREB3L4 LOC105823863 LOC105823863 CALY CALY PVALEF PVALEF PPP2R3C PPP2R3C PPP2R2D PPP2R2D GNB5 GNB5 GRIA1 GRIA1 MAPK11 MAPK11 CLOCK CLOCK PLCB2 PLCB2 MAPK12 MAPK12 CALM2 CALM2 ENSPCOP00000013862 ENSPCOP00000013862 GSK3A GSK3A CACNA1D CACNA1D PPP3CC PPP3CC GNG3 GNG3 CREB3L3 CREB3L3 KCNJ5 KCNJ5 CACNA1A CACNA1A ENSPCOP00000007290 ENSPCOP00000007290 KCNJ9 KCNJ9 CALM3 CALM3 PPP1CB PPP1CB GRIA2 GRIA2 ENSPCOP00000010764 ENSPCOP00000010764 DDC DDC GRIA3 GRIA3 CALM1 CALM1 ENSPCOP00000009588 ENSPCOP00000009588 LOC105819868 LOC105819868 DRD3 DRD3 ENSPCOP00000008641 ENSPCOP00000008641 CREB3L2 CREB3L2 PPP2R2C PPP2R2C ENSPCOP00000007681 ENSPCOP00000007681 GNAI1 GNAI1 CAMK2B CAMK2B FOS FOS CACNA1B CACNA1B PPP2R5C PPP2R5C ENSPCOP00000000307 ENSPCOP00000000307 GNG12 GNG12 PPP2R5E PPP2R5E GNG4 GNG4 PRKCG PRKCG MAPK9 MAPK9 GRIN2A GRIN2A ENSPCOP00000002207 ENSPCOP00000002207 ARSI ARSI DRD2 DRD2 ENSPCOP00000002561 ENSPCOP00000002561 PPP2R1A PPP2R1A ITPR2 ITPR2 DRD5 DRD5
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (509 aa)
GNB3G protein subunit beta 3. (340 aa)
ENSPCOP00000031946G protein gamma domain-containing protein. (68 aa)
GNASUncharacterized protein. (394 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ARR3Arrestin 3. (390 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (831 aa)
GNAO1G protein subunit alpha o1. (354 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
GNAI2G protein subunit alpha i2. (355 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1258 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNB2G protein subunit beta 2. (340 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
PLCB1Phosphoinositide phospholipase C. (1010 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (829 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (619 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (399 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
PPP2R3BProtein phosphatase 2 regulatory subunit B''beta. (479 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
PRKCAUncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (575 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (501 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
MAPK8Mitogen-activated protein kinase 8. (346 aa)
PPP1R1BProtein phosphatase 1 regulatory inhibitor subunit 1B. (204 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (333 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (423 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1485 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1197 aa)
ENSPCOP00000026249Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (79 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
MAOBAmine oxidase. (528 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (520 aa)
CREB3cAMP responsive element binding protein 3. (373 aa)
PPP2CASerine/threonine-protein phosphatase. (295 aa)
KIF5AKinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1024 aa)
PPP3CBSerine/threonine-protein phosphatase. (531 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2732 aa)
CAMK2AProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (471 aa)
ARRB2Arrestin beta 2. (441 aa)
KIF5CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (957 aa)
THTyrosine hydroxylase. (497 aa)
SLC18A2Solute carrier family 18 member A2. (491 aa)
ENSPCOP00000024532Uncharacterized protein; Belongs to the calmodulin family. (142 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (109 aa)
ENSPCOP00000023702Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (61 aa)
GNG13G protein subunit gamma 13. (67 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (447 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (390 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (384 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (600 aa)
GNALG protein subunit alpha L. (454 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator like. (626 aa)
MAPK10Mitogen-activated protein kinase. (473 aa)
GNB4G protein subunit beta 4. (321 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
MAOAAmine oxidase. (528 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (503 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1741 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (552 aa)
GNB1G protein subunit beta 1. (334 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
SLC18A1Solute carrier family 18 member A1. (525 aa)
LOC105811493Transmembrane O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones (By similarity). Required for auditory function (By similarity). Component of the cochlear hair cell's mechanotransduction (MET) machinery. Involved in the assembly of the asymmetric tip-link MET complex. Required for transportation of TMC1 and TMC2 proteins into the mechanically sensitive stereocilia of the hair cells. The function in MET is independent of the enzymatic activity (By similarity). (288 aa)
CREB1cAMP responsive element binding protein 1. (280 aa)
PPP2R3AProtein phosphatase 2 regulatory subunit B''alpha. (1150 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2664 aa)
COMTCatechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (221 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (598 aa)
ARRB1Arrestin beta 1. (429 aa)
ATF4Activating transcription factor 4. (351 aa)
ATF6BActivating transcription factor 6 beta. (702 aa)
CALML4Calmodulin like 4. (178 aa)
MAPK14Mitogen-activated protein kinase 14. (340 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2016 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (395 aa)
LOC105823863Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CALYCalcyon neuron specific vesicular protein. (213 aa)
PVALEFParvalbumin like EF-hand containing. (126 aa)
PPP2R3CProtein phosphatase 2 regulatory subunit B''gamma. (410 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (453 aa)
GNB5G protein subunit beta 5. (395 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (906 aa)
MAPK11Mitogen-activated protein kinase. (443 aa)
CLOCKClock circadian regulator. (745 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (138 aa)
ENSPCOP00000013862SER_THR_PHOSPHATASE domain-containing protein. (209 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2180 aa)
PPP3CCSerine/threonine-protein phosphatase. (520 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (456 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2494 aa)
ENSPCOP00000007290Uncharacterized protein. (174 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (393 aa)
CALM3Calmodulin 1; Belongs to the calmodulin family. (149 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (282 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (857 aa)
ENSPCOP00000010764EF-hand domain-containing protein; Belongs to the calmodulin family. (109 aa)
DDCDopa decarboxylase. (480 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (894 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (150 aa)
ENSPCOP00000009588Uncharacterized protein. (316 aa)
LOC105819868Protein kinase domain-containing protein. (302 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (400 aa)
ENSPCOP00000008641Uncharacterized protein. (715 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (508 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa)
ENSPCOP00000007681EF-hand domain-containing protein. (132 aa)
GNAI1G protein subunit alpha i1. (354 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (665 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (381 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (1761 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (542 aa)
ENSPCOP00000000307Uncharacterized protein; Belongs to the calmodulin family. (142 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
MAPK9Mitogen-activated protein kinase 9. (417 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1462 aa)
ENSPCOP00000002207Uncharacterized protein; Belongs to the calmodulin family. (113 aa)
ARSIArylsulfatase family member I. (572 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
ENSPCOP00000002561Uncharacterized protein. (546 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2702 aa)
DRD5Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (434 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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