STRINGSTRING
RAF1 RAF1 NRAS NRAS PLCB1 PLCB1 PPP2CB PPP2CB ENSPCOP00000007290 ENSPCOP00000007290 GUCY1A1 GUCY1A1 GNAI1 GNAI1 MAPK3 MAPK3 ENSPCOP00000008641 ENSPCOP00000008641 PLA2G4A PLA2G4A GUCY1B1 GUCY1B1 PPP1R17 PPP1R17 ENSPCOP00000009588 ENSPCOP00000009588 KRAS KRAS GRIA3 GRIA3 GUCY1A2 GUCY1A2 ENSPCOP00000010360 ENSPCOP00000010360 FBXO21 FBXO21 GRIA2 GRIA2 ARAF ARAF GNAZ GNAZ CACNA1A CACNA1A CSDE1 CSDE1 PLA2G4B PLA2G4B RYR1 RYR1 ENSPCOP00000013862 ENSPCOP00000013862 PLCB2 PLCB2 GRIA1 GRIA1 CRHR1 CRHR1 MAP2K1 MAP2K1 PLA2G4D PLA2G4D GRM1 GRM1 ITPR3 ITPR3 PLA2G4E PLA2G4E GNA12 GNA12 IGF1 IGF1 NOS1 NOS1 PRKG1 PRKG1 HRAS HRAS PPP2R1B PPP2R1B IGF1R IGF1R PLA2G4F PLA2G4F BRAF BRAF GNA13 GNA13 LYN LYN ITPR1 ITPR1 PPP2CA PPP2CA GRID2 GRID2 PLCB4 PLCB4 JMJD7 JMJD7 LOC105813679 LOC105813679 PRKCA PRKCA PRKCB PRKCB ENSPCOP00000029571 ENSPCOP00000029571 MAPK1 MAPK1 GNAI2 GNAI2 PLCB3 PLCB3 GNAO1 GNAO1 GNAS GNAS MAP2K2 MAP2K2 PRKCG PRKCG ENSPCOP00000002561 ENSPCOP00000002561 ENSPCOP00000002686 ENSPCOP00000002686 PPP2R1A PPP2R1A ITPR2 ITPR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
PLCB1Phosphoinositide phospholipase C. (1010 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
ENSPCOP00000007290Uncharacterized protein. (174 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
GNAI1G protein subunit alpha i1. (354 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
ENSPCOP00000008641Uncharacterized protein. (715 aa)
PLA2G4APhospholipase A2. (749 aa)
GUCY1B1Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (176 aa)
PPP1R17Protein phosphatase 1 regulatory subunit 17. (155 aa)
ENSPCOP00000009588Uncharacterized protein. (316 aa)
KRASUncharacterized protein. (75 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (894 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (729 aa)
ENSPCOP00000010360AGC-kinase C-terminal domain-containing protein. (86 aa)
FBXO21F-box protein 21. (628 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (857 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (609 aa)
GNAZG protein subunit alpha z. (355 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2494 aa)
CSDE1Cold shock domain containing E1. (798 aa)
PLA2G4BPhospholipase A2. (781 aa)
RYR1Ryanodine receptor 1. (4928 aa)
ENSPCOP00000013862SER_THR_PHOSPHATASE domain-containing protein. (209 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (906 aa)
CRHR1Corticotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 2 family. (415 aa)
MAP2K1Mitogen-activated protein kinase kinase 1. (377 aa)
PLA2G4DPhospholipase A2. (818 aa)
GRM1Glutamate metabotropic receptor 1. (1188 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2664 aa)
PLA2G4EPhospholipase A2. (819 aa)
GNA12G protein subunit alpha 12. (380 aa)
IGF1Insulin like growth factor 1. (208 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1434 aa)
PRKG1Protein kinase cGMP-dependent 1. (593 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (552 aa)
IGF1RTyrosine-protein kinase receptor. (1350 aa)
PLA2G4FPhospholipase A2. (847 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (745 aa)
GNA13G protein subunit alpha 13. (377 aa)
LYNTyrosine-protein kinase. (512 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2732 aa)
PPP2CASerine/threonine-protein phosphatase. (295 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (962 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1197 aa)
JMJD7Jumonji domain containing 7. (316 aa)
LOC105813679Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (744 aa)
PRKCAUncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (575 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
ENSPCOP00000029571HNOB domain-containing protein. (173 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
GNAI2G protein subunit alpha i2. (355 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
GNAO1G protein subunit alpha o1. (354 aa)
GNASUncharacterized protein. (394 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
ENSPCOP00000002561Uncharacterized protein. (546 aa)
ENSPCOP00000002686CSD_1 domain-containing protein. (293 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2702 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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