109 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GNAS	Uncharacterized protein. (394 aa)
	WNT5B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (332 aa)
	TCF7	Transcription factor 7. (303 aa)
	RRAD	GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
	GNAO1	G protein subunit alpha o1. (354 aa)
	WNT2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
	PLCB3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
	CALM3	Calmodulin 1; Belongs to the calmodulin family. (149 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
	ADCY4	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
	REM1	GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1229 aa)
	TCF7L2	Transcription factor 7 like 2. (619 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
	ENSPCOP00000024532	Uncharacterized protein; Belongs to the calmodulin family. (142 aa)
	CAMK2A	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (471 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	CREB3	cAMP responsive element binding protein 3. (373 aa)
	CREB3L1	cAMP responsive element binding protein 3 like 1. (520 aa)
	WNT8A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1197 aa)
	DVL1	Dishevelled segment polarity protein 1. (722 aa)
	MITF	Melanocyte inducing transcription factor. (526 aa)
	WNT8B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
	PRKCA	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (575 aa)
	PRKCB	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
	WNT10A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
	TCF7L1	Transcription factor 7 like 1. (590 aa)
	ADCY5	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1258 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
	GNAI2	G protein subunit alpha i2. (355 aa)
	TYRP1	Uncharacterized protein. (270 aa)
	WNT2B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
	ENSPCOP00000000307	Uncharacterized protein; Belongs to the calmodulin family. (142 aa)
	DCT	Dopachrome tautomerase. (419 aa)
	WNT7B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	PTRHD1	Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
	MAP2K2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
	ADCY2	Adenylate cyclase 2. (904 aa)
	WNT10B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
	PRKCG	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
	ENSPCOP00000002207	Uncharacterized protein; Belongs to the calmodulin family. (113 aa)
	ARSI	Arylsulfatase family member I. (572 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1167 aa)
	WNT7A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (190 aa)
	ENSPCOP00000002686	CSD_1 domain-containing protein. (293 aa)
	ASIP	Agouti signaling protein. (129 aa)
	FZD9	Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
	FZD5	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
	LEF1	Lymphoid enhancer binding factor 1. (432 aa)
	RAF1	Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
	FZD7	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
	NRAS	NRAS proto-oncogene, GTPase. (189 aa)
	PLCB1	Phosphoinositide phospholipase C. (1010 aa)
	WNT11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (399 aa)
	DVL2	Dishevelled segment polarity protein 2. (736 aa)
	EDN1	Endothelin 1. (193 aa)
	ENSPCOP00000007290	Uncharacterized protein. (174 aa)
	CAMK2B	Calcium/calmodulin dependent protein kinase II beta. (665 aa)
	GNAI1	G protein subunit alpha i1. (354 aa)
	ENSPCOP00000007681	EF-hand domain-containing protein. (132 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	WNT1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
	CREB3L2	cAMP responsive element binding protein 3 like 2. (508 aa)
	WNT16	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
	WNT9A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
	ENSPCOP00000008641	Uncharacterized protein. (715 aa)
	FZD8	Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (406 aa)
	EFCAB3	Uncharacterized protein. (185 aa)
	ENSPCOP00000009588	Uncharacterized protein. (316 aa)
	KRAS	Uncharacterized protein. (75 aa)
	TYR	Tyrosinase. (530 aa)
	CALM1	Calmodulin 1; Belongs to the calmodulin family. (150 aa)
	FZD3	Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
	ENSPCOP00000010764	EF-hand domain-containing protein; Belongs to the calmodulin family. (109 aa)
	WNT6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
	CREB3L3	cAMP responsive element binding protein 3 like 3. (456 aa)
	CSDE1	Cold shock domain containing E1. (798 aa)
	CALM2	Calmodulin 2; Belongs to the calmodulin family. (138 aa)
	EDNRB	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (485 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
	FZD4	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
	PVALEF	Parvalbumin like EF-hand containing. (126 aa)
	FZD6	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
	CREB3L4	cAMP responsive element binding protein 3 like 4. (395 aa)
	MAP2K1	Mitogen-activated protein kinase kinase 1. (377 aa)
	DVL3	Dishevelled segment polarity protein 3. (716 aa)
	ADCY3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
	CALML4	Calmodulin like 4. (178 aa)
	CREB1	cAMP responsive element binding protein 1. (280 aa)
	FZD2	Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (547 aa)
	EP300	E1A binding protein p300. (2424 aa)
	HRAS	HRas proto-oncogene, GTPase. (189 aa)
	CREBBP	CREB binding protein. (2449 aa)
	WNT4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	GEM	GTP binding protein overexpressed in skeletal muscle. (160 aa)
	CAMK2D	Calcium/calmodulin dependent protein kinase II delta. (503 aa)
	KITLG	Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
	CAMK2G	Calcium/calmodulin dependent protein kinase II gamma. (600 aa)
	WNT9B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	GSK3B	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (390 aa)
	KIT	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
	WNT3	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
	POMC	Proopiomelanocortin. (258 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	ENSPCOP00000011503	ENSPCOP00000001482	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 2.	0.651
ADCY1	ADCY4	ENSPCOP00000011503	ENSPCOP00000011755	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.636
ADCY1	ADCY5	ENSPCOP00000011503	ENSPCOP00000029755	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.634
ADCY1	ADCY6	ENSPCOP00000011503	ENSPCOP00000002439	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.635
ADCY1	ADCY7	ENSPCOP00000011503	ENSPCOP00000024141	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.665
ADCY1	ADCY9	ENSPCOP00000011503	ENSPCOP00000024273	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.819
ADCY1	CALM1	ENSPCOP00000011503	ENSPCOP00000009692	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 1; Belongs to the calmodulin family.	0.683
ADCY1	CALM2	ENSPCOP00000011503	ENSPCOP00000013912	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 2; Belongs to the calmodulin family.	0.624
ADCY1	CALM3	ENSPCOP00000011503	ENSPCOP00000011445	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 1; Belongs to the calmodulin family.	0.683
ADCY1	CALML4	ENSPCOP00000011503	ENSPCOP00000017539	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 4.	0.900
ADCY1	CAMK2A	ENSPCOP00000011503	ENSPCOP00000025158	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.867
ADCY1	CAMK2B	ENSPCOP00000011503	ENSPCOP00000007426	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase II beta.	0.871
ADCY1	CAMK2D	ENSPCOP00000011503	ENSPCOP00000021794	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase II delta.	0.866
ADCY1	CAMK2G	ENSPCOP00000011503	ENSPCOP00000022326	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase II gamma.	0.798
ADCY1	CSDE1	ENSPCOP00000011503	ENSPCOP00000012627	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Cold shock domain containing E1.	0.486
ADCY1	EFCAB3	ENSPCOP00000011503	ENSPCOP00000009463	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.561
ADCY1	ENSPCOP00000000307	ENSPCOP00000011503	ENSPCOP00000000307	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the calmodulin family.	0.683
ADCY1	ENSPCOP00000002207	ENSPCOP00000011503	ENSPCOP00000002207	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the calmodulin family.	0.624
ADCY1	ENSPCOP00000002686	ENSPCOP00000011503	ENSPCOP00000002686	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	CSD_1 domain-containing protein.	0.486
ADCY1	ENSPCOP00000007290	ENSPCOP00000011503	ENSPCOP00000007290	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.849