STRINGSTRING
CLEC10A CLEC10A PLCB1 PLCB1 PRKACB PRKACB GPX7 GPX7 ASGR1 ASGR1 ATP1A4 ATP1A4 CANX CANX CREB3L2 CREB3L2 ENSPCOP00000008641 ENSPCOP00000008641 LOC105811829 LOC105811829 ENSPCOP00000009588 ENSPCOP00000009588 SYCP1 SYCP1 ADCY1 ADCY1 ADCY4 ADCY4 ADCY8 ADCY8 ATP1B1 ATP1B1 ATP1A1 ATP1A1 ENSPCOP00000012404 ENSPCOP00000012404 CREB3L3 CREB3L3 GPX5 GPX5 PLCB2 PLCB2 DUOX2 DUOX2 CREB3L4 CREB3L4 PAX8 PAX8 TTF1 TTF1 TSHR TSHR ADCY3 ADCY3 ATF6B ATF6B ALB ALB ATF4 ATF4 TTR TTR ATP1A3 ATP1A3 ITPR3 ITPR3 CREB1 CREB1 TSHB TSHB ATP1B3 ATP1B3 DUOX1 DUOX1 GPX8 GPX8 CREB5 CREB5 SLC26A4 SLC26A4 GPX3 GPX3 GPX1 GPX1 SERPINA7 SERPINA7 ATP1B4 ATP1B4 ADCY7 ADCY7 ADCY9 ADCY9 ITPR1 ITPR1 CREB3 CREB3 HSP90B1 HSP90B1 CREB3L1 CREB3L1 ATF2 ATF2 DUOXA2 DUOXA2 TPO TPO PLCB4 PLCB4 HSPA5 HSPA5 GSR GSR IYD IYD PRKACA PRKACA GPX2 GPX2 ADCY6 ADCY6 PRKCA PRKCA PRKCB PRKCB ADCY5 ADCY5 PLCB3 PLCB3 ASGR2 ASGR2 GNAS GNAS ATP1A2 ATP1A2 ATP1B2 ATP1B2 LRP2 LRP2 GPX6 GPX6 SERPINA9 SERPINA9 FXYD2 FXYD2 ITPR2 ITPR2 TG TG PDIA4 PDIA4 TTF2 TTF2 PTRHD1 PTRHD1 SLC5A5 SLC5A5 ADCY2 ADCY2 PRKCG PRKCG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CLEC10AC-type lectin domain containing 10A. (316 aa)
PLCB1Phosphoinositide phospholipase C. (1010 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (399 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (186 aa)
ASGR1Asialoglycoprotein receptor 1. (291 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1031 aa)
CANXUncharacterized protein; Belongs to the calreticulin family. (290 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (508 aa)
ENSPCOP00000008641Uncharacterized protein. (715 aa)
LOC105811829Uncharacterized protein; Belongs to the heat shock protein 70 family. (649 aa)
ENSPCOP00000009588Uncharacterized protein. (316 aa)
SYCP1Synaptonemal complex protein 1. (767 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1229 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1023 aa)
ENSPCOP00000012404Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (125 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (456 aa)
GPX5Glutathione peroxidase; Belongs to the glutathione peroxidase family. (221 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
DUOX2Dual oxidase 2. (1540 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (395 aa)
PAX8Paired box 8. (458 aa)
TTF1Myb-like domain-containing protein. (370 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (739 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
ATF6BActivating transcription factor 6 beta. (702 aa)
ALBAlbumin. (494 aa)
ATF4Activating transcription factor 4. (351 aa)
TTRTransthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (147 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (1080 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2664 aa)
CREB1cAMP responsive element binding protein 1. (280 aa)
TSHBThyroid stimulating hormone subunit beta. (138 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
DUOX1Dual oxidase 1. (1553 aa)
GPX8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (176 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
SLC26A4Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (780 aa)
GPX3Glutathione peroxidase; Belongs to the glutathione peroxidase family. (222 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (193 aa)
SERPINA7Serpin family A member 7; Belongs to the serpin family. (418 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (352 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2732 aa)
CREB3cAMP responsive element binding protein 3. (373 aa)
HSP90B1HATPase_c domain-containing protein. (793 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (520 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
DUOXA2Dual oxidase maturation factor 2. (320 aa)
TPOThyroid peroxidase. (927 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1197 aa)
HSPA5Uncharacterized protein; Belongs to the heat shock protein 70 family. (654 aa)
GSRGlutathione-disulfide reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (381 aa)
IYDIodotyrosine deiodinase. (289 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
GPX2Glutathione peroxidase; Belongs to the glutathione peroxidase family. (150 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1167 aa)
PRKCAUncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (575 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1258 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
ASGR2Asialoglycoprotein receptor 2. (287 aa)
GNASUncharacterized protein. (394 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
LRP2LDL receptor related protein 2. (4654 aa)
GPX6Glutathione peroxidase; Belongs to the glutathione peroxidase family. (219 aa)
SERPINA9Serpin family A member 9; Belongs to the serpin family. (418 aa)
FXYD2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (66 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2702 aa)
TGThyroglobulin. (2704 aa)
PDIA4Protein disulfide-isomerase A4. (644 aa)
TTF2Transcription termination factor 2. (1165 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
SLC5A5Solute carrier family 5 member 5; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (640 aa)
ADCY2Adenylate cyclase 2. (904 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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