STRINGSTRING
G6PC2 G6PC2 AKT2 AKT2 PRKAG3 PRKAG3 AGRP AGRP TRADD TRADD G6PC3 G6PC3 POMC POMC PCK1 PCK1 ACACB ACACB STAT3 STAT3 CHUK CHUK PTPN11 PTPN11 G6PC G6PC AKT1 AKT1 ACSBG2 ACSBG2 AKT3 AKT3 TNF TNF ADIPOR1 ADIPOR1 TRAF2 TRAF2 ACSL1 ACSL1 NFKBIA NFKBIA TNFRSF1B TNFRSF1B SLC2A4 SLC2A4 ADIPOQ ADIPOQ NFKBIE NFKBIE CPT1C CPT1C PPARA PPARA CPT1B CPT1B LEPR LEPR NFKBIB NFKBIB CD36 CD36 NPY NPY ADIPOR2 ADIPOR2 NFKB1 NFKB1 RXRB RXRB PRKAB2 PRKAB2 RXRA RXRA PRKAG1 PRKAG1 LEP LEP ACSL5 ACSL5 STK11 STK11 SLC2A3 SLC2A3 PRKAB1 PRKAB1 CAMKK2 CAMKK2 SLC2A1 SLC2A1 MAPK9 MAPK9 MTOR MTOR ENSPCOP00000000328 ENSPCOP00000000328 CPT1A CPT1A PRKAG2 PRKAG2 MAPK8 MAPK8 PCK2 PCK2 TNFRSF1A TNFRSF1A PRKAA2 PRKAA2 RELA RELA IKBKG IKBKG SOCS3 SOCS3 PRKCQ PRKCQ ACSBG1 ACSBG1 ACSL4 ACSL4 PRKAA1 PRKAA1 ACSL6 ACSL6 MAPK10 MAPK10 PPARGC1A PPARGC1A IKBKB IKBKB ACSL3 ACSL3 IRS2 IRS2 RXRG RXRG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa)
AGRPAgouti related neuropeptide. (136 aa)
TRADDTNFRSF1A associated via death domain. (309 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
POMCProopiomelanocortin. (258 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
ACACBAcetyl-CoA carboxylase beta. (2172 aa)
STAT3Signal transducer and activator of transcription. (796 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (682 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ACSBG2Acyl-CoA synthetase bubblegum family member 2. (667 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (235 aa)
ADIPOR1Adiponectin receptor 1. (375 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
ACSL1Acyl-CoA synthetase long chain family member 1. (664 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
TNFRSF1BTNF receptor superfamily member 1B. (449 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
NFKBIENFKB inhibitor epsilon. (434 aa)
CPT1CCarnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family. (802 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
CPT1BCarnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
LEPRLeptin receptor. (1055 aa)
NFKBIBNFKB inhibitor beta. (346 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
NPYNeuropeptide Y. (97 aa)
ADIPOR2Adiponectin receptor 2. (325 aa)
NFKB1Nuclear factor kappa B subunit 1. (961 aa)
RXRBRetinoid X receptor beta. (535 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa)
RXRARetinoid X receptor alpha. (469 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (331 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
ACSL5Acyl-CoA synthetase long chain family member 5. (683 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (442 aa)
SLC2A3MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (496 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2. (587 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (495 aa)
MAPK9Mitogen-activated protein kinase 9. (417 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2536 aa)
ENSPCOP00000000328Uncharacterized protein. (67 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (697 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (540 aa)
MAPK8Mitogen-activated protein kinase 8. (346 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
TNFRSF1ATNF receptor superfamily member 1A. (447 aa)
PRKAA2Non-specific serine/threonine protein kinase. (553 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (490 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (707 aa)
ACSBG1Acyl-CoA synthetase bubblegum family member 1. (723 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (711 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
ACSL6AMP-binding domain-containing protein. (705 aa)
MAPK10Mitogen-activated protein kinase. (473 aa)
PPARGC1APPARG coactivator 1 alpha. (809 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (747 aa)
ACSL3Acyl-CoA synthetase long chain family member 3. (673 aa)
IRS2Insulin receptor substrate 2. (1335 aa)
RXRGRetinoid X receptor gamma. (463 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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