STRINGSTRING
PGAM1 PGAM1 ENSPCOP00000008641 ENSPCOP00000008641 CREB3L2 CREB3L2 FBP1 FBP1 SLC2A2 SLC2A2 ENSPCOP00000007681 ENSPCOP00000007681 CAMK2B CAMK2B PRKAB2 PRKAB2 ENSPCOP00000006746 ENSPCOP00000006746 SIK1 SIK1 PRKACB PRKACB PPP4R3B PPP4R3B PRKAG1 PRKAG1 PRMT1 PRMT1 PLCB1 PLCB1 PPP3CA PPP3CA PPP4C PPP4C ENSPCOP00000004635 ENSPCOP00000004635 ENSPCOP00000003860 ENSPCOP00000003860 ITPR2 ITPR2 SIK2 SIK2 PHKG2 PHKG2 PRKAB1 PRKAB1 PFKL PFKL ARSI ARSI ENSPCOP00000002207 ENSPCOP00000002207 SLC2A1 SLC2A1 FBP2 FBP2 ENSPCOP00000001921 ENSPCOP00000001921 PYGM PYGM ADCY2 ADCY2 ENSPCOP00000000328 ENSPCOP00000000328 ENSPCOP00000000307 ENSPCOP00000000307 CPT1A CPT1A GCGR GCGR ENSPCOP00000031755 ENSPCOP00000031755 GNAS GNAS PARP8 PARP8 PFKP PFKP PCK1 PCK1 ACACB ACACB PLCB3 PLCB3 ENSPCOP00000030058 ENSPCOP00000030058 G6PC G6PC AKT1 AKT1 GYS2 GYS2 PRKACA PRKACA FAP FAP AKT3 AKT3 PRKAG2 PRKAG2 PPP4R3A PPP4R3A GYS1 GYS1 SIRT1 SIRT1 PCK2 PCK2 PRKAA2 PRKAA2 PLCB4 PLCB4 ENSPCOP00000026464 ENSPCOP00000026464 ATF2 ATF2 CREB3L1 CREB3L1 CREB3 CREB3 PPP3CB PPP3CB ITPR1 ITPR1 CAMK2A CAMK2A ENSPCOP00000024532 ENSPCOP00000024532 PKM PKM PRKAA1 PRKAA1 LDHB LDHB CREB5 CREB5 CAMK2G CAMK2G PHKB PHKB PFKM PFKM CAMK2D CAMK2D PPARGC1A PPARGC1A PDE3B PDE3B ENSPCOP00000021134 ENSPCOP00000021134 CREBBP CREBBP PHKG1 PHKG1 PPP3R1 PPP3R1 ENSPCOP00000020173 ENSPCOP00000020173 CRTC2 CRTC2 G6PC2 G6PC2 GCK GCK EP300 EP300 TNIK TNIK AKT2 AKT2 PYGB PYGB CREB1 CREB1 ITPR3 ITPR3 PHKA2 PHKA2 ATF4 ATF4 PRKAG3 PRKAG3 CALML4 CALML4 PDHA1 PDHA1 PFKFB1 PFKFB1 PHKA1 PHKA1 PYGL PYGL CREB3L4 CREB3L4 G6PC3 G6PC3 PVALEF PVALEF ACACA ACACA PLCB2 PLCB2 PDHB PDHB CALM2 CALM2 PPP3CC PPP3CC CPT1C CPT1C CREB3L3 CREB3L3 FOXO1 FOXO1 LOC105817330 LOC105817330 LOC105822391 LOC105822391 PPARA PPARA CPT1B CPT1B CALM3 CALM3 ENSPCOP00000010764 ENSPCOP00000010764 PARP6 PARP6 GCG GCG ENSPCOP00000009899 ENSPCOP00000009899 CALM1 CALM1 PGAM2 PGAM2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PGAM1Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
ENSPCOP00000008641Uncharacterized protein. (715 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (508 aa)
FBP1FBPase domain-containing protein; Belongs to the FBPase class 1 family. (338 aa)
SLC2A2Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (524 aa)
ENSPCOP00000007681EF-hand domain-containing protein. (132 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (665 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa)
ENSPCOP00000006746Uncharacterized protein. (188 aa)
SIK1Uncharacterized protein. (777 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (399 aa)
PPP4R3BProtein phosphatase 4 regulatory subunit 3B. (820 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (331 aa)
PRMT1Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
PLCB1Phosphoinositide phospholipase C. (1010 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
PPP4CSerine/threonine-protein phosphatase. (307 aa)
ENSPCOP00000004635L-lactate dehydrogenase. (233 aa)
ENSPCOP00000003860Ldh_1_C domain-containing protein. (87 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2702 aa)
SIK2Salt inducible kinase 2. (890 aa)
PHKG2Phosphorylase kinase catalytic subunit gamma 2; Belongs to the protein kinase superfamily. (406 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
PFKLPhosphofructokinase, liver type. (687 aa)
ARSIArylsulfatase family member I. (572 aa)
ENSPCOP00000002207Uncharacterized protein; Belongs to the calmodulin family. (113 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (495 aa)
FBP2Fructose-bisphosphatase 2; Belongs to the FBPase class 1 family. (339 aa)
ENSPCOP00000001921L-lactate dehydrogenase. (273 aa)
PYGMAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa)
ADCY2Adenylate cyclase 2. (904 aa)
ENSPCOP00000000328Uncharacterized protein. (67 aa)
ENSPCOP00000000307Uncharacterized protein; Belongs to the calmodulin family. (142 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (697 aa)
GCGRGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (485 aa)
ENSPCOP00000031755Uncharacterized protein; Belongs to the LDH/MDH superfamily. (324 aa)
GNASUncharacterized protein. (394 aa)
PARP8Poly [ADP-ribose] polymerase. (784 aa)
PFKPPhosphofructokinase, platelet. (751 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
ACACBAcetyl-CoA carboxylase beta. (2172 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
ENSPCOP00000030058Uncharacterized protein. (55 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
GYS2Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (450 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (540 aa)
PPP4R3AProtein phosphatase 4 regulatory subunit 3A. (716 aa)
GYS1Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (738 aa)
SIRT1Sirtuin 1. (743 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
PRKAA2Non-specific serine/threonine protein kinase. (553 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1197 aa)
ENSPCOP00000026464Uncharacterized protein. (46 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (520 aa)
CREB3cAMP responsive element binding protein 3. (373 aa)
PPP3CBSerine/threonine-protein phosphatase. (531 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2732 aa)
CAMK2AProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (471 aa)
ENSPCOP00000024532Uncharacterized protein; Belongs to the calmodulin family. (142 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
LDHBLdh_1_N domain-containing protein. (252 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (600 aa)
PHKBPhosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1066 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (858 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (503 aa)
PPARGC1APPARG coactivator 1 alpha. (809 aa)
PDE3BPhosphodiesterase. (1047 aa)
ENSPCOP00000021134E1_dh domain-containing protein. (188 aa)
CREBBPCREB binding protein. (2449 aa)
PHKG1Phosphorylase kinase catalytic subunit gamma 1; Belongs to the protein kinase superfamily. (389 aa)
PPP3R1Uncharacterized protein. (189 aa)
ENSPCOP00000020173Ldh_1_C domain-containing protein. (58 aa)
CRTC2CREB regulated transcription coactivator 2. (686 aa)
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
GCKPhosphotransferase. (466 aa)
EP300E1A binding protein p300. (2424 aa)
TNIKTRAF2 and NCK interacting kinase. (1363 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (843 aa)
CREB1cAMP responsive element binding protein 1. (280 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2664 aa)
PHKA2Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1235 aa)
ATF4Activating transcription factor 4. (351 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa)
CALML4Calmodulin like 4. (178 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (387 aa)
PFKFB16-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (471 aa)
PHKA1Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1029 aa)
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (851 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (395 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
PVALEFParvalbumin like EF-hand containing. (126 aa)
ACACAAcetyl-CoA carboxylase alpha. (2347 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (138 aa)
PPP3CCSerine/threonine-protein phosphatase. (520 aa)
CPT1CCarnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family. (802 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (456 aa)
FOXO1Forkhead box O1. (656 aa)
LOC105817330L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (324 aa)
LOC105822391FBPase domain-containing protein; Belongs to the FBPase class 1 family. (278 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
CPT1BCarnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
CALM3Calmodulin 1; Belongs to the calmodulin family. (149 aa)
ENSPCOP00000010764EF-hand domain-containing protein; Belongs to the calmodulin family. (109 aa)
PARP6Poly [ADP-ribose] polymerase. (631 aa)
GCGGlucagon. (180 aa)
ENSPCOP00000009899L-lactate dehydrogenase. (243 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (150 aa)
PGAM2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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