STRINGSTRING
PIK3CA PIK3CA ARR3 ARR3 PIK3CD PIK3CD PLCB3 PLCB3 MAPK1 MAPK1 PRKCB PRKCB PRKCA PRKCA AKT1 AKT1 AKT3 AKT3 KCNN2 KCNN2 KCNJ6 KCNJ6 PLCB4 PLCB4 CACNA1F CACNA1F ITPR1 ITPR1 ARRB2 ARRB2 CACNA1H CACNA1H GNRH1 GNRH1 KCNJ3 KCNJ3 CACNA1S CACNA1S HRAS HRAS HCN3 HCN3 AKT2 AKT2 ITPR3 ITPR3 PIK3R1 PIK3R1 PIK3R2 PIK3R2 ARRB1 ARRB1 CACNA1G CACNA1G GABBR1 GABBR1 CACNA1C CACNA1C KISS1 KISS1 PIK3CB PIK3CB GABBR2 GABBR2 MAP2K1 MAP2K1 ENSPCOP00000015906 ENSPCOP00000015906 CACNA1I CACNA1I KISS1R KISS1R PLCB2 PLCB2 KCNN4 KCNN4 CACNA1D CACNA1D CSDE1 CSDE1 ENSPCOP00000012404 ENSPCOP00000012404 KCNJ5 KCNJ5 TRPC4 TRPC4 KCNJ9 KCNJ9 TRPC5 TRPC5 KRAS KRAS ENSPCOP00000009588 ENSPCOP00000009588 ENSPCOP00000009091 ENSPCOP00000009091 MAPK3 MAPK3 PIK3R3 PIK3R3 KCNN3 KCNN3 PLCB1 PLCB1 NRAS NRAS RAF1 RAF1 KCNN1 KCNN1 ESR2 ESR2 TRPC1 TRPC1 ITPR2 ITPR2 KCNJ11 KCNJ11 ENSPCOP00000002686 ENSPCOP00000002686 SPP1 SPP1 PRKCG PRKCG MAP2K2 MAP2K2 LOC105809276 LOC105809276
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3CAPhosphatidylinositol 3-kinase catalytic subunit type 3. (933 aa)
ARR3Arrestin 3. (390 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
PRKCAUncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (575 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (840 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (423 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1197 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1973 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2732 aa)
ARRB2Arrestin beta 2. (441 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2221 aa)
GNRH1Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (92 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1544 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (779 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2664 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PIK3R2Uncharacterized protein. (726 aa)
ARRB1Arrestin beta 1. (429 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2381 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (962 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2016 aa)
KISS1KiSS-1 metastasis suppressor. (176 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (941 aa)
MAP2K1Mitogen-activated protein kinase kinase 1. (377 aa)
ENSPCOP00000015906Uncharacterized protein. (105 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (1991 aa)
KISS1RKISS1 receptor. (398 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
KCNN4Potassium calcium-activated channel subfamily N member 4. (427 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2180 aa)
CSDE1Cold shock domain containing E1. (798 aa)
ENSPCOP00000012404Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (125 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (982 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (393 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
KRASUncharacterized protein. (75 aa)
ENSPCOP00000009588Uncharacterized protein. (316 aa)
ENSPCOP00000009091Uncharacterized protein. (291 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
PIK3R3Uncharacterized protein. (454 aa)
KCNN3Potassium calcium-activated channel subfamily N member 3. (734 aa)
PLCB1Phosphoinositide phospholipase C. (1010 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
KCNN1Potassium calcium-activated channel subfamily N member 1. (543 aa)
ESR2Estrogen receptor 2. (471 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (842 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2702 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
ENSPCOP00000002686CSD_1 domain-containing protein. (293 aa)
SPP1Secreted phosphoprotein 1. (305 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
LOC105809276Cys_knot domain-containing protein. (146 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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