(45 nodes) Fat digestion and absorption network (Propithecus coquereli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APOA1	Apolipoprotein A1. (265 aa)
	ACAT2	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
	FABP1	FABP domain-containing protein. (69 aa)
	APOA4	Apolipoprotein A4. (384 aa)
	PLPP2	Phospholipid phosphatase 2. (304 aa)
	PNLIP	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (436 aa)
	SLC27A4	Solute carrier family 27 member 4. (643 aa)
	ENSPCOP00000006033	Phospholipase A(2). (94 aa)
	SCARB1	Scavenger receptor class B member 1; Belongs to the CD36 family. (461 aa)
	LIPK	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (399 aa)
	PLA2G10	Phospholipase A(2). (165 aa)
	AGPAT2	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (278 aa)
	ABCA1	ATP binding cassette subfamily A member 1. (2240 aa)
	SLC27A1	Solute carrier family 27 member 1. (646 aa)
	PLPP1	Phospholipid phosphatase 1. (286 aa)
	CD36	CD36 molecule; Belongs to the CD36 family. (472 aa)
	PNLIPRP2	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (403 aa)
	MOGAT2	Monoacylglycerol O-acyltransferase 2. (334 aa)
	PLA2G2D	Phospholipase A(2). (132 aa)
	PLA2G12B	Phospholipase A2 group XIIB. (195 aa)
	ENSPCOP00000013692	Uncharacterized protein. (88 aa)
	DGAT2	Diacylglycerol O-acyltransferase 2. (388 aa)
	DGAT1	O-acyltransferase. (490 aa)
	LIPJ	Lipase family member J. (365 aa)
	MTTP	Microsomal triglyceride transfer protein. (776 aa)
	APOB	Apolipoprotein B. (4538 aa)
	ABCG8	ATP binding cassette subfamily G member 8. (673 aa)
	CLPS	Colipase. (112 aa)
	ACAT1	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa)
	PLPP3	acidPPc domain-containing protein. (312 aa)
	AGPAT1	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (287 aa)
	ENSPCOP00000024427	Uncharacterized protein. (173 aa)
	GOT2	Aspartate aminotransferase. (370 aa)
	PLA2G12A	Phospholipase A2 group XIIA. (182 aa)
	MOGAT3	Monoacylglycerol O-acyltransferase 3. (341 aa)
	ABCG5	ATP binding cassette subfamily G member 5. (652 aa)
	PLA2G2C	Phospholipase A(2). (139 aa)
	FABP2	Fatty acid binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	LIPF	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (401 aa)
	NPC1L1	NPC1 like intracellular cholesterol transporter 1. (1324 aa)
	PLA2G3	Phospholipase A2 group III. (506 aa)
	PNLIPRP1	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (447 aa)
	PLA2G2F	Phospholipase A(2). (210 aa)
	PLA2G5	Phospholipase A(2). (138 aa)
	PLA2G2E	Phospholipase A(2). (142 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA1	APOA1	ENSPCOP00000007481	ENSPCOP00000003211	ATP binding cassette subfamily A member 1.	Apolipoprotein A1.	0.853
ABCA1	APOB	ENSPCOP00000007481	ENSPCOP00000019340	ATP binding cassette subfamily A member 1.	Apolipoprotein B.	0.507
ABCA1	CD36	ENSPCOP00000007481	ENSPCOP00000010616	ATP binding cassette subfamily A member 1.	CD36 molecule; Belongs to the CD36 family.	0.616
ABCA1	NPC1L1	ENSPCOP00000007481	ENSPCOP00000029573	ATP binding cassette subfamily A member 1.	NPC1 like intracellular cholesterol transporter 1.	0.474
ABCA1	SCARB1	ENSPCOP00000007481	ENSPCOP00000006165	ATP binding cassette subfamily A member 1.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.562
ABCG5	ABCG8	ENSPCOP00000026933	ENSPCOP00000019636	ATP binding cassette subfamily G member 5.	ATP binding cassette subfamily G member 8.	0.999
ABCG5	APOA1	ENSPCOP00000026933	ENSPCOP00000003211	ATP binding cassette subfamily G member 5.	Apolipoprotein A1.	0.466
ABCG5	APOB	ENSPCOP00000026933	ENSPCOP00000019340	ATP binding cassette subfamily G member 5.	Apolipoprotein B.	0.468
ABCG5	MTTP	ENSPCOP00000026933	ENSPCOP00000018337	ATP binding cassette subfamily G member 5.	Microsomal triglyceride transfer protein.	0.461
ABCG5	NPC1L1	ENSPCOP00000026933	ENSPCOP00000029573	ATP binding cassette subfamily G member 5.	NPC1 like intracellular cholesterol transporter 1.	0.619
ABCG5	SCARB1	ENSPCOP00000026933	ENSPCOP00000006165	ATP binding cassette subfamily G member 5.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.407
ABCG8	ABCG5	ENSPCOP00000019636	ENSPCOP00000026933	ATP binding cassette subfamily G member 8.	ATP binding cassette subfamily G member 5.	0.999
ABCG8	APOA1	ENSPCOP00000019636	ENSPCOP00000003211	ATP binding cassette subfamily G member 8.	Apolipoprotein A1.	0.466
ABCG8	APOB	ENSPCOP00000019636	ENSPCOP00000019340	ATP binding cassette subfamily G member 8.	Apolipoprotein B.	0.437
ABCG8	NPC1L1	ENSPCOP00000019636	ENSPCOP00000029573	ATP binding cassette subfamily G member 8.	NPC1 like intracellular cholesterol transporter 1.	0.597
ABCG8	SCARB1	ENSPCOP00000019636	ENSPCOP00000006165	ATP binding cassette subfamily G member 8.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.400
ACAT1	ACAT2	ENSPCOP00000022693	ENSPCOP00000003897	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.888
ACAT1	SLC27A1	ENSPCOP00000022693	ENSPCOP00000007640	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Solute carrier family 27 member 1.	0.605
ACAT2	ACAT1	ENSPCOP00000003897	ENSPCOP00000022693	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.888
ACAT2	SLC27A1	ENSPCOP00000003897	ENSPCOP00000007640	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	Solute carrier family 27 member 1.	0.605