(57 nodes) Mineral absorption network (Propithecus coquereli)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

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protein homology

Your Input:
	ATP2B3	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
	PGPEP1	Pyroglutamyl-peptidase I. (209 aa)
	LOC105820863	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
	ATP2B2	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
	ATP7A	ATPase copper transporting alpha. (1502 aa)
	SLC8A2	Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (926 aa)
	ATP1B4	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (352 aa)
	LOC105820865	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
	SLC40A1	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (573 aa)
	CELSR3	Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family. (3313 aa)
	FTL	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (175 aa)
	TF	Transferrin; Belongs to the transferrin family. (697 aa)
	SLC5A1	Solute carrier family 5 member 1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (664 aa)
	SLC5A4	Solute carrier family 5 member 4; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (655 aa)
	HMOX2	Heme oxygenase 2. (328 aa)
	TRPM7	Transient receptor potential cation channel subfamily M member 7. (1683 aa)
	SLC9A5	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (896 aa)
	SLC46A1	Solute carrier family 46 member 1. (459 aa)
	ATP1A2	Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
	ATP1B2	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
	SLC34A3	Solute carrier family 34 member 3. (600 aa)
	SLC30A1	Solute carrier family 30 member 1. (510 aa)
	ATP1A4	Sodium/potassium-transporting ATPase subunit alpha. (1031 aa)
	LOC105820864	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
	LTF	Lactotransferrin; Belongs to the transferrin family. (708 aa)
	SLC39A4	Solute carrier family 39 member 4. (651 aa)
	HMOX1	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
	FXYD2	FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (66 aa)
	SLC26A9	Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (791 aa)
	ATP2B1	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1258 aa)
	SLC26A3	Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (759 aa)
	SLC6A19	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (634 aa)
	SLC34A1	Solute carrier family 34 member 1. (639 aa)
	SLC34A2	Solute carrier family 34 member 2. (695 aa)
	SLC9A3	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (834 aa)
	SLC31A1	Solute carrier family 31 member 1. (198 aa)
	LOC105820862	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
	SLC26A6	Solute carrier family 26 member 6. (757 aa)
	ATOX1	Antioxidant 1 copper chaperone. (72 aa)
	STEAP2	STEAP2 metalloreductase. (415 aa)
	ATP1B1	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
	ATP1A1	Sodium/potassium-transporting ATPase subunit alpha. (1023 aa)
	SLC8A1	Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (974 aa)
	VDR	Vitamin D receptor. (474 aa)
	SLC11A2	Uncharacterized protein. (590 aa)
	HEPH	Hephaestin; Belongs to the multicopper oxidase family. (1201 aa)
	ATP2B4	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1204 aa)
	TRPM6	Transient receptor potential cation channel subfamily M member 6. (1892 aa)
	STEAP1	Ferric oxidoreductase domain-containing protein. (339 aa)
	SLC8A3	Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
	CYBRD1	Cytochrome b reductase 1. (286 aa)
	ATP7B	ATPase copper transporting beta. (1460 aa)
	S100G	S100 calcium binding protein G. (79 aa)
	ATP1A3	Sodium/potassium-transporting ATPase subunit alpha. (1080 aa)
	ATP1B3	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
	LOC105815021	Uncharacterized protein. (567 aa)
	CLCN2	Chloride channel protein. (902 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATOX1	ATP7A	ENSPCOP00000011868	ENSPCOP00000022605	Antioxidant 1 copper chaperone.	ATPase copper transporting alpha.	0.990
ATOX1	ATP7B	ENSPCOP00000011868	ENSPCOP00000017855	Antioxidant 1 copper chaperone.	ATPase copper transporting beta.	0.988
ATOX1	CLCN2	ENSPCOP00000011868	ENSPCOP00000019785	Antioxidant 1 copper chaperone.	Chloride channel protein.	0.574
ATOX1	FTL	ENSPCOP00000011868	ENSPCOP00000026750	Antioxidant 1 copper chaperone.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.410
ATOX1	SLC31A1	ENSPCOP00000011868	ENSPCOP00000010685	Antioxidant 1 copper chaperone.	Solute carrier family 31 member 1.	0.567
ATOX1	TRPM6	ENSPCOP00000011868	ENSPCOP00000014233	Antioxidant 1 copper chaperone.	Transient receptor potential cation channel subfamily M member 6.	0.597
ATOX1	TRPM7	ENSPCOP00000011868	ENSPCOP00000030735	Antioxidant 1 copper chaperone.	Transient receptor potential cation channel subfamily M member 7.	0.504
ATP1A1	ATP1A3	ENSPCOP00000012242	ENSPCOP00000018625	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.904
ATP1A1	ATP1A4	ENSPCOP00000012242	ENSPCOP00000007562	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.855
ATP1A1	ATP1B1	ENSPCOP00000012242	ENSPCOP00000012223	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.989
ATP1A1	ATP1B2	ENSPCOP00000012242	ENSPCOP00000032107	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.951
ATP1A1	ATP1B3	ENSPCOP00000012242	ENSPCOP00000018983	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.950
ATP1A1	ATP1B4	ENSPCOP00000012242	ENSPCOP00000024061	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.938
ATP1A1	ATP7A	ENSPCOP00000012242	ENSPCOP00000022605	Sodium/potassium-transporting ATPase subunit alpha.	ATPase copper transporting alpha.	0.581
ATP1A1	ATP7B	ENSPCOP00000012242	ENSPCOP00000017855	Sodium/potassium-transporting ATPase subunit alpha.	ATPase copper transporting beta.	0.581
ATP1A1	FXYD2	ENSPCOP00000012242	ENSPCOP00000003648	Sodium/potassium-transporting ATPase subunit alpha.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.983
ATP1A2	ATP1A3	ENSPCOP00000031602	ENSPCOP00000018625	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.904
ATP1A2	ATP1A4	ENSPCOP00000031602	ENSPCOP00000007562	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.855
ATP1A2	ATP1B1	ENSPCOP00000031602	ENSPCOP00000012223	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.989
ATP1A2	ATP1B2	ENSPCOP00000031602	ENSPCOP00000032107	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.951