STRINGSTRING
DNM2 DNM2 ENSPCOP00000032098 ENSPCOP00000032098 SHC1 SHC1 ENSPCOP00000031413 ENSPCOP00000031413 ELMO2 ELMO2 LOC105810942 LOC105810942 SEPTIN1 SEPTIN1 CTNNA1 CTNNA1 PIK3CD PIK3CD CEP152 CEP152 SLC25A1 SLC25A1 CRKL CRKL ARHGAP10 ARHGAP10 DNM1 DNM1 ELMO1 ELMO1 ELMO3 ELMO3 ENSPCOP00000027946 ENSPCOP00000027946 CAV2 CAV2 PTK2 PTK2 ENSPCOP00000025645 ENSPCOP00000025645 SEPTIN3 SEPTIN3 CAV1 CAV1 FN1 FN1 WASL WASL SEPTIN6 SEPTIN6 CTNNB1 CTNNB1 ARPC5 ARPC5 CDC42 CDC42 ENSPCOP00000022134 ENSPCOP00000022134 ACTG1 ACTG1 CTNNA3 CTNNA3 MET MET SEPTIN9 SEPTIN9 SHC3 SHC3 LOC105824234 LOC105824234 LOC105811778 LOC105811778 SRC SRC PIK3R1 PIK3R1 PIK3R2 PIK3R2 CRK CRK SEPTIN8 SEPTIN8 CLTCL1 CLTCL1 PIK3CB PIK3CB CLTA CLTA PIK3CA PIK3CA ILK ILK CTNNA2 CTNNA2 SHC2 SHC2 GAB1 GAB1 WASF2 WASF2 ARPC4 ARPC4 PXN PXN CD2AP CD2AP CBL CBL RHOC RHOC ARPC3 ARPC3 ACTL8 ACTL8 MAD2L2 MAD2L2 CDH1 CDH1 PIK3R3 PIK3R3 SHC4 SHC4 GOLGA2 GOLGA2 SEPTIN11 SEPTIN11 CLTB CLTB RHOA RHOA VCL VCL DNM3 DNM3 ITGA5 ITGA5 SEPTIN12 SEPTIN12 ARPC5L ARPC5L ARPC1A ARPC1A ACTB ACTB ENSPCOP00000004655 ENSPCOP00000004655 CAV3 CAV3 ARHGEF26 ARHGEF26 WASF1 WASF1 CTTN CTTN ARPC1B ARPC1B RHOG RHOG CLTC CLTC ENSPCOP00000002927 ENSPCOP00000002927 ITGB1 ITGB1 ARPC2 ARPC2 TMEM250 TMEM250 ENSPCOP00000000994 ENSPCOP00000000994 BCAR1 BCAR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
ENSPCOP00000032098Uncharacterized protein. (226 aa)
SHC1SHC adaptor protein 1. (582 aa)
ENSPCOP00000031413Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (72 aa)
ELMO2Engulfment and cell motility 2. (720 aa)
LOC105810942WD_REPEATS_REGION domain-containing protein. (347 aa)
SEPTIN1Septin 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (406 aa)
CTNNA1Catenin alpha 1. (906 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
CEP152Centrosomal protein 152. (1655 aa)
SLC25A1Solute carrier family 25 member 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (223 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
ARHGAP10Rho GTPase activating protein 10. (768 aa)
DNM1Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
ELMO3Engulfment and cell motility 3. (748 aa)
ENSPCOP00000027946Uncharacterized protein. (298 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
PTK2Protein tyrosine kinase 2. (1089 aa)
ENSPCOP00000025645Uncharacterized protein. (162 aa)
SEPTIN3Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (358 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
FN1Fibronectin 1. (2290 aa)
WASLWASP like actin nucleation promoting factor. (505 aa)
SEPTIN6Septin 6; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (434 aa)
CTNNB1Catenin beta 1. (781 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (126 aa)
CDC42Uncharacterized protein. (191 aa)
ENSPCOP00000022134Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (452 aa)
ACTG1Actin gamma 1. (404 aa)
CTNNA3Catenin alpha 3. (783 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1397 aa)
SEPTIN9Septin 9; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (586 aa)
SHC3SHC adaptor protein 3. (596 aa)
LOC105824234Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (303 aa)
LOC105811778WD_REPEATS_REGION domain-containing protein. (354 aa)
SRCTyrosine-protein kinase. (543 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PIK3R2Uncharacterized protein. (726 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
SEPTIN8Septin 8; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (591 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1426 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa)
PIK3CAPhosphatidylinositol 3-kinase catalytic subunit type 3. (933 aa)
ILKIntegrin linked kinase. (518 aa)
CTNNA2Catenin alpha 2. (822 aa)
SHC2Uncharacterized protein. (578 aa)
GAB1GRB2 associated binding protein 1. (683 aa)
WASF2WASP family member 2. (497 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (186 aa)
PXNPaxillin. (1073 aa)
CD2APCD2 associated protein. (534 aa)
CBLCbl proto-oncogene. (891 aa)
RHOCRas homolog family member C. (193 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
ACTL8Actin like 8; Belongs to the actin family. (351 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (235 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (904 aa)
PIK3R3Uncharacterized protein. (454 aa)
SHC4SHC adaptor protein 4. (630 aa)
GOLGA2Uncharacterized protein. (926 aa)
SEPTIN11Septin 11; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (439 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (229 aa)
RHOARas homolog family member A. (193 aa)
VCLVinculin. (1134 aa)
DNM3Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (869 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1041 aa)
SEPTIN12Septin 12; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (358 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
ARPC1AUncharacterized protein. (188 aa)
ACTBActin beta. (378 aa)
ENSPCOP00000004655WD_REPEATS_REGION domain-containing protein. (262 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (872 aa)
WASF1WASP family member 1. (559 aa)
CTTNCortactin. (550 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (372 aa)
RHOGRas homolog family member G. (191 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1681 aa)
ENSPCOP00000002927Uncharacterized protein. (160 aa)
ITGB1Integrin beta. (585 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (292 aa)
TMEM250Transmembrane protein 250. (139 aa)
ENSPCOP00000000994Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (173 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (902 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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