STRINGSTRING
CLK1 CLK1 ENSPCOP00000023228 ENSPCOP00000023228 CLK3 CLK3 ENSPCOP00000021800 ENSPCOP00000021800 CD14 CD14 ENSPCOP00000021423 ENSPCOP00000021423 ENSPCOP00000021188 ENSPCOP00000021188 HSF5 HSF5 ENSPCOP00000019409 ENSPCOP00000019409 ENSPCOP00000019371 ENSPCOP00000019371 SAR1A SAR1A CASP7 CASP7 ENSPCOP00000017794 ENSPCOP00000017794 CASP3 CASP3 APAF1 APAF1 HBS1L HBS1L VCP VCP IL12A IL12A LOC105817207 LOC105817207 TNF TNF BNIP3 BNIP3 CASP1 CASP1 LOC105825403 LOC105825403 NFKBIA NFKBIA LOC105819867 LOC105819867 HSF1 HSF1 ENSPCOP00000023440 ENSPCOP00000023440 ENSPCOP00000013079 ENSPCOP00000013079 EEF1A2 EEF1A2 C7orf31 C7orf31 C3 C3 IL12B IL12B ENSPCOP00000012148 ENSPCOP00000012148 RAB1A RAB1A IL1B IL1B ENSPCOP00000009238 ENSPCOP00000009238 EEF1G EEF1G CLK4 CLK4 IL6 IL6 NFKB1 NFKB1 HSPA8 HSPA8 ITGB2 ITGB2 LOC105810602 LOC105810602 HSPA2 HSPA2 HSPA6 HSPA6 SEC22B SEC22B HSPD1 HSPD1 HSPA1L HSPA1L SAR1B SAR1B ENSPCOP00000004684 ENSPCOP00000004684 ENSPCOP00000003911 ENSPCOP00000003911 CR1 CR1 LOC105817206 LOC105817206 CASP8 CASP8 ENSPCOP00000024480 ENSPCOP00000024480 NFKB2 NFKB2 CXCL8 CXCL8 LOC105817729 LOC105817729 RAB1B RAB1B ENSPCOP00000027105 ENSPCOP00000027105 LOC105807375 LOC105807375 TLR4 TLR4 ARF1 ARF1 HSF4 HSF4 METRN METRN ENSPCOP00000028694 ENSPCOP00000028694 CASP9 CASP9 CLK2 CLK2 OTUD3 OTUD3 ENSPCOP00000029778 ENSPCOP00000029778 MYD88 MYD88 PYCARD PYCARD METRNL METRNL LOC105815609 LOC105815609 RELA RELA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CLK1CDC like kinase 1. (523 aa)
ENSPCOP00000023228Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (99 aa)
CLK3CDC like kinase 3. (638 aa)
ENSPCOP00000021800Uncharacterized protein. (175 aa)
CD14Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (375 aa)
ENSPCOP00000021423HSF_DOMAIN domain-containing protein. (201 aa)
ENSPCOP00000021188Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (151 aa)
HSF5Heat shock transcription factor 5. (611 aa)
ENSPCOP00000019409Uncharacterized protein; Belongs to the heat shock protein 70 family. (568 aa)
ENSPCOP00000019371Uncharacterized protein; Belongs to the heat shock protein 70 family. (554 aa)
SAR1ASecretion associated Ras related GTPase 1A; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (341 aa)
ENSPCOP00000017794Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (84 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
APAF1Apoptotic peptidase activating factor 1. (1204 aa)
HBS1LHBS1_N domain-containing protein. (632 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
LOC105817207Tr-type G domain-containing protein. (446 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (235 aa)
BNIP3Uncharacterized protein. (235 aa)
CASP1Uncharacterized protein; Belongs to the peptidase C14A family. (254 aa)
LOC105825403Tr-type G domain-containing protein. (446 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
LOC105819867Tr-type G domain-containing protein. (408 aa)
HSF1Heat shock transcription factor 1. (531 aa)
ENSPCOP00000023440Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (95 aa)
ENSPCOP00000013079Uncharacterized protein. (80 aa)
EEF1A2Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (458 aa)
C7orf31Chromosome 7 open reading frame 31. (589 aa)
C3Complement C3. (1551 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (326 aa)
ENSPCOP00000012148Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (153 aa)
RAB1ARAB1A, member RAS oncogene family. (207 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
ENSPCOP00000009238Tr-type G domain-containing protein. (65 aa)
EEF1GEukaryotic translation elongation factor 1 gamma. (437 aa)
CLK4CDC like kinase 4; Belongs to the protein kinase superfamily. (436 aa)
IL6Uncharacterized protein. (211 aa)
NFKB1Nuclear factor kappa B subunit 1. (961 aa)
HSPA8Uncharacterized protein; Belongs to the heat shock protein 70 family. (650 aa)
ITGB2Integrin beta. (764 aa)
LOC105810602Tr-type G domain-containing protein. (399 aa)
HSPA2Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (601 aa)
HSPA6Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family. (643 aa)
SEC22BSEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family. (215 aa)
HSPD1Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (610 aa)
HSPA1LHeat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (641 aa)
SAR1BUncharacterized protein. (176 aa)
ENSPCOP00000004684Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSPCOP00000003911Tr-type G domain-containing protein. (67 aa)
CR1Uncharacterized protein. (1529 aa)
LOC105817206Tr-type G domain-containing protein. (446 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (395 aa)
ENSPCOP00000024480Uncharacterized protein. (103 aa)
NFKB2Nuclear factor kappa B subunit 2. (895 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
LOC105817729Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
RAB1BRAB1B, member RAS oncogene family. (201 aa)
ENSPCOP00000027105Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC105807375Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (840 aa)
ARF1ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
HSF4Heat shock transcription factor 4. (461 aa)
METRNMeteorin, glial cell differentiation regulator. (290 aa)
ENSPCOP00000028694Uncharacterized protein. (47 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (406 aa)
CLK2CDC like kinase 2; Belongs to the protein kinase superfamily. (500 aa)
OTUD3OTU deubiquitinase 3. (398 aa)
ENSPCOP00000029778Tr-type G domain-containing protein. (64 aa)
MYD88MYD88 innate immune signal transduction adaptor. (353 aa)
PYCARDPYD and CARD domain containing. (195 aa)
METRNLMeteorin like, glial cell differentiation regulator. (311 aa)
LOC105815609Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (100 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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