STRINGSTRING
PRKCG PRKCG TSC1 TSC1 LOC105822640 LOC105822640 ENSPCOP00000002148 ENSPCOP00000002148 ENSPCOP00000002207 ENSPCOP00000002207 ENSPCOP00000002211 ENSPCOP00000002211 ADCY6 ADCY6 ENSPCOP00000002686 ENSPCOP00000002686 PTGER2 PTGER2 CCL5 CCL5 IL10RA IL10RA MYC MYC ITPR2 ITPR2 GNGT2 GNGT2 STING1 STING1 ENSPCOP00000004684 ENSPCOP00000004684 CXCR2 CXCR2 GNG10 GNG10 RAF1 RAF1 NRAS NRAS GNB2 GNB2 PPP3CA PPP3CA PLCB1 PLCB1 IRF3 IRF3 ENSPCOP00000005894 ENSPCOP00000005894 GNG8 GNG8 PRKACB PRKACB RHOA RHOA CXCL12 CXCL12 ENSPCOP00000006977 ENSPCOP00000006977 TAP2 TAP2 ENSPCOP00000007290 ENSPCOP00000007290 GNAI1 GNAI1 LOC105812775 LOC105812775 ENSPCOP00000007681 ENSPCOP00000007681 ROCK1 ROCK1 PIK3R3 PIK3R3 NFKB1 NFKB1 IL6 IL6 MAPK3 MAPK3 CREB3L2 CREB3L2 E2F3 E2F3 ENSPCOP00000008641 ENSPCOP00000008641 CCL2 CCL2 PTGS2 PTGS2 NFATC4 NFATC4 SOS1 SOS1 RHEB RHEB LOC105819868 LOC105819868 ENSPCOP00000009588 ENSPCOP00000009588 RAC2 RAC2 KRAS KRAS CALM1 CALM1 SOS2 SOS2 ARHGEF1 ARHGEF1 ITGAV ITGAV ENSPCOP00000010764 ENSPCOP00000010764 PTGER1 PTGER1 RHOC RHOC RB1 RB1 IL1B IL1B PTGER3 PTGER3 CALM3 CALM3 ADCY1 ADCY1 ADCY4 ADCY4 ROCK2 ROCK2 LOC105813852 LOC105813852 ADCY8 ADCY8 CREB3L3 CREB3L3 CSDE1 CSDE1 PXN PXN GNG3 GNG3 C7orf31 C7orf31 TAPBP TAPBP PPP3CC PPP3CC JAK1 JAK1 ENSPCOP00000013454 ENSPCOP00000013454 LOC105812777 LOC105812777 RPS6KB2 RPS6KB2 CALM2 CALM2 MAPK12 MAPK12 NFKBIA NFKBIA PLCB2 PLCB2 LOC105817910 LOC105817910 MAPK11 MAPK11 GNB5 GNB5 TRAF2 TRAF2 TAP1 TAP1 TNF TNF PVALEF PVALEF NFATC2 NFATC2 PIK3CA PIK3CA LOC105823863 LOC105823863 CREB3L4 CREB3L4 MAP2K1 MAP2K1 TSC2 TSC2 PIK3CB PIK3CB TRADD TRADD TBK1 TBK1 ADCY3 ADCY3 BAK1 BAK1 RAC1 RAC1 MAPK14 MAPK14 PDIA3 PDIA3 CALML4 CALML4 CASP3 CASP3 GRB2 GRB2 ATF6B ATF6B ATF4 ATF4 CGAS CGAS E2F1 E2F1 EIF4EBP1 EIF4EBP1 EGFR EGFR CRK CRK PIK3R2 PIK3R2 PIK3R1 PIK3R1 SRC SRC ITPR3 ITPR3 CREB1 CREB1 GNA12 GNA12 AKT2 AKT2 GNB1 GNB1 BAX BAX HRAS HRAS CX3CL1 CX3CL1 PPP3R1 PPP3R1 IKBKB IKBKB GNG11 GNG11 PTGER4 PTGER4 FADD FADD GNB4 GNB4 CREB5 CREB5 B2M B2M CTNNB1 CTNNB1 GSK3B GSK3B ENSPCOP00000023228 ENSPCOP00000023228 ENSPCOP00000023440 ENSPCOP00000023440 GNG13 GNG13 ENSPCOP00000023702 ENSPCOP00000023702 CASP8 CASP8 ARHGEF11 ARHGEF11 GNG2 GNG2 CXCR4 CXCR4 VEGFA VEGFA ADCY7 ADCY7 ADCY9 ADCY9 RIPK1 RIPK1 ENSPCOP00000024532 ENSPCOP00000024532 GNA13 GNA13 CXCL8 CXCL8 LOC105817846 LOC105817846 ITPR1 ITPR1 PPP3CB PPP3CB MAP2K6 MAP2K6 ENSPCOP00000025645 ENSPCOP00000025645 CREB3 CREB3 PTK2 PTK2 FASLG FASLG CREB3L1 CREB3L1 RHEBL1 RHEBL1 ATF2 ATF2 ENSPCOP00000026249 ENSPCOP00000026249 PDGFRA PDGFRA CDKN2A CDKN2A CDK6 CDK6 PLCB4 PLCB4 SP1 SP1 ENSPCOP00000027105 ENSPCOP00000027105 IKBKG IKBKG LOC105807375 LOC105807375 TNFRSF1A TNFRSF1A PTK2B PTK2B CCL4 CCL4 ENSPCOP00000028434 ENSPCOP00000028434 AKAP13 AKAP13 AKT3 AKT3 PRKACA PRKACA AKT1 AKT1 CALR CALR IL6R IL6R CASP9 CASP9 PRKCA PRKCA PRKCB PRKCB CCND1 CCND1 CHUK CHUK LOC105817290 LOC105817290 ADCY5 ADCY5 MAPK1 MAPK1 CRKL CRKL GNAI2 GNAI2 STAT3 STAT3 PLCB3 PLCB3 PIK3CD PIK3CD MAPK13 MAPK13 GNAO1 GNAO1 RPS6KB1 RPS6KB1 TRAF5 TRAF5 GNG7 GNG7 GNAS GNAS TP53 TP53 ENSPCOP00000031946 ENSPCOP00000031946 LOC105815609 LOC105815609 GNB3 GNB3 BID BID RELA RELA ARHGEF12 ARHGEF12 BCAR1 BCAR1 E2F2 E2F2 ELK1 ELK1 PTRHD1 PTRHD1 NFATC1 NFATC1 GNG12 GNG12 GNG4 GNG4 FAS FAS MAP2K2 MAP2K2 ENSPCOP00000000307 ENSPCOP00000000307 ADCY2 ADCY2 LOC105817288 LOC105817288 RAC3 RAC3 IL1R1 IL1R1 NFATC3 NFATC3 MTOR MTOR CDK4 CDK4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
TSC1TSC complex subunit 1. (1164 aa)
LOC105822640Integrin beta; Belongs to the integrin beta chain family. (454 aa)
ENSPCOP00000002148Uncharacterized protein. (118 aa)
ENSPCOP00000002207Uncharacterized protein; Belongs to the calmodulin family. (113 aa)
ENSPCOP00000002211Ig-like domain-containing protein; Belongs to the MHC class I family. (389 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1167 aa)
ENSPCOP00000002686CSD_1 domain-containing protein. (293 aa)
PTGER2Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (361 aa)
CCL5C-C motif chemokine. (91 aa)
IL10RAInterleukin 10 receptor subunit alpha. (578 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (453 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2702 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
STING1Transmembrane protein 173. (374 aa)
ENSPCOP00000004684Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
CXCR2C-X-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (359 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
GNB2G protein subunit beta 2. (340 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
PLCB1Phosphoinositide phospholipase C. (1010 aa)
IRF3IRF tryptophan pentad repeat domain-containing protein. (419 aa)
ENSPCOP00000005894Uncharacterized protein. (192 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (399 aa)
RHOARas homolog family member A. (193 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (159 aa)
ENSPCOP00000006977IRF-3 domain-containing protein. (275 aa)
TAP2Uncharacterized protein. (724 aa)
ENSPCOP00000007290Uncharacterized protein. (174 aa)
GNAI1G protein subunit alpha i1. (354 aa)
LOC105812775SWIB domain-containing protein. (243 aa)
ENSPCOP00000007681EF-hand domain-containing protein. (132 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1316 aa)
PIK3R3Uncharacterized protein. (454 aa)
NFKB1Nuclear factor kappa B subunit 1. (961 aa)
IL6Uncharacterized protein. (211 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (508 aa)
E2F3E2F transcription factor 3. (464 aa)
ENSPCOP00000008641Uncharacterized protein. (715 aa)
CCL2C-C motif chemokine. (99 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
NFATC4Nuclear factor of activated T cells 4. (953 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
RHEBRas homolog, mTORC1 binding. (184 aa)
LOC105819868Protein kinase domain-containing protein. (302 aa)
ENSPCOP00000009588Uncharacterized protein. (316 aa)
RAC2Rac family small GTPase 2. (192 aa)
KRASUncharacterized protein. (75 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (150 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (882 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (967 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1047 aa)
ENSPCOP00000010764EF-hand domain-containing protein; Belongs to the calmodulin family. (109 aa)
PTGER1Prostaglandin E receptor 1. (405 aa)
RHOCRas homolog family member C. (193 aa)
RB1RB transcriptional corepressor 1. (787 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
PTGER3Prostaglandin E receptor 3. (390 aa)
CALM3Calmodulin 1; Belongs to the calmodulin family. (149 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1361 aa)
LOC105813852C-C motif chemokine. (94 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1229 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (456 aa)
CSDE1Cold shock domain containing E1. (798 aa)
PXNPaxillin. (1073 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
C7orf31Chromosome 7 open reading frame 31. (589 aa)
TAPBPTAP binding protein. (482 aa)
PPP3CCSerine/threonine-protein phosphatase. (520 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
ENSPCOP00000013454Ig-like domain-containing protein; Belongs to the MHC class I family. (365 aa)
LOC105812777Uncharacterized protein. (436 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (487 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (138 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
LOC105817910Ig-like domain-containing protein; Belongs to the MHC class I family. (363 aa)
MAPK11Mitogen-activated protein kinase. (443 aa)
GNB5G protein subunit beta 5. (395 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
TAP1Transporter 1, ATP binding cassette subfamily B member. (794 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (235 aa)
PVALEFParvalbumin like EF-hand containing. (126 aa)
NFATC2Nuclear factor of activated T cells 2. (925 aa)
PIK3CAPhosphatidylinositol 3-kinase catalytic subunit type 3. (933 aa)
LOC105823863Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (395 aa)
MAP2K1Mitogen-activated protein kinase kinase 1. (377 aa)
TSC2TSC complex subunit 2. (1814 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
TRADDTNFRSF1A associated via death domain. (309 aa)
TBK1TANK binding kinase 1. (690 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
RAC1Rac family small GTPase 1. (211 aa)
MAPK14Mitogen-activated protein kinase 14. (340 aa)
PDIA3Protein disulfide-isomerase. (506 aa)
CALML4Calmodulin like 4. (178 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
ATF6BActivating transcription factor 6 beta. (702 aa)
ATF4Activating transcription factor 4. (351 aa)
CGASCyclic GMP-AMP synthase. (523 aa)
E2F1E2F transcription factor 1. (436 aa)
EIF4EBP1Uncharacterized protein. (118 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
PIK3R2Uncharacterized protein. (726 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
SRCTyrosine-protein kinase. (543 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2664 aa)
CREB1cAMP responsive element binding protein 1. (280 aa)
GNA12G protein subunit alpha 12. (380 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
GNB1G protein subunit beta 1. (334 aa)
BAXBCL2 associated X, apoptosis regulator. (199 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (405 aa)
PPP3R1Uncharacterized protein. (189 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (747 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (205 aa)
GNB4G protein subunit beta 4. (321 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (120 aa)
CTNNB1Catenin beta 1. (781 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (390 aa)
ENSPCOP00000023228Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (99 aa)
ENSPCOP00000023440Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (95 aa)
GNG13G protein subunit gamma 13. (67 aa)
ENSPCOP00000023702Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (61 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (395 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (1556 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (109 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (352 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (643 aa)
ENSPCOP00000024532Uncharacterized protein; Belongs to the calmodulin family. (142 aa)
GNA13G protein subunit alpha 13. (377 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
LOC105817846Ig-like domain-containing protein; Belongs to the MHC class I family. (373 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2732 aa)
PPP3CBSerine/threonine-protein phosphatase. (531 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (345 aa)
ENSPCOP00000025645Uncharacterized protein. (162 aa)
CREB3cAMP responsive element binding protein 3. (373 aa)
PTK2Protein tyrosine kinase 2. (1089 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (278 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (520 aa)
RHEBL1RHEB like 1. (183 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
ENSPCOP00000026249Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (79 aa)
PDGFRAPlatelet derived growth factor receptor alpha; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1027 aa)
CDKN2ACyclin dependent kinase inhibitor 2A. (152 aa)
CDK6Cyclin dependent kinase 6. (263 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1197 aa)
SP1Sp1 transcription factor. (788 aa)
ENSPCOP00000027105Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (490 aa)
LOC105807375Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
TNFRSF1ATNF receptor superfamily member 1A. (447 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (967 aa)
CCL4C-C motif chemokine. (92 aa)
ENSPCOP00000028434RUN domain-containing protein. (177 aa)
AKAP13A-kinase anchoring protein 13. (2786 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
CALRCalreticulin. (417 aa)
IL6RInterleukin 6 receptor. (469 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (406 aa)
PRKCAUncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (575 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (682 aa)
LOC105817290Ig-like domain-containing protein; Belongs to the MHC class I family. (464 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1258 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
GNAI2G protein subunit alpha i2. (355 aa)
STAT3Signal transducer and activator of transcription. (796 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
GNAO1G protein subunit alpha o1. (354 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (502 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (536 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNASUncharacterized protein. (394 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa)
ENSPCOP00000031946G protein gamma domain-containing protein. (68 aa)
LOC105815609Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (100 aa)
GNB3G protein subunit beta 3. (340 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (220 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1496 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (902 aa)
E2F2E2F transcription factor 2. (435 aa)
ELK1ETS transcription factor ELK1. (430 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
NFATC1Nuclear factor of activated T cells 1. (945 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
FASFas cell surface death receptor. (309 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
ENSPCOP00000000307Uncharacterized protein; Belongs to the calmodulin family. (142 aa)
ADCY2Adenylate cyclase 2. (904 aa)
LOC105817288Ig-like domain-containing protein; Belongs to the MHC class I family. (371 aa)
RAC3Rac family small GTPase 3. (205 aa)
IL1R1Interleukin 1 receptor type 1. (516 aa)
NFATC3Nuclear factor of activated T cells 3. (1075 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2536 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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