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PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) | ||||
TSC1 | TSC complex subunit 1. (1164 aa) | ||||
LOC105822640 | Integrin beta; Belongs to the integrin beta chain family. (454 aa) | ||||
ENSPCOP00000002148 | Uncharacterized protein. (118 aa) | ||||
ENSPCOP00000002207 | Uncharacterized protein; Belongs to the calmodulin family. (113 aa) | ||||
ENSPCOP00000002211 | Ig-like domain-containing protein; Belongs to the MHC class I family. (389 aa) | ||||
ADCY6 | Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1167 aa) | ||||
ENSPCOP00000002686 | CSD_1 domain-containing protein. (293 aa) | ||||
PTGER2 | Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (361 aa) | ||||
CCL5 | C-C motif chemokine. (91 aa) | ||||
IL10RA | Interleukin 10 receptor subunit alpha. (578 aa) | ||||
MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (453 aa) | ||||
ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2702 aa) | ||||
GNGT2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa) | ||||
STING1 | Transmembrane protein 173. (374 aa) | ||||
ENSPCOP00000004684 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
CXCR2 | C-X-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (359 aa) | ||||
GNG10 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) | ||||
RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) | ||||
NRAS | NRAS proto-oncogene, GTPase. (189 aa) | ||||
GNB2 | G protein subunit beta 2. (340 aa) | ||||
PPP3CA | Serine/threonine-protein phosphatase. (521 aa) | ||||
PLCB1 | Phosphoinositide phospholipase C. (1010 aa) | ||||
IRF3 | IRF tryptophan pentad repeat domain-containing protein. (419 aa) | ||||
ENSPCOP00000005894 | Uncharacterized protein. (192 aa) | ||||
GNG8 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa) | ||||
PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (399 aa) | ||||
RHOA | Ras homolog family member A. (193 aa) | ||||
CXCL12 | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (159 aa) | ||||
ENSPCOP00000006977 | IRF-3 domain-containing protein. (275 aa) | ||||
TAP2 | Uncharacterized protein. (724 aa) | ||||
ENSPCOP00000007290 | Uncharacterized protein. (174 aa) | ||||
GNAI1 | G protein subunit alpha i1. (354 aa) | ||||
LOC105812775 | SWIB domain-containing protein. (243 aa) | ||||
ENSPCOP00000007681 | EF-hand domain-containing protein. (132 aa) | ||||
ROCK1 | Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1316 aa) | ||||
PIK3R3 | Uncharacterized protein. (454 aa) | ||||
NFKB1 | Nuclear factor kappa B subunit 1. (961 aa) | ||||
IL6 | Uncharacterized protein. (211 aa) | ||||
MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) | ||||
CREB3L2 | cAMP responsive element binding protein 3 like 2. (508 aa) | ||||
E2F3 | E2F transcription factor 3. (464 aa) | ||||
ENSPCOP00000008641 | Uncharacterized protein. (715 aa) | ||||
CCL2 | C-C motif chemokine. (99 aa) | ||||
PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) | ||||
NFATC4 | Nuclear factor of activated T cells 4. (953 aa) | ||||
SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa) | ||||
RHEB | Ras homolog, mTORC1 binding. (184 aa) | ||||
LOC105819868 | Protein kinase domain-containing protein. (302 aa) | ||||
ENSPCOP00000009588 | Uncharacterized protein. (316 aa) | ||||
RAC2 | Rac family small GTPase 2. (192 aa) | ||||
KRAS | Uncharacterized protein. (75 aa) | ||||
CALM1 | Calmodulin 1; Belongs to the calmodulin family. (150 aa) | ||||
SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (882 aa) | ||||
ARHGEF1 | Rho guanine nucleotide exchange factor 1. (967 aa) | ||||
ITGAV | Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1047 aa) | ||||
ENSPCOP00000010764 | EF-hand domain-containing protein; Belongs to the calmodulin family. (109 aa) | ||||
PTGER1 | Prostaglandin E receptor 1. (405 aa) | ||||
RHOC | Ras homolog family member C. (193 aa) | ||||
RB1 | RB transcriptional corepressor 1. (787 aa) | ||||
IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa) | ||||
PTGER3 | Prostaglandin E receptor 3. (390 aa) | ||||
CALM3 | Calmodulin 1; Belongs to the calmodulin family. (149 aa) | ||||
ADCY1 | Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa) | ||||
ADCY4 | Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa) | ||||
ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1361 aa) | ||||
LOC105813852 | C-C motif chemokine. (94 aa) | ||||
ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1229 aa) | ||||
CREB3L3 | cAMP responsive element binding protein 3 like 3. (456 aa) | ||||
CSDE1 | Cold shock domain containing E1. (798 aa) | ||||
PXN | Paxillin. (1073 aa) | ||||
GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) | ||||
C7orf31 | Chromosome 7 open reading frame 31. (589 aa) | ||||
TAPBP | TAP binding protein. (482 aa) | ||||
PPP3CC | Serine/threonine-protein phosphatase. (520 aa) | ||||
JAK1 | Tyrosine-protein kinase. (1153 aa) | ||||
ENSPCOP00000013454 | Ig-like domain-containing protein; Belongs to the MHC class I family. (365 aa) | ||||
LOC105812777 | Uncharacterized protein. (436 aa) | ||||
RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (487 aa) | ||||
CALM2 | Calmodulin 2; Belongs to the calmodulin family. (138 aa) | ||||
MAPK12 | Mitogen-activated protein kinase. (367 aa) | ||||
NFKBIA | NFKB inhibitor alpha. (314 aa) | ||||
PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa) | ||||
LOC105817910 | Ig-like domain-containing protein; Belongs to the MHC class I family. (363 aa) | ||||
MAPK11 | Mitogen-activated protein kinase. (443 aa) | ||||
GNB5 | G protein subunit beta 5. (395 aa) | ||||
TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) | ||||
TAP1 | Transporter 1, ATP binding cassette subfamily B member. (794 aa) | ||||
TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (235 aa) | ||||
PVALEF | Parvalbumin like EF-hand containing. (126 aa) | ||||
NFATC2 | Nuclear factor of activated T cells 2. (925 aa) | ||||
PIK3CA | Phosphatidylinositol 3-kinase catalytic subunit type 3. (933 aa) | ||||
LOC105823863 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) | ||||
CREB3L4 | cAMP responsive element binding protein 3 like 4. (395 aa) | ||||
MAP2K1 | Mitogen-activated protein kinase kinase 1. (377 aa) | ||||
TSC2 | TSC complex subunit 2. (1814 aa) | ||||
PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) | ||||
TRADD | TNFRSF1A associated via death domain. (309 aa) | ||||
TBK1 | TANK binding kinase 1. (690 aa) | ||||
ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa) | ||||
BAK1 | BCL2 antagonist/killer 1. (211 aa) | ||||
RAC1 | Rac family small GTPase 1. (211 aa) | ||||
MAPK14 | Mitogen-activated protein kinase 14. (340 aa) | ||||
PDIA3 | Protein disulfide-isomerase. (506 aa) | ||||
CALML4 | Calmodulin like 4. (178 aa) | ||||
CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) | ||||
GRB2 | Growth factor receptor bound protein 2. (217 aa) | ||||
ATF6B | Activating transcription factor 6 beta. (702 aa) | ||||
ATF4 | Activating transcription factor 4. (351 aa) | ||||
CGAS | Cyclic GMP-AMP synthase. (523 aa) | ||||
E2F1 | E2F transcription factor 1. (436 aa) | ||||
EIF4EBP1 | Uncharacterized protein. (118 aa) | ||||
EGFR | Receptor protein-tyrosine kinase. (1210 aa) | ||||
CRK | CRK proto-oncogene, adaptor protein. (304 aa) | ||||
PIK3R2 | Uncharacterized protein. (726 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) | ||||
SRC | Tyrosine-protein kinase. (543 aa) | ||||
ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2664 aa) | ||||
CREB1 | cAMP responsive element binding protein 1. (280 aa) | ||||
GNA12 | G protein subunit alpha 12. (380 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
GNB1 | G protein subunit beta 1. (334 aa) | ||||
BAX | BCL2 associated X, apoptosis regulator. (199 aa) | ||||
HRAS | HRas proto-oncogene, GTPase. (189 aa) | ||||
CX3CL1 | C-X3-C motif chemokine ligand 1. (405 aa) | ||||
PPP3R1 | Uncharacterized protein. (189 aa) | ||||
IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (747 aa) | ||||
GNG11 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa) | ||||
PTGER4 | Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa) | ||||
FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (205 aa) | ||||
GNB4 | G protein subunit beta 4. (321 aa) | ||||
CREB5 | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa) | ||||
B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (120 aa) | ||||
CTNNB1 | Catenin beta 1. (781 aa) | ||||
GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (390 aa) | ||||
ENSPCOP00000023228 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (99 aa) | ||||
ENSPCOP00000023440 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (95 aa) | ||||
GNG13 | G protein subunit gamma 13. (67 aa) | ||||
ENSPCOP00000023702 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (61 aa) | ||||
CASP8 | Caspase 8; Belongs to the peptidase C14A family. (395 aa) | ||||
ARHGEF11 | Rho guanine nucleotide exchange factor 11. (1556 aa) | ||||
GNG2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (109 aa) | ||||
CXCR4 | C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (352 aa) | ||||
VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa) | ||||
ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa) | ||||
ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa) | ||||
RIPK1 | Receptor interacting serine/threonine kinase 1. (643 aa) | ||||
ENSPCOP00000024532 | Uncharacterized protein; Belongs to the calmodulin family. (142 aa) | ||||
GNA13 | G protein subunit alpha 13. (377 aa) | ||||
CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) | ||||
LOC105817846 | Ig-like domain-containing protein; Belongs to the MHC class I family. (373 aa) | ||||
ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2732 aa) | ||||
PPP3CB | Serine/threonine-protein phosphatase. (531 aa) | ||||
MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (345 aa) | ||||
ENSPCOP00000025645 | Uncharacterized protein. (162 aa) | ||||
CREB3 | cAMP responsive element binding protein 3. (373 aa) | ||||
PTK2 | Protein tyrosine kinase 2. (1089 aa) | ||||
FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (278 aa) | ||||
CREB3L1 | cAMP responsive element binding protein 3 like 1. (520 aa) | ||||
RHEBL1 | RHEB like 1. (183 aa) | ||||
ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) | ||||
ENSPCOP00000026249 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (79 aa) | ||||
PDGFRA | Platelet derived growth factor receptor alpha; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1027 aa) | ||||
CDKN2A | Cyclin dependent kinase inhibitor 2A. (152 aa) | ||||
CDK6 | Cyclin dependent kinase 6. (263 aa) | ||||
PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1197 aa) | ||||
SP1 | Sp1 transcription factor. (788 aa) | ||||
ENSPCOP00000027105 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (490 aa) | ||||
LOC105807375 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
TNFRSF1A | TNF receptor superfamily member 1A. (447 aa) | ||||
PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (967 aa) | ||||
CCL4 | C-C motif chemokine. (92 aa) | ||||
ENSPCOP00000028434 | RUN domain-containing protein. (177 aa) | ||||
AKAP13 | A-kinase anchoring protein 13. (2786 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) | ||||
CALR | Calreticulin. (417 aa) | ||||
IL6R | Interleukin 6 receptor. (469 aa) | ||||
CASP9 | Caspase 9; Belongs to the peptidase C14A family. (406 aa) | ||||
PRKCA | Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (575 aa) | ||||
PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) | ||||
CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) | ||||
CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (682 aa) | ||||
LOC105817290 | Ig-like domain-containing protein; Belongs to the MHC class I family. (464 aa) | ||||
ADCY5 | Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1258 aa) | ||||
MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) | ||||
CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) | ||||
GNAI2 | G protein subunit alpha i2. (355 aa) | ||||
STAT3 | Signal transducer and activator of transcription. (796 aa) | ||||
PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa) | ||||
PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) | ||||
MAPK13 | Mitogen-activated protein kinase. (365 aa) | ||||
GNAO1 | G protein subunit alpha o1. (354 aa) | ||||
RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (502 aa) | ||||
TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (536 aa) | ||||
GNG7 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) | ||||
GNAS | Uncharacterized protein. (394 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa) | ||||
ENSPCOP00000031946 | G protein gamma domain-containing protein. (68 aa) | ||||
LOC105815609 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (100 aa) | ||||
GNB3 | G protein subunit beta 3. (340 aa) | ||||
BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (220 aa) | ||||
RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) | ||||
ARHGEF12 | Rho guanine nucleotide exchange factor 12. (1496 aa) | ||||
BCAR1 | BCAR1 scaffold protein, Cas family member. (902 aa) | ||||
E2F2 | E2F transcription factor 2. (435 aa) | ||||
ELK1 | ETS transcription factor ELK1. (430 aa) | ||||
PTRHD1 | Peptidyl-tRNA hydrolase domain containing 1. (140 aa) | ||||
NFATC1 | Nuclear factor of activated T cells 1. (945 aa) | ||||
GNG12 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) | ||||
GNG4 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) | ||||
FAS | Fas cell surface death receptor. (309 aa) | ||||
MAP2K2 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa) | ||||
ENSPCOP00000000307 | Uncharacterized protein; Belongs to the calmodulin family. (142 aa) | ||||
ADCY2 | Adenylate cyclase 2. (904 aa) | ||||
LOC105817288 | Ig-like domain-containing protein; Belongs to the MHC class I family. (371 aa) | ||||
RAC3 | Rac family small GTPase 3. (205 aa) | ||||
IL1R1 | Interleukin 1 receptor type 1. (516 aa) | ||||
NFATC3 | Nuclear factor of activated T cells 3. (1075 aa) | ||||
MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2536 aa) | ||||
CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |