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| | PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (502 aa) |
| | BMP2K | Protein kinase domain-containing protein. (616 aa) |
| | PBX4 | PBX homeobox 4. (374 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (796 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa) |
| | KLF3 | Kruppel like factor 3. (343 aa) |
| | CSF2 | Colony stimulating factor 2. (146 aa) |
| | SIX1 | SIX homeobox 1. (284 aa) |
| | GRIA3 | Glutamate ionotropic receptor AMPA type subunit 3. (894 aa) |
| | LOC105821782 | Uncharacterized protein. (380 aa) |
| | BCL6 | BCL6 transcription repressor. (706 aa) |
| | ENSPCOP00000009525 | ETS domain-containing protein. (186 aa) |
| | GZMH | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (248 aa) |
| | TLX3 | T cell leukemia homeobox 3. (291 aa) |
| | MEF2C | Myocyte enhancer factor 2C. (483 aa) |
| | EYA1 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa) |
| | JMJD1C | Jumonji domain containing 1C. (2544 aa) |
| | WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | IL6 | Uncharacterized protein. (211 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (961 aa) |
| | PBX1 | PBX homeobox 1. (430 aa) |
| | HOXA10 | Homeobox A10. (410 aa) |
| | PRCC | Proline rich mitotic checkpoint control factor. (490 aa) |
| | HOXC11 | Homeobox C11. (369 aa) |
| | HOXD11 | Homeobox D11. (339 aa) |
| | RXRB | Retinoid X receptor beta. (535 aa) |
| | PLAT | Plasminogen activator; Belongs to the peptidase S1 family. (563 aa) |
| | LOC105812775 | SWIB domain-containing protein. (243 aa) |
| | IL1R2 | Interleukin 1 receptor type 2. (424 aa) |
| | RXRA | Retinoid X receptor alpha. (469 aa) |
| | LDB1 | LIM domain binding 1. (411 aa) |
| | MLLT1 | MLLT1 super elongation complex subunit. (551 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | ITGB7 | Integrin beta; Belongs to the integrin beta chain family. (797 aa) |
| | SMAD1 | Mothers against decapentaplegic homolog. (465 aa) |
| | MLLT3 | MLLT3 super elongation complex subunit. (569 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) |
| | MYCN | MYCN proto-oncogene, bHLH transcription factor. (464 aa) |
| | GADD45B | Growth arrest and DNA damage inducible beta. (160 aa) |
| | ENSPCOP00000004787 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (445 aa) |
| | PAX7 | Paired box 7. (484 aa) |
| | ENSPCOP00000004369 | Histone domain-containing protein. (136 aa) |
| | NR4A3 | Nuclear receptor subfamily 4 group A member 3. (645 aa) |
| | LOC105821917 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | RUNX2 | RUNX family transcription factor 2. (539 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (453 aa) |
| | ENSPCOP00000003606 | annotation not available (136 aa) |
| | BIRC3 | Baculoviral IAP repeat containing 3. (597 aa) |
| | SUPT3H | SPT3 homolog, SAGA and STAGA complex component. (328 aa) |
| | HHEX | Hematopoietically expressed homeobox. (271 aa) |
| | ENSPCOP00000002664 | RRM domain-containing protein. (599 aa) |
| | SIN3B | SIN3 transcription regulator family member B. (1156 aa) |
| | TAF15 | TATA-box binding protein associated factor 15. (584 aa) |
| | ETV4 | ETS variant 4. (485 aa) |
| | BCL2A1 | BCL2 related protein A1. (173 aa) |
| | LOC105805653 | Histone H3.1. (136 aa) |
| | LOC105805676 | Histone H3.1. (136 aa) |
| | LOC105817995 | Histone domain-containing protein. (136 aa) |
| | ENSPCOP00000001816 | Uncharacterized protein. (61 aa) |
| | MEIS2 | Meis homeobox 2. (477 aa) |
| | ENSPCOP00000001451 | annotation not available (136 aa) |
| | ZBTB16 | Zinc finger and BTB domain containing 16. (673 aa) |
| | ENSPCOP00000001375 | annotation not available (136 aa) |
| | DUSP6 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | ENSPCOP00000001292 | annotation not available (136 aa) |
| | ZBTB17 | Zinc finger and BTB domain containing 17. (798 aa) |
| | LOC105812697 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | ENSPCOP00000000819 | annotation not available (136 aa) |
| | LMO2 | LIM domain only 2. (223 aa) |
| | HMGA2 | Uncharacterized protein. (117 aa) |
| | LOC105805701 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | ENSPCOP00000000601 | Uncharacterized protein. (104 aa) |
| | TLX1 | T cell leukemia homeobox 1. (261 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | IGFBP3 | Insulin like growth factor binding protein 3. (293 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa) |
| | KDM6A | Lysine demethylase 6A. (1454 aa) |
| | PER2 | Period circadian regulator 2. (1265 aa) |
| | HPGD | 15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa) |
| | ENSPCOP00000030367 | Ig-like domain-containing protein. (214 aa) |
| | POLK | DNA polymerase kappa. (832 aa) |
| | TCF3 | Transcription factor 3. (655 aa) |
| | TFE3 | Transcription factor binding to IGHM enhancer 3. (576 aa) |
| | LYL1 | LYL1 basic helix-loop-helix family member. (279 aa) |
| | AFF1 | AF4/FMR2 family member 1. (1186 aa) |
| | ID2 | Inhibitor of DNA binding 2. (134 aa) |
| | ETV6 | ETS variant 6. (452 aa) |
| | TRAF1 | TNF receptor-associated factor. (415 aa) |
| | H3F3A | Histone domain-containing protein. (137 aa) |
| | CEBPB | CCAAT/enhancer-binding protein. (347 aa) |
| | ELK4 | ETS transcription factor ELK4. (432 aa) |
| | LOC105805675 | Histone H3.1. (136 aa) |
| | H3-4 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | H3F3C | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | LOC105805725 | Histone H3.1. (136 aa) |
| | ARNT2 | Aryl hydrocarbon receptor nuclear translocator 2. (717 aa) |
| | MEIS1 | Meis homeobox 1. (463 aa) |
| | MITF | Melanocyte inducing transcription factor. (526 aa) |
| | GZMB | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (269 aa) |
| | FEV | FEV transcription factor, ETS family member. (239 aa) |
| | SPIB | ETS domain-containing protein. (262 aa) |
| | SPI1 | Spi-1 proto-oncogene. (272 aa) |
| | NUPR1 | Nuclear protein 1, transcriptional regulator. (82 aa) |
| | PLAU | Plasminogen activator, urokinase. (432 aa) |
| | SP1 | Sp1 transcription factor. (788 aa) |
| | LOC105813903 | Uncharacterized protein. (577 aa) |
| | CSF1R | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (964 aa) |
| | FLI1 | Fli-1 proto-oncogene, ETS transcription factor. (452 aa) |
| | ATF1 | Activating transcription factor 1. (270 aa) |
| | CD40 | CD40 molecule. (281 aa) |
| | ELANE | Elastase, neutrophil expressed; Belongs to the peptidase S1 family. (268 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (442 aa) |
| | PTK2 | Protein tyrosine kinase 2. (1089 aa) |
| | NCOR1 | Nuclear receptor corepressor 1. (2432 aa) |
| | SIX2 | SIX homeobox 2. (296 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) |
| | CCNT1 | Cyclin T1; Belongs to the cyclin family. (724 aa) |
| | EWSR1 | Uncharacterized protein. (692 aa) |
| | MLF1 | Myeloid leukemia factor 1. (282 aa) |
| | PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | FLT3 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (949 aa) |
| | ASPSCR1 | ASPSCR1 tether for SLC2A4, UBX domain containing. (550 aa) |
| | CCNT2 | Cyclin T2; Belongs to the cyclin family. (733 aa) |
| | SIX4 | SIX homeobox 4. (782 aa) |
| | RARA | Retinoic acid receptor alpha. (472 aa) |
| | CDK9 | Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa) |
| | PBX3 | PBX homeobox 3. (434 aa) |
| | MAX | MYC associated factor X. (160 aa) |
| | REL | REL proto-oncogene, NF-kB subunit. (592 aa) |
| | DDX5 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa) |
| | MMP3 | Matrix metallopeptidase 3. (477 aa) |
| | NFKBIZ | NFKB inhibitor zeta. (715 aa) |
| | GADD45A | Growth arrest and DNA damage inducible alpha. (165 aa) |
| | ENSPCOP00000022032 | Ig-like domain-containing protein. (95 aa) |
| | MET | MET proto-oncogene, receptor tyrosine kinase. (1397 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1350 aa) |
| | CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (375 aa) |
| | H3F3B | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (619 aa) |
| | TSPAN7 | Tetraspanin. (265 aa) |
| | PAX5 | Paired box 5. (391 aa) |
| | FUT8 | Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. (536 aa) |
| | BCL2L1 | BCL2 like 1. (233 aa) |
| | FUS | FUS RNA binding protein. (445 aa) |
| | DDB2 | Damage specific DNA binding protein 2. (426 aa) |
| | PML | Promyelocytic leukemia. (887 aa) |
| | RXRG | Retinoid X receptor gamma. (463 aa) |
| | GADD45G | Growth arrest and DNA damage inducible gamma. (161 aa) |
| | CD86 | CD86 molecule. (336 aa) |
| | BMI1 | RING-type domain-containing protein. (326 aa) |
| | ZEB1 | Zinc finger E-box binding homeobox 1. (1002 aa) |
| | PTCRA | Pre T cell antigen receptor alpha. (259 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (199 aa) |
| | DOT1L | Histone-lysine N-methyltransferase, H3 lysine-79 specific. (1511 aa) |
| | IGF1 | Insulin like growth factor 1. (208 aa) |
| | BAIAP3 | BAI1 associated protein 3. (1016 aa) |
| | PAX3 | Paired box 3. (486 aa) |
| | LOC105811621 | DEFENSIN domain-containing protein. (94 aa) |
| | MEN1 | Menin 1. (616 aa) |
| | PBX2 | PBX homeobox 2. (430 aa) |
| | SPINT1 | Serine peptidase inhibitor, Kunitz type 1. (511 aa) |
| | TMPRSS2 | Transmembrane serine protease 2; Belongs to the peptidase S1 family. (541 aa) |
| | ATM | ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2635 aa) |
| | MAF | MAF bZIP transcription factor. (242 aa) |
| | WT1 | WT1 transcription factor. (522 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | KMT2A | Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3967 aa) |
| | FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa) |
| | NSD2 | Nuclear receptor binding SET domain protein 2. (1364 aa) |
| | PAX8 | Paired box 8. (458 aa) |
| | SIN3A | SIN3 transcription regulator family member A. (1274 aa) |
| | MPO | Myeloperoxidase. (742 aa) |
| | ETV1 | ETS variant 1. (471 aa) |
| | PAX2 | Paired box 2. (417 aa) |
| | HOXA9 | Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (272 aa) |
| | CDKN2C | Cyclin dependent kinase inhibitor 2C. (168 aa) |
| | CEBPE | CCAAT/enhancer-binding protein. (281 aa) |
| | BCL11B | BAF chromatin remodeling complex subunit BCL11B. (896 aa) |
| | ENSPCOP00000014952 | PBC domain-containing protein. (120 aa) |
| | HOXA11 | Homeobox A11. (316 aa) |
| | LOC105822770 | Ig-like domain-containing protein. (140 aa) |
| | NGFR | Nerve growth factor receptor. (429 aa) |
| | RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (478 aa) |
| | RUNX1T1 | RUNX1 partner transcriptional co-repressor 1. (660 aa) |
| | ENSPCOP00000014061 | Peptidase S1 domain-containing protein. (113 aa) |
| | LOC105812777 | Uncharacterized protein. (436 aa) |
| | IL2RB | Interleukin 2 receptor subunit beta. (558 aa) |
| | PROM1 | Prominin 1. (866 aa) |
| | ERG | ETS transcription factor ERG. (486 aa) |
| | JUP | Junction plakoglobin. (745 aa) |
| | FOXO1 | Forkhead box O1. (656 aa) |
| | MMP9 | Matrix metallopeptidase 9. (709 aa) |
| | MMP10 | Matrix metallopeptidase 10; Belongs to the peptidase M10A family. (287 aa) |
| | SLC45A3 | Solute carrier family 45 member 3. (553 aa) |
