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CTNNB1 | Catenin beta 1. (781 aa) | ||||
FLNB | Filamin B. (2633 aa) | ||||
SLC9A1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa) | ||||
HPSE | Heparanase. (395 aa) | ||||
DROSHA | Drosha ribonuclease III. (1354 aa) | ||||
WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (332 aa) | ||||
RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (502 aa) | ||||
FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (394 aa) | ||||
MAPK13 | Mitogen-activated protein kinase. (365 aa) | ||||
IGF2 | Insulin like growth factor 2. (236 aa) | ||||
WNT2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa) | ||||
PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) | ||||
STAT3 | Signal transducer and activator of transcription. (796 aa) | ||||
MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) | ||||
WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa) | ||||
CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) | ||||
PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) | ||||
PRKCA | Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (575 aa) | ||||
PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) | ||||
CCDC170 | Coiled-coil domain containing 170. (653 aa) | ||||
ENSPCOP00000029403 | Protein kinase domain-containing protein. (429 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) | ||||
PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa) | ||||
WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) | ||||
PLCE1 | Phosphoinositide phospholipase C. (2299 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (789 aa) | ||||
ERBB2 | Receptor protein-tyrosine kinase. (1252 aa) | ||||
TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (840 aa) | ||||
TIAM1 | T cell lymphoma invasion and metastasis 1. (1590 aa) | ||||
IQANK1 | IQ motif and ankyrin repeat containing 1. (564 aa) | ||||
ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1337 aa) | ||||
PPP1CA | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa) | ||||
PPP1R12C | Protein phosphatase 1 regulatory subunit. (771 aa) | ||||
PLAU | Plasminogen activator, urokinase. (432 aa) | ||||
ITGA2 | Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1129 aa) | ||||
CD44 | CD44 molecule (Indian blood group). (746 aa) | ||||
CAV2 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa) | ||||
ZNF774 | Zinc finger protein 774. (482 aa) | ||||
WNT8A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa) | ||||
SDC2 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa) | ||||
FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (278 aa) | ||||
NUDT16L1 | Nudix hydrolase 16 like 1. (226 aa) | ||||
PTK2 | Protein tyrosine kinase 2. (1089 aa) | ||||
ENSPCOP00000025645 | Uncharacterized protein. (162 aa) | ||||
WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) | ||||
ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2732 aa) | ||||
CAMK2A | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (471 aa) | ||||
CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa) | ||||
PLAUR | Plasminogen activator, urokinase receptor. (333 aa) | ||||
FN1 | Fibronectin 1. (2290 aa) | ||||
THBS1 | Thrombospondin 1. (1185 aa) | ||||
PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1304 aa) | ||||
BRAF | B-Raf proto-oncogene, serine/threonine kinase. (745 aa) | ||||
WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) | ||||
VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa) | ||||
SDC1 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (310 aa) | ||||
ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (599 aa) | ||||
DDX5 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) | ||||
ENSPCOP00000023046 | Uncharacterized protein. (150 aa) | ||||
HOXD10 | Homeobox D10. (340 aa) | ||||
HSPB2 | SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (182 aa) | ||||
MRAS | Muscle RAS oncogene homolog. (208 aa) | ||||
WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa) | ||||
PTCH1 | Patched 1. (1449 aa) | ||||
CAMK2G | Calcium/calmodulin dependent protein kinase II gamma. (600 aa) | ||||
CDC42 | Uncharacterized protein. (191 aa) | ||||
SDC4 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (200 aa) | ||||
ACTG1 | Actin gamma 1. (404 aa) | ||||
MET | MET proto-oncogene, receptor tyrosine kinase. (1397 aa) | ||||
IGF1R | Tyrosine-protein kinase receptor. (1350 aa) | ||||
PPP1CC | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa) | ||||
CAMK2D | Calcium/calmodulin dependent protein kinase II delta. (503 aa) | ||||
WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) | ||||
COL1A1 | Collagen type I alpha 1 chain. (1461 aa) | ||||
HPSE2 | Heparanase 2 (inactive). (592 aa) | ||||
HRAS | HRas proto-oncogene, GTPase. (189 aa) | ||||
VAV3 | Vav guanine nucleotide exchange factor 3. (765 aa) | ||||
C11orf1 | Chromosome 11 open reading frame 1. (180 aa) | ||||
IGF1 | Insulin like growth factor 1. (208 aa) | ||||
FRS2 | Fibroblast growth factor receptor substrate 2. (508 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
FZD2 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (547 aa) | ||||
ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2664 aa) | ||||
SRC | Tyrosine-protein kinase. (543 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) | ||||
PDCD4 | Programmed cell death 4. (450 aa) | ||||
PIK3R2 | Uncharacterized protein. (726 aa) | ||||
EGFR | Receptor protein-tyrosine kinase. (1210 aa) | ||||
HGF | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (703 aa) | ||||
ENSPCOP00000018033 | HH_signal domain-containing protein. (110 aa) | ||||
CD63 | Tetraspanin. (237 aa) | ||||
GRB2 | Growth factor receptor bound protein 2. (217 aa) | ||||
CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) | ||||
ENSPCOP00000017736 | Uncharacterized protein. (177 aa) | ||||
CTSL | Cathepsin L; Belongs to the peptidase C1 family. (333 aa) | ||||
MAPK14 | Mitogen-activated protein kinase 14. (340 aa) | ||||
ANK2 | Ankyrin 2. (3925 aa) | ||||
PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) | ||||
MAP2K1 | Mitogen-activated protein kinase kinase 1. (377 aa) | ||||
ANK3 | Ankyrin 3. (4372 aa) | ||||
FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa) | ||||
PIK3CA | Phosphatidylinositol 3-kinase catalytic subunit type 3. (933 aa) | ||||
ENSPCOP00000015361 | Uncharacterized protein. (129 aa) | ||||
TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (235 aa) | ||||
TIMP3 | TIMP metallopeptidase inhibitor 3. (211 aa) | ||||
MAPK11 | Mitogen-activated protein kinase. (443 aa) | ||||
VAV1 | Vav guanine nucleotide exchange factor 1. (806 aa) | ||||
PPP1R12A | Protein phosphatase 1 regulatory subunit. (1000 aa) | ||||
FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) | ||||
MAPK12 | Mitogen-activated protein kinase. (367 aa) | ||||
ENSPCOP00000013858 | Uncharacterized protein. (78 aa) | ||||
RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (487 aa) | ||||
GAB1 | GRB2 associated binding protein 1. (683 aa) | ||||
LOC105812777 | Uncharacterized protein. (436 aa) | ||||
PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (607 aa) | ||||
RRAS | RAS related. (220 aa) | ||||
PXN | Paxillin. (1073 aa) | ||||
IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (326 aa) | ||||
CSDE1 | Cold shock domain containing E1. (798 aa) | ||||
DCN | Decorin; May affect the rate of fibrils formation. (290 aa) | ||||
MMP9 | Matrix metallopeptidase 9. (709 aa) | ||||
FLNC | Filamin C. (2725 aa) | ||||
PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1233 aa) | ||||
ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1361 aa) | ||||
CBL | Cbl proto-oncogene. (891 aa) | ||||
VTN | SMB domain-containing protein. (465 aa) | ||||
PPP1CB | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (282 aa) | ||||
ARAF | A-Raf proto-oncogene, serine/threonine kinase. (609 aa) | ||||
ANKRD60 | Ankyrin repeat domain 60. (339 aa) | ||||
RHOC | Ras homolog family member C. (193 aa) | ||||
WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) | ||||
RRAS2 | RAS related 2. (201 aa) | ||||
ITGAV | Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1047 aa) | ||||
ARHGEF1 | Rho guanine nucleotide exchange factor 1. (967 aa) | ||||
ACTL8 | Actin like 8; Belongs to the actin family. (351 aa) | ||||
FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) | ||||
SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (882 aa) | ||||
ANK1 | Ankyrin 1. (1859 aa) | ||||
KRAS | Uncharacterized protein. (75 aa) | ||||
ENSPCOP00000009588 | Uncharacterized protein. (316 aa) | ||||
LOC105825340 | RRM domain-containing protein. (501 aa) | ||||
LOC105819868 | Protein kinase domain-containing protein. (302 aa) | ||||
SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa) | ||||
FZD8 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (406 aa) | ||||
WNT9A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) | ||||
WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) | ||||
MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) | ||||
PIK3R3 | Uncharacterized protein. (454 aa) | ||||
WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) | ||||
MMP2 | Matrix metallopeptidase 2. (552 aa) | ||||
ZSCAN2 | Zinc finger and SCAN domain containing 2. (615 aa) | ||||
VAV2 | Vav guanine nucleotide exchange factor 2. (771 aa) | ||||
ROCK1 | Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1316 aa) | ||||
WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) | ||||
ENSPCOP00000007779 | Uncharacterized protein. (301 aa) | ||||
PAK1 | Non-specific serine/threonine protein kinase. (544 aa) | ||||
LOC105812775 | SWIB domain-containing protein. (243 aa) | ||||
CAMK2B | Calcium/calmodulin dependent protein kinase II beta. (665 aa) | ||||
HSPG2 | Heparan sulfate proteoglycan 2. (4370 aa) | ||||
RHOA | Ras homolog family member A. (193 aa) | ||||
PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (399 aa) | ||||
HBEGF | Heparin binding EGF like growth factor. (208 aa) | ||||
WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) | ||||
ITGA5 | Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1041 aa) | ||||
NRAS | NRAS proto-oncogene, GTPase. (189 aa) | ||||
FZD7 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa) | ||||
RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) | ||||
KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) | ||||
PDPK1 | 3-phosphoinositide dependent protein kinase 1. (558 aa) | ||||
GPC1 | Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (558 aa) | ||||
ACTB | Actin beta. (378 aa) | ||||
HIF1A | Hypoxia inducible factor 1 subunit alpha. (826 aa) | ||||
CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa) | ||||
ITGB5 | Integrin beta; Belongs to the integrin beta chain family. (802 aa) | ||||
ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2702 aa) | ||||
FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa) | ||||
FLNA | Filamin A. (2647 aa) | ||||
MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (453 aa) | ||||
CTTN | Cortactin. (550 aa) | ||||
FZD9 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa) | ||||
ENSPCOP00000002927 | Uncharacterized protein. (160 aa) | ||||
ITGB1 | Integrin beta. (585 aa) | ||||
ENSPCOP00000002686 | CSD_1 domain-containing protein. (293 aa) | ||||
COL1A2 | Collagen type I alpha 2 chain. (1364 aa) | ||||
WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (190 aa) | ||||
GPC3 | Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa) | ||||
IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa) | ||||
FGFR1 | Fibroblast growth factor receptor. (846 aa) | ||||
EIF4B | Eukaryotic translation initiation factor 4B. (616 aa) | ||||
ARSI | Arylsulfatase family member I. (572 aa) | ||||
LOC105822640 | Integrin beta; Belongs to the integrin beta chain family. (454 aa) | ||||
IQGAP1 | IQ motif containing GTPase activating protein 1. (1400 aa) | ||||
PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) | ||||
MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2536 aa) | ||||
WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) | ||||
MAP2K2 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa) | ||||
TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) | ||||
FAS | Fas cell surface death receptor. (309 aa) | ||||
TWIST2 | Twist family bHLH transcription factor 2. (160 aa) | ||||
LOC105827009 | 40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (246 aa) | ||||
EZR | Ezrin. (586 aa) | ||||
WNT7B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) | ||||
ELK1 | ETS transcription factor ELK1. (430 aa) | ||||
ARHGEF12 | Rho guanine nucleotide exchange factor 12. (1496 aa) | ||||
SMAD2 | Mothers against decapentaplegic homolog. (462 aa) | ||||
PPP1R12B | Protein phosphatase 1 regulatory subunit. (1042 aa) | ||||
MSN | Moesin. (577 aa) | ||||
WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa) | ||||
TFAP4 | Transcription factor AP-4. (338 aa) |