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| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (381 aa) |
| | WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | NCOA7 | Nuclear receptor coactivator 7. (886 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa) |
| | SHC1 | SHC adaptor protein 1. (582 aa) |
| | WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (332 aa) |
| | TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (320 aa) |
| | FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) |
| | TCF7 | Transcription factor 7. (303 aa) |
| | FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (502 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (394 aa) |
| | HEY2 | Hes related family bHLH transcription factor with YRPW motif 2. (337 aa) |
| | WNT2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | AXIN1 | Axin 1. (865 aa) |
| | CEP152 | Centrosomal protein 152. (1655 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | TCF7L1 | Transcription factor 7 like 1. (590 aa) |
| | POLK | DNA polymerase kappa. (832 aa) |
| | WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | CCDC170 | Coiled-coil domain containing 170. (653 aa) |
| | FGF21 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) |
| | NOTCH4 | Notch receptor 4. (2000 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | ENSPCOP00000028883 | Protein kinase domain-containing protein. (138 aa) |
| | APC | APC regulator of WNT signaling pathway. (2844 aa) |
| | WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1606 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1252 aa) |
| | PGR | Nuclear receptor domain-containing protein. (592 aa) |
| | FGF3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (233 aa) |
| | SP1 | Sp1 transcription factor. (788 aa) |
| | DVL1 | Dishevelled segment polarity protein 1. (722 aa) |
| | WNT8A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa) |
| | CDK6 | Cyclin dependent kinase 6. (263 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | HES4 | Hes family bHLH transcription factor 4. (239 aa) |
| | ENSPCOP00000024796 | Uncharacterized protein. (442 aa) |
| | NFKB2 | Nuclear factor kappa B subunit 2. (895 aa) |
| | FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (745 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa) |
| | ENSPCOP00000023392 | Uncharacterized protein. (157 aa) |
| | ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (599 aa) |
| | APC2 | APC regulator of WNT signaling pathway 2. (2300 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (390 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa) |
| | GADD45A | Growth arrest and DNA damage inducible alpha. (165 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1350 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | DDB2 | Damage specific DNA binding protein 2. (426 aa) |
| | GADD45G | Growth arrest and DNA damage inducible gamma. (161 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (199 aa) |
| | SHC3 | SHC adaptor protein 3. (596 aa) |
| | IGF1 | Insulin like growth factor 1. (208 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | FZD2 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (547 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | PIK3R2 | Uncharacterized protein. (726 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1210 aa) |
| | E2F1 | E2F transcription factor 1. (436 aa) |
| | NCOA3 | Nuclear receptor coactivator. (1410 aa) |
| | LOC105822621 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | NCOA1 | Nuclear receptor coactivator 1. (1270 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa) |
| | DVL3 | Dishevelled segment polarity protein 3. (716 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1. (377 aa) |
| | FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa) |
| | PIK3CA | Phosphatidylinositol 3-kinase catalytic subunit type 3. (933 aa) |
| | DLL3 | Delta like canonical Notch ligand 3. (585 aa) |
| | EGF | Epidermal growth factor. (1132 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) |
| | RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (487 aa) |
| | SHC2 | Uncharacterized protein. (578 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa) |
| | CSDE1 | Cold shock domain containing E1. (798 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (619 aa) |
| | ENSPCOP00000012342 | RING-type domain-containing protein. (80 aa) |
| | ENSPCOP00000011475 | Protein kinase domain-containing protein. (89 aa) |
| | ARAF | A-Raf proto-oncogene, serine/threonine kinase. (609 aa) |
| | RB1 | RB transcriptional corepressor 1. (787 aa) |
| | WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | GPSM3 | G protein signaling modulator 3. (160 aa) |
| | LOC105823019 | Uncharacterized protein. (87 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | GALK2 | Galactokinase 2. (458 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (882 aa) |
| | FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1341 aa) |
| | KRAS | Uncharacterized protein. (75 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa) |
| | FZD8 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (406 aa) |
| | HES5 | Orange domain-containing protein. (94 aa) |
| | E2F3 | E2F transcription factor 3. (464 aa) |
| | WNT9A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | FGF22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (172 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | BRCA2 | BRCA2 DNA repair associated. (3419 aa) |
| | PIK3R3 | Uncharacterized protein. (454 aa) |
| | LRP6 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1579 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | SHC4 | SHC adaptor protein 4. (630 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | AXIN2 | Axin 2. (716 aa) |
| | HES1 | Hes family bHLH transcription factor 1. (280 aa) |
| | LOC105822779 | Uncharacterized protein. (325 aa) |
| | DVL2 | Dishevelled segment polarity protein 2. (736 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | FZD7 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | GADD45B | Growth arrest and DNA damage inducible beta. (160 aa) |
| | JAG1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa) |
| | NOTCH3 | Notch receptor 3. (2318 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa) |
| | LOC105805030 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (150 aa) |
| | NOTCH1 | Notch receptor 1. (2420 aa) |
| | DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (432 aa) |
| | ENSPCOP00000004497 | Uncharacterized protein. (280 aa) |
| | JAG2 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1101 aa) |
| | ESR2 | Estrogen receptor 2. (471 aa) |
| | DLL4 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa) |
| | FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (453 aa) |
| | FZD9 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa) |
| | NOTCH2 | Notch receptor 2. (2471 aa) |
| | HEY1 | Hes related family bHLH transcription factor with YRPW motif 1. (308 aa) |
| | ENSPCOP00000002686 | CSD_1 domain-containing protein. (293 aa) |
| | WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (190 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (846 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2536 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | MAP2K2 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | WNT7B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | E2F2 | E2F transcription factor 2. (435 aa) |
| | HEYL | Hes related family bHLH transcription factor with YRPW motif like. (328 aa) |
| | WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa) |
