STRINGSTRING
ITGB5 ITGB5 LEF1 LEF1 ACTB ACTB ITGA1 ITGA1 CACNA2D1 CACNA2D1 ITGB7 ITGB7 ITGA5 ITGA5 CDH2 CDH2 CACNA2D4 CACNA2D4 CACNG8 CACNG8 PKP2 PKP2 ITGB6 ITGB6 ATP2A1 ATP2A1 LAMA1 LAMA1 ITGB1 ITGB1 CACNG5 CACNG5 LOC105822640 LOC105822640 ITGA4 ITGA4 CACNA2D3 CACNA2D3 TCF7 TCF7 CACNA2D2 CACNA2D2 LMNA LMNA ENSPCOP00000030822 ENSPCOP00000030822 CTNNA1 CTNNA1 ENSPCOP00000030414 ENSPCOP00000030414 ITGA9 ITGA9 TCF7L1 TCF7L1 CACNB3 CACNB3 GJA1 GJA1 ACTN2 ACTN2 ITGA2B ITGA2B ENSPCOP00000027120 ENSPCOP00000027120 ITGA2 ITGA2 DSC3 DSC3 DSC1 DSC1 ITGB4 ITGB4 ITGA7 ITGA7 CACNA1F CACNA1F SGCG SGCG ENSPCOP00000024369 ENSPCOP00000024369 CACNB4 CACNB4 ITGA3 ITGA3 DAG1 DAG1 SLC8A2 SLC8A2 CTNNB1 CTNNB1 DSG2 DSG2 PLEC PLEC ACTG1 ACTG1 CTNNA3 CTNNA3 ITGA10 ITGA10 LAMA2 LAMA2 CACNA1S CACNA1S ITGA8 ITGA8 LRRC66 LRRC66 ENSPCOP00000020279 ENSPCOP00000020279 CACNG4 CACNG4 CACNB2 CACNB2 ITGA6 ITGA6 CACNA1C CACNA1C ITGB8 ITGB8 CACNG3 CACNG3 CACNG1 CACNG1 SLC39A12 SLC39A12 ATP2A2 ATP2A2 DSC2 DSC2 SLC8A3 SLC8A3 ENSPCOP00000014148 ENSPCOP00000014148 CTNNA2 CTNNA2 CACNG7 CACNG7 SGCA SGCA CACNG2 CACNG2 CACNA1D CACNA1D ATP2A3 ATP2A3 SLC8A1 SLC8A1 ITGA11 ITGA11 TCF7L2 TCF7L2 JUP JUP CACNB1 CACNB1 SGCD SGCD ACTN3 ACTN3 ITGAV ITGAV RYR2 RYR2 DES DES ACTL8 ACTL8 DSG3 DSG3 EMD EMD CACNG6 CACNG6 DSP DSP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITGB5Integrin beta; Belongs to the integrin beta chain family. (802 aa)
LEF1Lymphoid enhancer binding factor 1. (432 aa)
ACTBActin beta. (378 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1025 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (740 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (797 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1041 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
CACNA2D4Calcium voltage-gated channel auxiliary subunit alpha2delta 4. (1136 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (419 aa)
PKP2Plakophilin 2. (838 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (766 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1028 aa)
LAMA1Laminin subunit alpha 1. (2945 aa)
ITGB1Integrin beta. (585 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (275 aa)
LOC105822640Integrin beta; Belongs to the integrin beta chain family. (454 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (964 aa)
CACNA2D3Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (1091 aa)
TCF7Transcription factor 7. (303 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1153 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (665 aa)
ENSPCOP00000030822Uncharacterized protein. (911 aa)
CTNNA1Catenin alpha 1. (906 aa)
ENSPCOP00000030414Uncharacterized protein. (347 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1035 aa)
TCF7L1Transcription factor 7 like 1. (590 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (484 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
ACTN2Actinin alpha 2. (874 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1039 aa)
ENSPCOP00000027120Uncharacterized protein. (1243 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1129 aa)
DSC3Desmocollin 3; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (698 aa)
DSC1Desmocollin 1. (722 aa)
ITGB4Integrin beta. (1806 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1181 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1973 aa)
SGCGSarcoglycan gamma. (291 aa)
ENSPCOP00000024369Uncharacterized protein; Belongs to the intermediate filament family. (156 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (520 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1066 aa)
DAG1Dystroglycan 1. (895 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (926 aa)
CTNNB1Catenin beta 1. (781 aa)
DSG2Desmoglein 2. (1029 aa)
PLECPlectin. (4689 aa)
ACTG1Actin gamma 1. (404 aa)
CTNNA3Catenin alpha 3. (783 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1162 aa)
LAMA2Laminin subunit alpha 2. (2944 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1544 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1035 aa)
LRRC66Leucine rich repeat containing 66. (781 aa)
ENSPCOP00000020279Calponin-homology (CH) domain-containing protein. (425 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2016 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (768 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (222 aa)
SLC39A12Solute carrier family 39 member 12. (599 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
DSC2Desmocollin 2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (901 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
ENSPCOP00000014148Uncharacterized protein. (733 aa)
CTNNA2Catenin alpha 2. (822 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
SGCASarcoglycan alpha. (387 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2180 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1033 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (974 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1089 aa)
TCF7L2Transcription factor 7 like 2. (619 aa)
JUPJunction plakoglobin. (745 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (676 aa)
SGCDSarcoglycan delta. (290 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (936 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1047 aa)
RYR2Ryanodine receptor 2. (4825 aa)
DESDesmin; Belongs to the intermediate filament family. (470 aa)
ACTL8Actin like 8; Belongs to the actin family. (351 aa)
DSG3Desmoglein 3; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1001 aa)
EMDEmerin. (260 aa)
CACNG6Calcium voltage-gated channel auxiliary subunit gamma 6. (184 aa)
DSPDesmoplakin. (2868 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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