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nrdA nrdA nrdB nrdB XALC_0163 XALC_0163 XALC_0164 XALC_0164 dut dut tmk tmk adk adk gmk gmk spoT spoT dcd dcd pyrG pyrG ndk ndk XALC_2767 XALC_2767 thyA thyA lgt lgt tdk tdk
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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nrdAProbable ribonucleoside-diphosphate reductase alpha subunit protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (803 aa)
nrdBProbable ribonucleotide-diphosphate reductase beta subunit protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (346 aa)
XALC_0163Putative flavodoxin protein. (174 aa)
XALC_0164Putative thioredoxin protein. (110 aa)
dutProbable deoxyuridine 5'-triphosphate nucleotidohydrolase (dutp pyrophosphatase) protein; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (156 aa)
tmkProbable thymidylate kinase (dtmp kinase) protein; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (223 aa)
adkProbable adenylate kinase protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (187 aa)
gmkProbable guanylate kinase (gmp kinase) protein; Essential for recycling GMP and indirectly, cGMP. (208 aa)
spoTProbable guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (723 aa)
dcdProbable deoxycytidine triphosphate deaminase (dctp deaminase) protein; Catalyzes the deamination of dCTP to dUTP. (188 aa)
pyrGProbable ctp synthase (utp--ammonia ligase) protein; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (554 aa)
ndkProbable nucleoside diphosphate kinase (ndk) (ndp kinase)(nucleoside-2-p kinase) protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (141 aa)
XALC_2767Probable dihydrofolate reductase protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (169 aa)
thyAProbable thymidylate synthase protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa)
lgtProbable prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (292 aa)
tdkProbable thymidine kinase protein. (208 aa)
Your Current Organism:
Xanthomonas albilineans
NCBI taxonomy Id: 380358
Other names: X. albilineans GPE PC73, Xanthomonas albilineans GPE PC73, Xanthomonas albilineans str. GPE PC73, Xanthomonas albilineans strain GPE PC73
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