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AHA_2947 AHA_2947 nuoC nuoC AHA_1779 AHA_1779 AHA_1777 AHA_1777 nuoH nuoH nuoI nuoI nuoK nuoK AHA_1772 AHA_1772 AHA_1771 AHA_1771 nuoN nuoN gltA gltA AHA_1642 AHA_1642 cydB-1 cydB-1 AHA_1640 AHA_1640 ubiE ubiE AHA_0541 AHA_0541 ppc ppc AHA_0620 AHA_0620 mdh mdh AHA_0838 AHA_0838 aspA aspA nqrB nqrB nqrE-1 nqrE-1 icd icd AHA_1444 AHA_1444 AHA_1587 AHA_1587 napB napB sdhC sdhC AHA_1924 AHA_1924 sdhA sdhA AHA_1926 AHA_1926 sucA sucA sucC sucC sucD sucD AHA_1975 AHA_1975 AHA_2245 AHA_2245 AHA_2266 AHA_2266 ccoN ccoN ccoP ccoP AHA_2396 AHA_2396 glpC glpC AHA_2466 AHA_2466 AHA_2500 AHA_2500 HycD HycD HycE HycE AHA_2503 AHA_2503 hybC hybC AHA_2524 AHA_2524 AHA_2525 AHA_2525 AHA_2526 AHA_2526 AHA_2559 AHA_2559 AHA_2761 AHA_2761 aceB aceB cyoC cyoC AHA_2945 AHA_2945 aceK aceK AHA_3044 AHA_3044 AHA_3061 AHA_3061 AHA_3062 AHA_3062 AHA_3063 AHA_3063 frdA frdA AHA_3209 AHA_3209 AHA_3210 AHA_3210 nqrE-2 nqrE-2 AHA_3285 AHA_3285 AHA_3286 AHA_3286 AHA_3287 AHA_3287 fumC fumC AHA_3644 AHA_3644 cydB-2 cydB-2 cydA cydA AHA_3726 AHA_3726 acnB acnB petB petB AHA_4049 AHA_4049
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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AHA_2947Twin-arginine translocation pathway signal; Identified by match to protein family HMM TIGR01409. (641 aa)
nuoCNADH-quinone oxidoreductase chain c/d; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. (601 aa)
AHA_1779NADH-quinone oxidoreductase chain e; Identified by match to protein family HMM PF01257; match to protein family HMM TIGR01958. (180 aa)
AHA_1777NADH-quinone oxidoreductase, chain g; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (909 aa)
nuoHNADH-quinone oxidoreductase chain h; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (322 aa)
nuoINADH-quinone oxidoreductase chain i; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (180 aa)
nuoKNADH-quinone oxidoreductase chain k; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (102 aa)
AHA_1772NADH-quinone oxidoreductase chain l; Identified by match to protein family HMM PF00361; match to protein family HMM PF00662; match to protein family HMM TIGR01974. (615 aa)
AHA_1771NADH-quinone oxidoreductase chain m; Identified by match to protein family HMM PF00361; match to protein family HMM TIGR01972. (506 aa)
nuoNNADH-quinone oxidoreductase chain n; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (487 aa)
gltACitrate synthase I; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family. (428 aa)
AHA_1642Cyd operon protein YbgT; Identified by match to protein family HMM TIGR02106. (37 aa)
cydB-1Cytochrome D ubiquinol oxidase, subunit II; Identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203. (375 aa)
AHA_1640Cytochrome D ubiquinol oxidase subunit I; Identified by match to protein family HMM PF01654. (523 aa)
ubiEUbiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (250 aa)
AHA_0541Identified by match to protein family HMM PF01292. (184 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (877 aa)
AHA_0620Conserved hypothetical protein. (508 aa)
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. (311 aa)
AHA_0838Identified by match to protein family HMM PF01292. (184 aa)
aspAAspartate ammonia-lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00839. (480 aa)
nqrBNADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. (409 aa)
nqrE-1NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family. (198 aa)
icdIsocitrate dehydrogenase, NADP-dependent; Identified by match to protein family HMM PF00180; match to protein family HMM TIGR00183. (417 aa)
AHA_1444Oligoketide cyclase/lipid transport protein; Identified by match to protein family HMM PF03364. (144 aa)
AHA_1587MauM/NapG ferredoxin-type protein; Identified by match to protein family HMM PF00037; match to protein family HMM TIGR00397. (244 aa)
napBperiplasmiC nitrate reductase, diheme cytochrome c subunit; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family. (151 aa)
sdhCSuccinate dehydrogenase, cytochrome b556 subunit; Identified by match to protein family HMM PF01127; match to protein family HMM TIGR02970. (129 aa)
AHA_1924Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (114 aa)
sdhASuccinate dehydrogenase, flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF02910; match to protein family HMM TIGR01812; match to protein family HMM TIGR01816; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa)
AHA_1926Succinate dehydrogenase iron-sulfur protein; Identified by match to protein family HMM TIGR00384; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (238 aa)
sucA2-oxoglutarate dehydrogenase, E1 component; Identified by match to protein family HMM PF00676; match to protein family HMM PF02779; match to protein family HMM TIGR00239. (958 aa)
sucCsuccinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
sucDsuccinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
AHA_1975Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (547 aa)
AHA_2245Conserved hypothetical protein. (221 aa)
AHA_22662-methylcitrate synthase; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family. (375 aa)
ccoNCytochrome c oxidase, Cbb3-type, subunit I; Identified by match to protein family HMM PF00115; match to protein family HMM TIGR00780; Belongs to the heme-copper respiratory oxidase family. (496 aa)
ccoPCytochrome c oxidase, cbb3-type, subunit III; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. (329 aa)
AHA_2396Conserved hypothetical protein. (239 aa)
glpCAnaerobic glycerol-3-phosphate dehydrogenase subunit C; Identified by match to protein family HMM PF00037; match to protein family HMM PF02754. (400 aa)
AHA_24664Fe-4S binding domain protein; Identified by match to protein family HMM PF00037; match to protein family HMM TIGR01409. (230 aa)
AHA_2500Hydrogenase-4 component B; Identified by match to protein family HMM PF00361. (623 aa)
HycDHydrogenase-4 component C; Identified by match to protein family HMM PF00146. (317 aa)
HycEHydrogenase-4 component G; Identified by match to protein family HMM PF00329; match to protein family HMM PF00346. (572 aa)
AHA_2503Hydrogenase-4 component H; Identified by match to protein family HMM PF00037. (185 aa)
hybCHydrogenase-2 large chain; Identified by similarity to SP:P37181; match to protein family HMM PF00374; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (567 aa)
AHA_2524Probable Ni/Fe-hydrogenase 2 b-type cytochrome subunit; Identified by match to protein family HMM PF03916. (395 aa)
AHA_2525Hydrogenase-2 operon protein HybA; Identified by match to protein family HMM PF00037; match to protein family HMM TIGR01409. (341 aa)
AHA_2526Hydrogenase (NiFe) small subunit (hydA); Identified by similarity to SP:P18637; match to protein family HMM PF01058; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409. (377 aa)
AHA_2559Fe-S oxidoreductase; Identified by match to protein family HMM PF02754. (263 aa)
AHA_27614Fe-4S binding domain protein; Identified by match to protein family HMM PF00037; match to protein family HMM TIGR01409. (222 aa)
aceBMalate synthase A; Identified by match to protein family HMM PF01274; match to protein family HMM TIGR01344. (535 aa)
cyoCCytochrome o ubiquinol oxidase, subunit III; Identified by match to protein family HMM PF00510; match to protein family HMM TIGR02842. (203 aa)
AHA_2945Cytochrome o subunit 1; Oxidase BO(3) subunit 1; identified by match to protein family HMM PF00115; match to protein family HMM TIGR02843; Belongs to the heme-copper respiratory oxidase family. (658 aa)
aceKIsocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (575 aa)
AHA_3044Cytochrome b561; Identified by match to protein family HMM PF01292. (181 aa)
AHA_3061Formate dehydrogenase, cytochrome b556 subunit; Identified by match to protein family HMM TIGR01583. (323 aa)
AHA_3062Formate dehydrogenase iron-sulfur subunit; Identified by match to protein family HMM PF00037. (207 aa)
AHA_3063Formate dehydrogenase; Identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (966 aa)
frdAFumarate reductase, flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF02910; match to protein family HMM PF07992; match to protein family HMM TIGR01176; match to protein family HMM TIGR01812. (594 aa)
AHA_3209Fumarate reductase iron-sulfur protein; Identified by match to protein family HMM PF00037; match to protein family HMM TIGR00384; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (244 aa)
AHA_3210Fumarate reductase subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane; Belongs to the FrdC family. (132 aa)
nqrE-2NADH:ubiquinone oxidoreductase, na(+)-translocating, e subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family. (199 aa)
AHA_3285TtrA; Identified by match to protein family HMM PF01568; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1035 aa)
AHA_3286Tetrathionate reductase subunit C; Identified by match to protein family HMM PF03916. (368 aa)
AHA_3287Tetrathionate reductase, subunit B; Identified by match to protein family HMM PF00037. (262 aa)
fumCFumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
AHA_3644Cyd operon protein YbgT; Identified by match to protein family HMM PF08173; match to protein family HMM TIGR02106. (38 aa)
cydB-2Cytochrome d ubiquinol oxidase, subunit II; Identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203. (378 aa)
cydACytochrome d ubiquinol oxidase, subunit I; Identified by match to protein family HMM PF01654. (518 aa)
AHA_3726Periplasmic protein. (224 aa)
acnBAconitate hydratase 2; Identified by match to protein family HMM PF00330; match to protein family HMM PF06434; match to protein family HMM TIGR00117; Belongs to the aconitase/IPM isomerase family. (878 aa)
petBUbiquinol-cytochrome c reductase, cytochrome b subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (405 aa)
AHA_4049Molybdopterin guanine dinucleotide-containing S/N-oxide reductase family protein; Identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; match to protein family HMM TIGR01409. (826 aa)
Your Current Organism:
Aeromonas hydrophila
NCBI taxonomy Id: 380703
Other names: A. hydrophila subsp. hydrophila ATCC 7966, Aeromonas hydrophila subsp. hydrophila ATCC 7966, Aeromonas hydrophila subsp. hydrophila str. ATCC 7966, Aeromonas hydrophila subsp. hydrophila strain ATCC 7966
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