STRINGSTRING
AHA_2091 AHA_2091 acpP acpP cobB cobB accD accD AHA_2865 AHA_2865 dnaK dnaK gap-1 gap-1 acpP-2 acpP-2 ahyR ahyR AHA_1389 AHA_1389 cheA-2 cheA-2 cheY cheY AHA_1182 AHA_1182 AHA_0890 AHA_0890 nifJ-1 nifJ-1 fur fur gloB gloB AHA_1667 AHA_1667 tig tig eno eno luxS luxS AHA_0917 AHA_0917 AHA_0556 AHA_0556
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AHA_2091Beta-glucosidase; Identified by match to protein family HMM PF00232; Belongs to the glycosyl hydrolase 1 family. (477 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (78 aa)
cobBPutative nicotinic acid mononucleotide:5, 6-dimethylbenzimidazole(DMB)phosphoribosyltransferase; Identified by match to protein family HMM PF02146; Belongs to the sirtuin family. Class III subfamily. (257 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (287 aa)
AHA_2865Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817. (366 aa)
dnaKChaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (642 aa)
gap-1Glyceraldehyde-3-phosphate dehydrogenase, type I; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (457 aa)
acpP-2Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (82 aa)
ahyRTranscriptional activator protein AhyR; Identified by similarity to SP:P0A3J6; match to protein family HMM PF00196; match to protein family HMM PF03472; match to protein family HMM PF04967. (261 aa)
AHA_1389Identified by match to protein family HMM PF01656. (264 aa)
cheA-2Chemotaxis protein CheA; Identified by similarity to GB:AAC08064.1; match to protein family HMM PF01584; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM PF02895. (728 aa)
cheYChemotaxis protein CheY; Identified by similarity to SP:Q51455; match to protein family HMM PF00072. (127 aa)
AHA_1182Outer membrane protein; Identified by match to protein family HMM PF03938; Belongs to the skp family. (170 aa)
AHA_0890Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (717 aa)
nifJ-1Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176. (1191 aa)
furFerric uptake regulation protein; Identified by similarity to SP:P0A9A9; match to protein family HMM PF01475; Belongs to the Fur family. (142 aa)
gloBProbable hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (254 aa)
AHA_1667Maltose-binding periplasmic protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family. (393 aa)
tigTrigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (436 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (433 aa)
luxSS-Ribosylhomocysteinase (LuxS); Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (169 aa)
AHA_0917Polyphosphate glucokinase; Identified by match to protein family HMM PF00480. (252 aa)
AHA_0556Autoinducer synthesis protein AhyI; Identified by match to protein family HMM PF00765. (207 aa)
Your Current Organism:
Aeromonas hydrophila
NCBI taxonomy Id: 380703
Other names: A. hydrophila subsp. hydrophila ATCC 7966, Aeromonas hydrophila subsp. hydrophila ATCC 7966, Aeromonas hydrophila subsp. hydrophila str. ATCC 7966, Aeromonas hydrophila subsp. hydrophila strain ATCC 7966
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