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SLX1 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (424 aa) | ||||
G3XMF0_ASPNA | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1165 aa) | ||||
G3XMU0_ASPNA | BTP domain-containing protein. (905 aa) | ||||
G3XMY2_ASPNA | DNA helicase; Belongs to the MCM family. (851 aa) | ||||
G3XN54_ASPNA | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2461 aa) | ||||
G3XN56_ASPNA | Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (271 aa) | ||||
G3XN97_ASPNA | Uncharacterized protein. (1108 aa) | ||||
G3XNF5_ASPNA | Uncharacterized protein. (764 aa) | ||||
G3XNZ7_ASPNA | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (650 aa) | ||||
ASN41996 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2796 aa) | ||||
G3XPJ6_ASPNA | Uncharacterized protein. (557 aa) | ||||
G3XPL3_ASPNA | DNA helicase; Belongs to the MCM family. (922 aa) | ||||
G3XPT6_ASPNA | 3'-5' exonuclease domain-containing protein. (309 aa) | ||||
G3XPT9_ASPNA | Cell division control protein; Belongs to the CDC6/cdc18 family. (607 aa) | ||||
G3XPV4_ASPNA | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1107 aa) | ||||
G3XPW1_ASPNA | Protein kinase domain-containing protein. (245 aa) | ||||
G3XQW7_ASPNA | Uncharacterized protein. (399 aa) | ||||
G3XRC1_ASPNA | MCM domain-containing protein; Belongs to the MCM family. (2047 aa) | ||||
G3XRR9_ASPNA | Uncharacterized protein. (860 aa) | ||||
G3XRV4_ASPNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (922 aa) | ||||
G3XS52_ASPNA | DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (500 aa) | ||||
G3XS56_ASPNA | Uncharacterized protein. (555 aa) | ||||
G3XSC3_ASPNA | Uncharacterized protein. (858 aa) | ||||
G3XT02_ASPNA | Uncharacterized protein. (541 aa) | ||||
G3XT30_ASPNA | Sld5 domain-containing protein. (223 aa) | ||||
G3XT57_ASPNA | DNA repair protein RAD1. (466 aa) | ||||
G3XUM6_ASPNA | UmuC domain-containing protein. (604 aa) | ||||
G3XVJ1_ASPNA | DNA ligase. (915 aa) | ||||
G3XVJ4_ASPNA | DNA helicase; Belongs to the MCM family. (1028 aa) | ||||
G3XWW2_ASPNA | HORMA domain-containing protein. (277 aa) | ||||
G3XWW5_ASPNA | Uncharacterized protein. (396 aa) | ||||
G3XX42_ASPNA | DNA polymerase. (1105 aa) | ||||
G3XXD6_ASPNA | AAA domain-containing protein. (342 aa) | ||||
G3XXP7_ASPNA | Checkpoint protein; Belongs to the HUS1 family. (382 aa) | ||||
G3XXQ3_ASPNA | Uncharacterized protein. (117 aa) | ||||
G3XY97_ASPNA | DNA mismatch repair protein. (850 aa) | ||||
G3XZ45_ASPNA | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (629 aa) | ||||
G3XZQ1_ASPNA | WD_REPEATS_REGION domain-containing protein. (838 aa) | ||||
G3XZR3_ASPNA | EthD domain-containing protein. (153 aa) | ||||
G3XZV1_ASPNA | SAE2 domain-containing protein. (823 aa) | ||||
G3Y085_ASPNA | RECA_2 domain-containing protein. (490 aa) | ||||
G3Y0C8_ASPNA | AAA domain-containing protein. (926 aa) | ||||
G3Y0E7_ASPNA | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (825 aa) | ||||
G3Y0R2_ASPNA | ERCC4 domain-containing protein. (583 aa) | ||||
G3Y0U9_ASPNA | 5'-3' exonuclease. (543 aa) | ||||
G3Y142_ASPNA | Uncharacterized protein; Belongs to the cytochrome P450 family. (467 aa) | ||||
G3Y1A5_ASPNA | DNA helicase; Belongs to the MCM family. (720 aa) | ||||
G3Y1S0_ASPNA | Protein kinase domain-containing protein. (784 aa) | ||||
G3Y1W5_ASPNA | AAA domain-containing protein. (758 aa) | ||||
G3Y1Y6_ASPNA | DNA mismatch repair protein. (1043 aa) | ||||
G3Y201_ASPNA | Uncharacterized protein. (302 aa) | ||||
G3Y203_ASPNA | DNA polymerase. (1971 aa) | ||||
G3Y286_ASPNA | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (269 aa) | ||||
G3Y294_ASPNA | AAA domain-containing protein. (734 aa) | ||||
G3Y2T2_ASPNA | Replication factor C subunit 1. (1035 aa) | ||||
G3Y2T4_ASPNA | AAA domain-containing protein. (352 aa) | ||||
G3Y2W7_ASPNA | AA_TRNA_LIGASE_II domain-containing protein. (574 aa) | ||||
G3Y370_ASPNA | DNA_pol_E_B domain-containing protein. (748 aa) | ||||
G3Y383_ASPNA | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (592 aa) | ||||
G3Y3G1_ASPNA | Uncharacterized protein. (273 aa) | ||||
G3Y3H7_ASPNA | DNA ligase. (834 aa) | ||||
G3Y581_ASPNA | AAA domain-containing protein. (396 aa) | ||||
G3Y5C5_ASPNA | DUF1767 domain-containing protein. (237 aa) | ||||
G3Y5M5_ASPNA | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (514 aa) | ||||
G3Y5M9_ASPNA | 5'-3' exonuclease. (672 aa) | ||||
G3Y5R4_ASPNA | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2224 aa) | ||||
G3Y5U7_ASPNA | DNA_MISMATCH_REPAIR_2 domain-containing protein. (1653 aa) | ||||
G3Y5Z6_ASPNA | Zf-primase domain-containing protein. (775 aa) | ||||
G3Y618_ASPNA | NTF2 domain-containing protein. (122 aa) | ||||
MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (807 aa) | ||||
G3Y690_ASPNA | Uncharacterized protein. (312 aa) | ||||
G3Y6S1_ASPNA | DNA_MISMATCH_REPAIR_2 domain-containing protein. (956 aa) | ||||
G3Y6X1_ASPNA | ORC_WH_C domain-containing protein. (677 aa) | ||||
G3Y723_ASPNA | Uncharacterized protein. (429 aa) | ||||
G3Y7B8_ASPNA | Uncharacterized protein. (571 aa) | ||||
G3Y7Y0_ASPNA | Uncharacterized protein. (662 aa) | ||||
G3Y8P6_ASPNA | Uncharacterized protein. (609 aa) | ||||
G3Y8W0_ASPNA | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1188 aa) | ||||
G3Y910_ASPNA | Rif1_N domain-containing protein. (1594 aa) | ||||
G3Y991_ASPNA | Sld5 domain-containing protein. (178 aa) | ||||
G3Y992_ASPNA | Cnn_1N domain-containing protein. (896 aa) | ||||
G3Y9D4_ASPNA | UmuC domain-containing protein. (606 aa) | ||||
G3Y9H7_ASPNA | Uncharacterized protein. (361 aa) | ||||
G3YA04_ASPNA | DNA mismatch repair protein. (943 aa) | ||||
G3YA34_ASPNA | Uncharacterized protein. (576 aa) | ||||
G3YA53_ASPNA | Uncharacterized protein. (166 aa) | ||||
G3YA68_ASPNA | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (541 aa) | ||||
G3YAC9_ASPNA | Uncharacterized protein. (444 aa) | ||||
G3YAL0_ASPNA | Pectinesterase; Involved in maceration and soft-rotting of plant tissue. (327 aa) | ||||
G3YAT2_ASPNA | DBF4-type domain-containing protein. (674 aa) | ||||
G3YBG6_ASPNA | DNA polymerase. (1668 aa) | ||||
G3YBN8_ASPNA | Uncharacterized protein. (197 aa) | ||||
G3YBS8_ASPNA | Aspartic protease; Belongs to the peptidase A1 family. (620 aa) | ||||
FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (359 aa) | ||||
G3YBU4_ASPNA | Uncharacterized protein. (459 aa) | ||||
G3YBZ0_ASPNA | Uncharacterized protein. (417 aa) | ||||
G3YC28_ASPNA | Protein kinase domain-containing protein. (491 aa) | ||||
G3YC60_ASPNA | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (266 aa) | ||||
G3YCV4_ASPNA | RecQ family helicase MusN. (1452 aa) | ||||
G3YDU7_ASPNA | DNA_mis_repair domain-containing protein. (721 aa) | ||||
G3YDZ0_ASPNA | Uncharacterized protein. (375 aa) | ||||
G3YES0_ASPNA | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (792 aa) | ||||
G3YGA7_ASPNA | CBFD_NFYB_HMF domain-containing protein. (254 aa) | ||||
G3YGB4_ASPNA | SLD3 domain-containing protein. (908 aa) | ||||
G3YGG9_ASPNA | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (807 aa) | ||||
G3YGR5_ASPNA | DNA_MISMATCH_REPAIR_2 domain-containing protein. (485 aa) |