(38 nodes) DNA duplex unwinding network (Aspergillus niger)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3YHG6_ASPNA	Helicase ATP-binding domain-containing protein. (1071 aa)
	G3YFM4_ASPNA	Uncharacterized protein. (1457 aa)
	G3YEQ3_ASPNA	DNA repair helicase, subunit of TFIIH. (811 aa)
	G3YE60_ASPNA	Uncharacterized protein. (417 aa)
	G3YCV4_ASPNA	RecQ family helicase MusN. (1452 aa)
	G3YCP7_ASPNA	Uncharacterized protein. (514 aa)
	G3YC22_ASPNA	ATP-dependent DNA helicase-like protein. (987 aa)
	G3YA68_ASPNA	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (541 aa)
	G3Y9H7_ASPNA	Uncharacterized protein. (361 aa)
	G3Y9H0_ASPNA	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (458 aa)
	G3Y9D1_ASPNA	Uncharacterized protein. (531 aa)
	G3Y991_ASPNA	Sld5 domain-containing protein. (178 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (807 aa)
	G3Y4M2_ASPNA	Uncharacterized protein. (1697 aa)
	G3Y4J0_ASPNA	Uncharacterized protein. (1643 aa)
	G3Y445_ASPNA	DNA helicase. (721 aa)
	G3Y383_ASPNA	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (592 aa)
	G3Y319_ASPNA	Uncharacterized protein. (632 aa)
	G3Y210_ASPNA	Uncharacterized protein. (1123 aa)
	G3Y1A5_ASPNA	DNA helicase; Belongs to the MCM family. (720 aa)
	G3XZR3_ASPNA	EthD domain-containing protein. (153 aa)
	G3XYX7_ASPNA	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. (724 aa)
	G3XSL2_ASPNA	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (469 aa)
	G3XSC3_ASPNA	Uncharacterized protein. (858 aa)
	G3XS56_ASPNA	Uncharacterized protein. (555 aa)
	G3XRC1_ASPNA	MCM domain-containing protein; Belongs to the MCM family. (2047 aa)
	G3XPL3_ASPNA	DNA helicase; Belongs to the MCM family. (922 aa)
	G3XMY2_ASPNA	DNA helicase; Belongs to the MCM family. (851 aa)
	G3XLL3_ASPNA	Uncharacterized protein. (235 aa)
	G3XLK7_ASPNA	TFIIH basal transcription factor complex, subunit SSL2/RAD25. (825 aa)
	G3XT02_ASPNA	Uncharacterized protein. (541 aa)
	G3XT30_ASPNA	Sld5 domain-containing protein. (223 aa)
	G3XTS3_ASPNA	MgsA_C domain-containing protein. (56 aa)
	G3XTW0_ASPNA	Uncharacterized protein. (95 aa)
	G3XV11_ASPNA	Uncharacterized protein. (1588 aa)
	G3XVJ4_ASPNA	DNA helicase; Belongs to the MCM family. (1028 aa)
	G3XVU1_ASPNA	Thermolysin. (369 aa)
	G3XXY5_ASPNA	SAP domain-containing protein. (639 aa)

Your Current Organism:

Aspergillus niger

NCBI taxonomy Id: 380704
Other names: A. niger ATCC 1015, Aspergillus niger ATCC 1015

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G3XLK7_ASPNA	G3XV11_ASPNA	G3XLK7	G3XV11	TFIIH basal transcription factor complex, subunit SSL2/RAD25.	Uncharacterized protein.	0.490
G3XLK7_ASPNA	G3Y383_ASPNA	G3XLK7	G3Y383	TFIIH basal transcription factor complex, subunit SSL2/RAD25.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.737
G3XLK7_ASPNA	G3Y4J0_ASPNA	G3XLK7	G3Y4J0	TFIIH basal transcription factor complex, subunit SSL2/RAD25.	Uncharacterized protein.	0.490
G3XLK7_ASPNA	G3Y4M2_ASPNA	G3XLK7	G3Y4M2	TFIIH basal transcription factor complex, subunit SSL2/RAD25.	Uncharacterized protein.	0.493
G3XLK7_ASPNA	G3YC22_ASPNA	G3XLK7	G3YC22	TFIIH basal transcription factor complex, subunit SSL2/RAD25.	ATP-dependent DNA helicase-like protein.	0.971
G3XLK7_ASPNA	G3YEQ3_ASPNA	G3XLK7	G3YEQ3	TFIIH basal transcription factor complex, subunit SSL2/RAD25.	DNA repair helicase, subunit of TFIIH.	0.997
G3XLL3_ASPNA	G3XS56_ASPNA	G3XLL3	G3XS56	Uncharacterized protein.	Uncharacterized protein.	0.475
G3XLL3_ASPNA	G3XSC3_ASPNA	G3XLL3	G3XSC3	Uncharacterized protein.	Uncharacterized protein.	0.479
G3XLL3_ASPNA	G3XT02_ASPNA	G3XLL3	G3XT02	Uncharacterized protein.	Uncharacterized protein.	0.670
G3XLL3_ASPNA	G3XXY5_ASPNA	G3XLL3	G3XXY5	Uncharacterized protein.	SAP domain-containing protein.	0.549
G3XLL3_ASPNA	G3XYX7_ASPNA	G3XLL3	G3XYX7	Uncharacterized protein.	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase.	0.457
G3XLL3_ASPNA	G3XZR3_ASPNA	G3XLL3	G3XZR3	Uncharacterized protein.	EthD domain-containing protein.	0.475
G3XLL3_ASPNA	G3Y383_ASPNA	G3XLL3	G3Y383	Uncharacterized protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.671
G3XLL3_ASPNA	G3YA68_ASPNA	G3XLL3	G3YA68	Uncharacterized protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.475
G3XLL3_ASPNA	G3YC22_ASPNA	G3XLL3	G3YC22	Uncharacterized protein.	ATP-dependent DNA helicase-like protein.	0.469
G3XLL3_ASPNA	G3YCV4_ASPNA	G3XLL3	G3YCV4	Uncharacterized protein.	RecQ family helicase MusN.	0.475
G3XLL3_ASPNA	G3YEQ3_ASPNA	G3XLL3	G3YEQ3	Uncharacterized protein.	DNA repair helicase, subunit of TFIIH.	0.503
G3XMY2_ASPNA	G3XPL3_ASPNA	G3XMY2	G3XPL3	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
G3XMY2_ASPNA	G3XRC1_ASPNA	G3XMY2	G3XRC1	DNA helicase; Belongs to the MCM family.	MCM domain-containing protein; Belongs to the MCM family.	0.999
G3XMY2_ASPNA	G3XS56_ASPNA	G3XMY2	G3XS56	DNA helicase; Belongs to the MCM family.	Uncharacterized protein.	0.519