STRINGSTRING
prpB prpB prpC1 prpC1 acnM acnM h16_A1908 h16_A1908 prpD1 prpD1 prpC2 prpC2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
prpBMethylisocitric acid lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (302 aa)
prpC12-Methylcitrate synthase 1; Belongs to the citrate synthase family. (385 aa)
acnMMethyl-cis-aconitic acid hydratase/Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (870 aa)
h16_A1908Conserved hypothetical protein; Function unknown. (396 aa)
prpD12-Methylcitrate dehydratase. (484 aa)
prpC22-Methylcitrate synthase 2; Belongs to the citrate synthase family. (398 aa)
Your Current Organism:
Cupriavidus necator
NCBI taxonomy Id: 381666
Other names: Alcaligenes eutropha H16, C. necator H16, Cupriavidus necator ATCC 17699, Cupriavidus necator H16, Ralstonia eutropha ATCC 17699, Ralstonia eutropha H16, Ralstonia eutropha str. H16, Ralstonia eutropha strain H16, Wautersia eutropha H16
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