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bhmT bhmT metH metH metX metX metW metW ahcY ahcY h16_A0246 h16_A0246 cysK1 cysK1 cysE cysE cysS cysS metY1 metY1 metC metC cysK2 cysK2 thrC thrC thrA thrA metB metB thrB thrB metE metE metY2 metY2 cysK4 cysK4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
bhmTBetainehomocysteine S-methyltransferase. (319 aa)
metHMethionine synthase, cobalamine dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (915 aa)
metXHomoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. (393 aa)
metWMethionine biosynthesis protein MetW. (203 aa)
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (472 aa)
h16_A02465,10-Methylenetetrahydrofolate reductase; Deleted EC_number 1.7.99.5; Belongs to the methylenetetrahydrofolate reductase family. (276 aa)
cysK1Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (300 aa)
cysESerine acetyltransferase; CysE. (247 aa)
cysSCysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (462 aa)
metY1O-Acetylhomoserine sulfhydrylase. (436 aa)
metCCystathionine beta-lyase. (407 aa)
cysK2Cysteine synthase. (333 aa)
thrCThreonine synthase. (481 aa)
thrAHomoserine dehydrogenase. (436 aa)
metBCystathionine gamma-synthase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (401 aa)
thrBHomoserine kinase type II (protein kinase fold); Belongs to the pseudomonas-type ThrB family. (331 aa)
metEMethionine synthase II, cobalamin-independent; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (792 aa)
metY2O-Acetylhomoserine sulfhydrylase. (424 aa)
cysK4Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (305 aa)
Your Current Organism:
Cupriavidus necator
NCBI taxonomy Id: 381666
Other names: Alcaligenes eutropha H16, C. necator H16, Cupriavidus necator ATCC 17699, Cupriavidus necator H16, Ralstonia eutropha ATCC 17699, Ralstonia eutropha H16, Ralstonia eutropha str. H16, Ralstonia eutropha strain H16, Wautersia eutropha H16
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