(6 nodes) Heavy metal sensor kinase, and Transcriptional regulatory protein PcoR, heavy metal response network (Cupriavidus necator)

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Your Input:
	czrR	Response regulator involved in heavy metal response, OmpR-family; REC (residues 3 to 113, 4e-24) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105). (227 aa)
	czrS	Signal transduction histidine kinase, heavy metal sensor; Member of a two-component regulatory system. (472 aa)
	h16_B1646	Signal transduction histidine kinase; Member of a two-component regulatory system. (485 aa)
	h16_B1647	Response regulator, OmpR-family; REC (residues 3 to 114, 2e-25) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105). (229 aa)
	copR	Response regulator of copper response,OmpR-family; REC (residues 3 to 115, 1e-23) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105). (231 aa)
	copS	Signal transduction histidine kinase, copper sensor; Member of a two-component regulatory system. (459 aa)

Your Current Organism:

Cupriavidus necator

NCBI taxonomy Id: 381666
Other names: Alcaligenes eutropha H16, C. necator H16, Cupriavidus necator ATCC 17699, Cupriavidus necator H16, Ralstonia eutropha ATCC 17699, Ralstonia eutropha H16, Ralstonia eutropha str. H16, Ralstonia eutropha strain H16, Wautersia eutropha H16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
copR	copS	H16_B2186	H16_B2187	Response regulator of copper response,OmpR-family; REC (residues 3 to 115, 1e-23) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	Signal transduction histidine kinase, copper sensor; Member of a two-component regulatory system.	0.999
copR	czrR	H16_B2186	H16_A2167	Response regulator of copper response,OmpR-family; REC (residues 3 to 115, 1e-23) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	Response regulator involved in heavy metal response, OmpR-family; REC (residues 3 to 113, 4e-24) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	0.903
copR	czrS	H16_B2186	H16_A2168	Response regulator of copper response,OmpR-family; REC (residues 3 to 115, 1e-23) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	Signal transduction histidine kinase, heavy metal sensor; Member of a two-component regulatory system.	0.986
copR	h16_B1646	H16_B2186	H16_B1646	Response regulator of copper response,OmpR-family; REC (residues 3 to 115, 1e-23) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	Signal transduction histidine kinase; Member of a two-component regulatory system.	0.986
copR	h16_B1647	H16_B2186	H16_B1647	Response regulator of copper response,OmpR-family; REC (residues 3 to 115, 1e-23) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	Response regulator, OmpR-family; REC (residues 3 to 114, 2e-25) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	0.902
copS	copR	H16_B2187	H16_B2186	Signal transduction histidine kinase, copper sensor; Member of a two-component regulatory system.	Response regulator of copper response,OmpR-family; REC (residues 3 to 115, 1e-23) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	0.999
copS	czrR	H16_B2187	H16_A2167	Signal transduction histidine kinase, copper sensor; Member of a two-component regulatory system.	Response regulator involved in heavy metal response, OmpR-family; REC (residues 3 to 113, 4e-24) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	0.986
copS	czrS	H16_B2187	H16_A2168	Signal transduction histidine kinase, copper sensor; Member of a two-component regulatory system.	Signal transduction histidine kinase, heavy metal sensor; Member of a two-component regulatory system.	0.921
copS	h16_B1646	H16_B2187	H16_B1646	Signal transduction histidine kinase, copper sensor; Member of a two-component regulatory system.	Signal transduction histidine kinase; Member of a two-component regulatory system.	0.915
copS	h16_B1647	H16_B2187	H16_B1647	Signal transduction histidine kinase, copper sensor; Member of a two-component regulatory system.	Response regulator, OmpR-family; REC (residues 3 to 114, 2e-25) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	0.986
czrR	copR	H16_A2167	H16_B2186	Response regulator involved in heavy metal response, OmpR-family; REC (residues 3 to 113, 4e-24) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	Response regulator of copper response,OmpR-family; REC (residues 3 to 115, 1e-23) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	0.903
czrR	copS	H16_A2167	H16_B2187	Response regulator involved in heavy metal response, OmpR-family; REC (residues 3 to 113, 4e-24) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	Signal transduction histidine kinase, copper sensor; Member of a two-component regulatory system.	0.986
czrR	czrS	H16_A2167	H16_A2168	Response regulator involved in heavy metal response, OmpR-family; REC (residues 3 to 113, 4e-24) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	Signal transduction histidine kinase, heavy metal sensor; Member of a two-component regulatory system.	0.996
czrR	h16_B1646	H16_A2167	H16_B1646	Response regulator involved in heavy metal response, OmpR-family; REC (residues 3 to 113, 4e-24) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	Signal transduction histidine kinase; Member of a two-component regulatory system.	0.986
czrR	h16_B1647	H16_A2167	H16_B1647	Response regulator involved in heavy metal response, OmpR-family; REC (residues 3 to 113, 4e-24) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	Response regulator, OmpR-family; REC (residues 3 to 114, 2e-25) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	0.903
czrS	copR	H16_A2168	H16_B2186	Signal transduction histidine kinase, heavy metal sensor; Member of a two-component regulatory system.	Response regulator of copper response,OmpR-family; REC (residues 3 to 115, 1e-23) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	0.986
czrS	copS	H16_A2168	H16_B2187	Signal transduction histidine kinase, heavy metal sensor; Member of a two-component regulatory system.	Signal transduction histidine kinase, copper sensor; Member of a two-component regulatory system.	0.921
czrS	czrR	H16_A2168	H16_A2167	Signal transduction histidine kinase, heavy metal sensor; Member of a two-component regulatory system.	Response regulator involved in heavy metal response, OmpR-family; REC (residues 3 to 113, 4e-24) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	0.996
czrS	h16_B1646	H16_A2168	H16_B1646	Signal transduction histidine kinase, heavy metal sensor; Member of a two-component regulatory system.	Signal transduction histidine kinase; Member of a two-component regulatory system.	0.924
czrS	h16_B1647	H16_A2168	H16_B1647	Signal transduction histidine kinase, heavy metal sensor; Member of a two-component regulatory system.	Response regulator, OmpR-family; REC (residues 3 to 114, 2e-25) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	0.985

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