STRINGSTRING
h16_A0226 h16_A0226 h16_A0310 h16_A0310 rfbB1 rfbB1 h16_A0455 h16_A0455 gdpD gdpD ppa ppa h16_A0997 h16_A0997 phnP phnP h16_A1209 h16_A1209 h16_A1211 h16_A1211 h16_A1212 h16_A1212 h16_A1213 h16_A1213 h16_A1271 h16_A1271 h16_A1298 h16_A1298 h16_A1538 h16_A1538 h16_A1979 h16_A1979 h16_A2182 h16_A2182 h16_A2183 h16_A2183 pitA pitA h16_A2274 h16_A2274 ugpQ ugpQ ppx ppx ppk1 ppk1 phoR phoR phoB phoB phoU phoU pstB pstB pstA pstA pstC pstC pstS pstS h16_A2633 h16_A2633 h16_A2731 h16_A2731 h16_A2797 h16_A2797 h16_A2798 h16_A2798 h16_A2975 h16_A2975 h16_A2976 h16_A2976 pldB pldB ompW3 ompW3 h16_B0054 h16_B0054 ompW2 ompW2 eutB eutB eutC eutC phnE2 phnE2 phnE2-2 phnE2-2 phnC2 phnC2 phnD2 phnD2 h16_B0320 h16_B0320 h16_B0514 h16_B0514 poxR poxR h16_B0588 h16_B0588 h16_B0831 h16_B0831 phnB phnB h16_B0833 h16_B0833 phnA phnA phoD phoD ppk2 ppk2 phnM phnM phnL phnL phnK phnK phnJ phnJ phnI phnI phnH1 phnH1 phnG phnG phnF phnF h16_B1290 h16_B1290 phnN phnN phnT phnT phnH2 phnH2 phnE1 phnE1 phnD1 phnD1 phnC1 phnC1 h16_B1531 h16_B1531 h16_B1947 h16_B1947 h16_B1948 h16_B1948 h16_B1953 h16_B1953 h16_B1954 h16_B1954
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
h16_A0226Conserved hypothetical protein. (269 aa)
h16_A0310Transcriptional regulator, GntR-family. (240 aa)
rfbB1dTDP-D-glucose 4,6-dehydratase. (616 aa)
h16_A0455dATP pyrophosphohydrolase. (162 aa)
gdpDGlycerophosphoryl diester phosphodiesterase. (410 aa)
ppaInorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. (175 aa)
h16_A0997Conserved hypothetical protein. (305 aa)
phnPMetal-dependent hydrolase of the beta-lactamase superfamily I. (262 aa)
h16_A1209Conserved hypothetical protein. (349 aa)
h16_A1211Universal stress protein, UspA family. (144 aa)
h16_A1212Conserved hypothetical protein. (370 aa)
h16_A1213Conserved hypothetical protein; Function unknown. (71 aa)
h16_A1271Conserved hypothetical protein. (294 aa)
h16_A1298Transcriptional regulator, GntR-family. (263 aa)
h16_A1538Transcriptional regulator, GntR-family. (260 aa)
h16_A1979Conserved hypothetical protein. (265 aa)
h16_A2182Alkaline phosphatase; Belongs to the alkaline phosphatase family. (462 aa)
h16_A2183Alkaline phosphatase; Unknown EC_number=3.1.3.1-; Belongs to the alkaline phosphatase family. (483 aa)
pitALow-affinity inorganic phosphate transporter; 8 TMHs. (335 aa)
h16_A2274Predicted Phosphate transport regulator. (208 aa)
ugpQGlycerophosphoryl diester phosphodiesterase. (248 aa)
ppxExopolyphosphatase. (510 aa)
ppk1Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (695 aa)
phoRSignal transduction histidine kinase, phosphate regulon sensor PhoR. (460 aa)
phoBResponse regulator, phosphate regulon transcriptional regulator PhoB, OmpR-family; REC (residues 5 to 119, 2e-26) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105). (235 aa)
phoUPhosphate uptake regulator PhoU; Plays a role in the regulation of phosphate uptake. (234 aa)
pstBABC-type transporter, ATPase component: PhoT family; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (262 aa)
pstAABC-type transporter, permease component: PhoT family; 6 TMHs. (299 aa)
pstCABC-type transporter, permease component: PhoT family; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (322 aa)
pstSABC-type transporter, periplasmic component: PhoT family; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. (343 aa)
h16_A2633Transcriptional regulator, GntR-family. (293 aa)
h16_A2731Uncharacterized conserved protein; Converts GTP to 7,8-dihydroneopterin triphosphate. (267 aa)
h16_A2797Hemerythrin. (146 aa)
h16_A2798Conserved hypothetical protein. (192 aa)
h16_A2975Conserved hypothetical protein; Function unknown. (160 aa)
h16_A2976Predicted permease; 8 TMHs. (274 aa)
pldBLysophospholipase. (310 aa)
ompW3Porin, OmpW family. (279 aa)
h16_B0054Transcriptional regulator, GntR-family. (261 aa)
ompW2Porin, OmpW family. (214 aa)
eutBEthanolamine ammonia-lyase heavy chain. (460 aa)
eutCEthanolamine ammonia-lyase light chain; Belongs to the EutC family. (261 aa)
phnE2ABC-type transporter, permease component: PhnT family; 6 TMHs. (251 aa)
phnE2-2ABC-type transporter, permease component; 5 TMHs. (273 aa)
phnC2ABC-type transporter, ATPase component: PhnT family; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family. (280 aa)
phnD2ABC-type transporter, periplasmic component: PhnT family. (282 aa)
h16_B0320Transcriptional regulator, DeoR-family. (259 aa)
h16_B0514Transcriptional regulator, GntR-family. (249 aa)
poxRActivator of phenol-degradative genes,PspF-family. (575 aa)
h16_B0588Transcriptional regulator, GntR-family. (258 aa)
h16_B0831Alcohol dehydrogenase, class IV. (363 aa)
phnB2-Phosphonopropionate transporter, MFS-type,OPAfamily; 12 TMHs. (434 aa)
h16_B0833NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (481 aa)
phnAPhosphonoacetate hydrolase. (406 aa)
phoDPhosphodiesterase/alkaline phosphatase D. (669 aa)
ppk2Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (711 aa)
phnMMetal-dependent hydrolase involved in phosphonate metabolism. (405 aa)
phnLABC-type phosphonate transport system, ATPase component. (242 aa)
phnKABC-type phosphonate transport system, ATPase component; Belongs to the ABC transporter superfamily. (258 aa)
phnJUncharacterized enzyme of phosphonate metabolism; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. Belongs to the PhnJ family. (300 aa)
phnIUncharacterized enzyme of phosphonate metabolism. (372 aa)
phnH1Bacterial phosphonate metabolism protein. (205 aa)
phnGUncharacterized enzyme of phosphonate metabolism. (161 aa)
phnFRegulator of phosphonate operon, GntR-family. (244 aa)
h16_B1290Conserved hypothetical protein. (241 aa)
phnNUncharacterized component of phosphonate metabolism; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). (196 aa)
phnTAcetyltransferase (GNAT) family. (154 aa)
phnH2Predicted HD phosphohydrolase. (178 aa)
phnE1ABC-type transporter, permease component: PhnT family; 6 TMHs. (270 aa)
phnD1ABC-type transporter, periplasmic component: PhnT family. (330 aa)
phnC1ABC-type transporter, ATPase component: PhnT family; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family. (284 aa)
h16_B1531Transcriptional regulator, GntR-family. (236 aa)
h16_B1947Glyceraldehyde-3 dehydrogenase; Belongs to the aldehyde dehydrogenase family. (487 aa)
h16_B1948Phosphonoacetate hydrolase. (420 aa)
h16_B1953(2-aminoethyl) phosphonate--pyruvate transaminase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily. (377 aa)
h16_B1954Hypothetical membrane protein. (268 aa)
Your Current Organism:
Cupriavidus necator
NCBI taxonomy Id: 381666
Other names: Alcaligenes eutropha H16, C. necator H16, Cupriavidus necator ATCC 17699, Cupriavidus necator H16, Ralstonia eutropha ATCC 17699, Ralstonia eutropha H16, Ralstonia eutropha str. H16, Ralstonia eutropha strain H16, Wautersia eutropha H16
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