(26 nodes) OmpR/PhoB-type DNA-binding domain network (Cupriavidus necator)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	h16_A1278	ATP-dependent transcriptional regulator containing adenylate cyclase related domains. (1304 aa)
	h16_A3726	Response regulator, OmpR-family; REC (residues 3 to 115, 4e-24) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105). (224 aa)
	phhR	Response regulator, OmpR-family; REC (residues 3 to 115, 2e-22) with a complete phosphorylation pocket (DD-D55-S85-K96). (234 aa)
	h16_A2599	Response regulator, OmpR-family; REC (residues 9 to 119, 3e-24) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105). (231 aa)
	phoB	Response regulator, phosphate regulon transcriptional regulator PhoB, OmpR-family; REC (residues 5 to 119, 2e-26) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105). (235 aa)
	h16_A2379	Response regulator, OmpR-family; REC (residues 3 to 115, 2e-25) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105). (224 aa)
	czrR	Response regulator involved in heavy metal response, OmpR-family; REC (residues 3 to 113, 4e-24) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105). (227 aa)
	h16_A1818	Response regulator, OmpR-family; REC (residues 5 to 117, 5e-26) with a complete phosphorylation pocket (DD-D55-T96-K108). (232 aa)
	h16_A1757	Response regulator, OmpR-family; REC (residues 8 to 121, 6e-25) with a complete phosphorylation pocket (DD-D55-T82-K97). (204 aa)
	h16_B0894	Response regulator; REC (residues 9 to 120, 1e-25) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105); response regulator, OmpR-family. (231 aa)
	h16_B1245	Response regulator, OmpR-family; REC (residues 3 to 115, 3e-26) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105). (224 aa)
	h16_A1463	Response regulator, OmpR-family; REC (residues 8 to 120, 9e-31) with a complete phosphorylation pocket (DD-D55-T75-K96). (240 aa)
	h16_A1427	Response regulator, OmpR-family; REC (residues 3 to 114, 1e-23) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105). (223 aa)
	h16_A0586	Response regulator, OmpR-family; REC (residues 9 to 121, 1e-27) with a complete phosphorylation pocket (DD-D55-S78-K96). (247 aa)
	h16_A0543	Response regulator, OmpR-family; REC (residues 3 to 115, 8e-25) with a complete phosphorylation pocket (DD-D48-S79-K96). (229 aa)
	h16_A0295	Response regulator, OmpR-family; REC (residues 9 to 120, 7e-24) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105). (232 aa)
	h16_A0081	Response regulator, OmpR-family; REC (residues 11 to 122, 5e-19) with a typical phosphorylation pocket (DD,D54,S/T82,K105). (245 aa)
	h16_A0080	Response regulator, OmpR-family; REC (residues 8 to 116, 2e-12) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105). (226 aa)
	h16_B2563	Response regulator, OmpR-family; REC (residues 3 to 120, 2e-24) with a complete phosphorylation pocket (DD-D53-T80-K101). (237 aa)
	h16_B2197	Response regulator, OmpR-family; REC (residues 5 to 116, 5e-24) with a complete phosphorylation pocket (DD-D46-S80-K95). (242 aa)
	copR	Response regulator of copper response,OmpR-family; REC (residues 3 to 115, 1e-23) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105). (231 aa)
	h16_B2094	Response regulator, OmpR-family; REC (residues 12 to 123, 1e-23) with a complete phosphorylation pocket (DD-D53-T74-K103). (240 aa)
	h16_B1785	Response regulator, OmpR-family; REC (residues 8 to 121, 4e-25) with a complete phosphorylation pocket (DD-D55-T82-K109). (247 aa)
	h16_B1647	Response regulator, OmpR-family; REC (residues 3 to 114, 2e-25) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105). (229 aa)
	h16_B1424	Transcriptional regulator, CadC-family. (515 aa)
	h16_B1254	Response regulator, OmpR-family; REC (residues 17 to 115, 3e-13) with an incomplete phosphorylation pocket (only D54). (251 aa)

Your Current Organism:

Cupriavidus necator

NCBI taxonomy Id: 381666
Other names: Alcaligenes eutropha H16, C. necator H16, Cupriavidus necator ATCC 17699, Cupriavidus necator H16, Ralstonia eutropha ATCC 17699, Ralstonia eutropha H16, Ralstonia eutropha str. H16, Ralstonia eutropha strain H16, Wautersia eutropha H16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
copR	czrR	H16_B2186	H16_A2167	Response regulator of copper response,OmpR-family; REC (residues 3 to 115, 1e-23) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	Response regulator involved in heavy metal response, OmpR-family; REC (residues 3 to 113, 4e-24) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	0.903
copR	h16_B1647	H16_B2186	H16_B1647	Response regulator of copper response,OmpR-family; REC (residues 3 to 115, 1e-23) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	Response regulator, OmpR-family; REC (residues 3 to 114, 2e-25) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	0.902
czrR	copR	H16_A2167	H16_B2186	Response regulator involved in heavy metal response, OmpR-family; REC (residues 3 to 113, 4e-24) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	Response regulator of copper response,OmpR-family; REC (residues 3 to 115, 1e-23) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	0.903
czrR	h16_B1647	H16_A2167	H16_B1647	Response regulator involved in heavy metal response, OmpR-family; REC (residues 3 to 113, 4e-24) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	Response regulator, OmpR-family; REC (residues 3 to 114, 2e-25) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	0.903
h16_A0080	h16_A0081	H16_A0080	H16_A0081	Response regulator, OmpR-family; REC (residues 8 to 116, 2e-12) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	Response regulator, OmpR-family; REC (residues 11 to 122, 5e-19) with a typical phosphorylation pocket (DD,D54,S/T82,K105).	0.526
h16_A0080	h16_A1757	H16_A0080	H16_A1757	Response regulator, OmpR-family; REC (residues 8 to 116, 2e-12) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	Response regulator, OmpR-family; REC (residues 8 to 121, 6e-25) with a complete phosphorylation pocket (DD-D55-T82-K97).	0.766
h16_A0080	h16_B2094	H16_A0080	H16_B2094	Response regulator, OmpR-family; REC (residues 8 to 116, 2e-12) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	Response regulator, OmpR-family; REC (residues 12 to 123, 1e-23) with a complete phosphorylation pocket (DD-D53-T74-K103).	0.774
h16_A0081	h16_A0080	H16_A0081	H16_A0080	Response regulator, OmpR-family; REC (residues 11 to 122, 5e-19) with a typical phosphorylation pocket (DD,D54,S/T82,K105).	Response regulator, OmpR-family; REC (residues 8 to 116, 2e-12) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	0.526
h16_A1278	h16_B1424	H16_A1278	H16_B1424	ATP-dependent transcriptional regulator containing adenylate cyclase related domains.	Transcriptional regulator, CadC-family.	0.406
h16_A1757	h16_A0080	H16_A1757	H16_A0080	Response regulator, OmpR-family; REC (residues 8 to 121, 6e-25) with a complete phosphorylation pocket (DD-D55-T82-K97).	Response regulator, OmpR-family; REC (residues 8 to 116, 2e-12) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	0.766
h16_A2379	h16_A3726	H16_A2379	H16_A3726	Response regulator, OmpR-family; REC (residues 3 to 115, 2e-25) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	Response regulator, OmpR-family; REC (residues 3 to 115, 4e-24) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	0.904
h16_A2599	h16_B0894	H16_A2599	H16_B0894	Response regulator, OmpR-family; REC (residues 9 to 119, 3e-24) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	Response regulator; REC (residues 9 to 120, 1e-25) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105); response regulator, OmpR-family.	0.900
h16_A3726	h16_A2379	H16_A3726	H16_A2379	Response regulator, OmpR-family; REC (residues 3 to 115, 4e-24) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	Response regulator, OmpR-family; REC (residues 3 to 115, 2e-25) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	0.904
h16_B0894	h16_A2599	H16_B0894	H16_A2599	Response regulator; REC (residues 9 to 120, 1e-25) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105); response regulator, OmpR-family.	Response regulator, OmpR-family; REC (residues 9 to 119, 3e-24) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	0.900
h16_B1424	h16_A1278	H16_B1424	H16_A1278	Transcriptional regulator, CadC-family.	ATP-dependent transcriptional regulator containing adenylate cyclase related domains.	0.406
h16_B1647	copR	H16_B1647	H16_B2186	Response regulator, OmpR-family; REC (residues 3 to 114, 2e-25) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	Response regulator of copper response,OmpR-family; REC (residues 3 to 115, 1e-23) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	0.902
h16_B1647	czrR	H16_B1647	H16_A2167	Response regulator, OmpR-family; REC (residues 3 to 114, 2e-25) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	Response regulator involved in heavy metal response, OmpR-family; REC (residues 3 to 113, 4e-24) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	0.903
h16_B2094	h16_A0080	H16_B2094	H16_A0080	Response regulator, OmpR-family; REC (residues 12 to 123, 1e-23) with a complete phosphorylation pocket (DD-D53-T74-K103).	Response regulator, OmpR-family; REC (residues 8 to 116, 2e-12) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105).	0.774

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