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phoB phoB wzc wzc wzb wzb cheB1 cheB1 fliM fliM ntrC ntrC cheB2 cheB2 prkA prkA phoR phoR
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
phoBResponse regulator, phosphate regulon transcriptional regulator PhoB, OmpR-family; REC (residues 5 to 119, 2e-26) with a typical phosphorylation pocket (1/2 DD,D54,S/T82,K105). (235 aa)
wzcProtein tyrosin kinase involved in exopolysaccharide biosynthesis. (740 aa)
wzbProtein-tyrosine phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (155 aa)
cheB1Chemotaxis specific response regulator containing a methylesterase domain; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (360 aa)
fliMFlagellar motor switch protein. (339 aa)
ntrCResponse regulator, nitrogen regulation protein NtrC; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (515 aa)
cheB2Chemotaxis response regulator containing a methylesterase domain; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (339 aa)
prkASerine protein kinase; Deleted EC_number 2.7.1.37. (640 aa)
phoRSignal transduction histidine kinase, phosphate regulon sensor PhoR. (460 aa)
Your Current Organism:
Cupriavidus necator
NCBI taxonomy Id: 381666
Other names: Alcaligenes eutropha H16, C. necator H16, Cupriavidus necator ATCC 17699, Cupriavidus necator H16, Ralstonia eutropha ATCC 17699, Ralstonia eutropha H16, Ralstonia eutropha str. H16, Ralstonia eutropha strain H16, Wautersia eutropha H16
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