(33 nodes) (2021) Investigation of the Physiology of the Obligate Alkaliphilic Bacillus marmarensis GMBE 72(T) Considering Its Alkaline Adaptation Mechanism for Poly(3-hydroxybutyrate) Synthesis. network (Cupriavidus necator)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	h16_B0699	Acyl-CoA dehydrogenase, long-chain specific. (378 aa)
	h16_A0101	Acyl-CoA dehydrogenase. (784 aa)
	paaH1	3-Hydroxyacyl-CoA dehydrogenase. (284 aa)
	h16_A0461	Two domain protein: 3-hydroxyacyl-CoA dehydrogenase. (807 aa)
	h16_A1091	FadE2-like Acyl-CoA dehydrogenase (ACAD). (420 aa)
	paaH2	3-Hydroxyacyl-CoA dehydrogenase. (507 aa)
	h16_A1291	Isovaleryl-CoA dehydrogenase. (379 aa)
	phaC1	Poly(3-hydroxybutyrate) polymerase; Polymerizes (R)-3-hydroxybutyryl-CoA to create polyhydroxybutyrate (PHB) which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation; Belongs to the PHA/PHB synthase family. Type I PhaC subfamily. (589 aa)
	h16_A1526	Enoyl-CoA hydratase/Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase. (693 aa)
	h16_A2076	Long-chain-fatty-acid--CoA ligase. (516 aa)
	h16_A2150	Long-chain-fatty-acid--CoA ligase. (513 aa)
	abmD	Putative acyl-CoA dehydrogenase. (389 aa)
	h16_A2596	Acyl-CoA dehydrogenase. (388 aa)
	h16_A2748	Long-chain-fatty-acid-CoA ligase; Catalyzes the CoA- and ATP-dependent conversion of sulfoacetate to sulfoacetyl-CoA and AMP; Belongs to the ATP-dependent AMP-binding enzyme family. (509 aa)
	h16_A2947	Long chain fatty acid-CoA ligase. (577 aa)
	fadD3	Long-chain-fatty-acid-CoA ligase. (560 aa)
	h16_A3351	Long-chain-fatty-acid-CoA ligase. (497 aa)
	h16_A3514	Long-chain-fatty-acid-CoA ligase. (557 aa)
	atpC	Membrane-bound ATP synthase, F1 sector,epsilon-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (138 aa)
	h16_B0014	Acyl-CoA dehydrogenase, short-chain specific. (399 aa)
	h16_B0087	Acyl-CoA dehydrogenase. (598 aa)
	h16_B0683	Acyl-CoA dehydrogenase. (389 aa)
	h16_B0703	Acyl-CoA dehydrogenase. (332 aa)
	h16_B0721	Acyl-CoA dehydrogenase. (379 aa)
	h16_B0722	Acyl-CoA dehydrogenase. (394 aa)
	h16_B0724	Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family. (692 aa)
	h16_B0753	Long-chain-fatty-acid--CoA ligase. (515 aa)
	h16_B0913	Acyl-CoA dehydrogenase. (388 aa)
	h16_B1239	Long-chain-fatty-acid--CoA ligase. (582 aa)
	h16_B1367	Acyl-CoA dehydrogenase. (388 aa)
	h16_B1736	Long-chain-fatty-acid-CoA ligase. (577 aa)
	h16_B1826	Acyl-CoA dehydrogenase. (397 aa)
	h16_B2157	Acyl-CoA dehydrogenase. (385 aa)

Your Current Organism:

Cupriavidus necator

NCBI taxonomy Id: 381666
Other names: Alcaligenes eutropha H16, C. necator H16, Cupriavidus necator ATCC 17699, Cupriavidus necator H16, Ralstonia eutropha ATCC 17699, Ralstonia eutropha H16, Ralstonia eutropha str. H16, Ralstonia eutropha strain H16, Wautersia eutropha H16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
abmD	fadD3	H16_A2458	H16_A3288	Putative acyl-CoA dehydrogenase.	Long-chain-fatty-acid-CoA ligase.	0.467
abmD	h16_A0461	H16_A2458	H16_A0461	Putative acyl-CoA dehydrogenase.	Two domain protein: 3-hydroxyacyl-CoA dehydrogenase.	0.880
abmD	h16_A1526	H16_A2458	H16_A1526	Putative acyl-CoA dehydrogenase.	Enoyl-CoA hydratase/Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase.	0.819
abmD	h16_A2076	H16_A2458	H16_A2076	Putative acyl-CoA dehydrogenase.	Long-chain-fatty-acid--CoA ligase.	0.652
abmD	h16_A2150	H16_A2458	H16_A2150	Putative acyl-CoA dehydrogenase.	Long-chain-fatty-acid--CoA ligase.	0.652
abmD	h16_A2748	H16_A2458	H16_A2748	Putative acyl-CoA dehydrogenase.	Long-chain-fatty-acid-CoA ligase; Catalyzes the CoA- and ATP-dependent conversion of sulfoacetate to sulfoacetyl-CoA and AMP; Belongs to the ATP-dependent AMP-binding enzyme family.	0.651
abmD	h16_A2947	H16_A2458	H16_A2947	Putative acyl-CoA dehydrogenase.	Long chain fatty acid-CoA ligase.	0.652
abmD	h16_A3351	H16_A2458	H16_A3351	Putative acyl-CoA dehydrogenase.	Long-chain-fatty-acid-CoA ligase.	0.652
abmD	h16_A3514	H16_A2458	H16_A3514	Putative acyl-CoA dehydrogenase.	Long-chain-fatty-acid-CoA ligase.	0.652
abmD	h16_B0724	H16_A2458	H16_B0724	Putative acyl-CoA dehydrogenase.	Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family.	0.773
abmD	h16_B0753	H16_A2458	H16_B0753	Putative acyl-CoA dehydrogenase.	Long-chain-fatty-acid--CoA ligase.	0.652
abmD	h16_B1239	H16_A2458	H16_B1239	Putative acyl-CoA dehydrogenase.	Long-chain-fatty-acid--CoA ligase.	0.652
abmD	h16_B1736	H16_A2458	H16_B1736	Putative acyl-CoA dehydrogenase.	Long-chain-fatty-acid-CoA ligase.	0.652
abmD	paaH1	H16_A2458	H16_A0282	Putative acyl-CoA dehydrogenase.	3-Hydroxyacyl-CoA dehydrogenase.	0.453
abmD	paaH2	H16_A2458	H16_A1102	Putative acyl-CoA dehydrogenase.	3-Hydroxyacyl-CoA dehydrogenase.	0.515
fadD3	abmD	H16_A3288	H16_A2458	Long-chain-fatty-acid-CoA ligase.	Putative acyl-CoA dehydrogenase.	0.467
fadD3	h16_A0101	H16_A3288	H16_A0101	Long-chain-fatty-acid-CoA ligase.	Acyl-CoA dehydrogenase.	0.467
fadD3	h16_A0461	H16_A3288	H16_A0461	Long-chain-fatty-acid-CoA ligase.	Two domain protein: 3-hydroxyacyl-CoA dehydrogenase.	0.592
fadD3	h16_A1091	H16_A3288	H16_A1091	Long-chain-fatty-acid-CoA ligase.	FadE2-like Acyl-CoA dehydrogenase (ACAD).	0.467
fadD3	h16_A1291	H16_A3288	H16_A1291	Long-chain-fatty-acid-CoA ligase.	Isovaleryl-CoA dehydrogenase.	0.467

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