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glyA glyA Fnod_0088 Fnod_0088 Fnod_0230 Fnod_0230 Fnod_0261 Fnod_0261 Fnod_0486 Fnod_0486 Fnod_0559 Fnod_0559 Fnod_0587 Fnod_0587 Fnod_0595 Fnod_0595 prs prs tpiA tpiA pgk pgk Fnod_0740 Fnod_0740 Fnod_0761 Fnod_0761 Fnod_0772 Fnod_0772 Fnod_0790 Fnod_0790 Fnod_0808 Fnod_0808 glmS glmS Fnod_0869 Fnod_0869 pgi pgi Fnod_0882 Fnod_0882 Fnod_0902 Fnod_0902 fmt fmt def def Fnod_0958 Fnod_0958 Fnod_0971 Fnod_0971 gcvPB gcvPB gcvPA gcvPA gcvT gcvT Fnod_0985 Fnod_0985 gcvH gcvH Fnod_1064 Fnod_1064 fhs fhs tal tal Fnod_1279 Fnod_1279 thyX thyX folD folD Fnod_1343 Fnod_1343 Fnod_1351 Fnod_1351 Fnod_1449 Fnod_1449 deoC deoC pfp pfp Fnod_1641 Fnod_1641 pfkA pfkA Fnod_1680 Fnod_1680 eno eno
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (422 aa)
Fnod_0088PFAM: ROK family protein; KEGG: tpt:Tpet_1323 ROK family protein. (313 aa)
Fnod_0230TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; FAD dependent oxidoreductase; KEGG: tma:TM0381 dihydrolipoamide dehydrogenase. (454 aa)
Fnod_0261TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: tma:TM0943 glutamine synthetase. (439 aa)
Fnod_0486Phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: tma:TM0769 phosphomannomutase. (483 aa)
Fnod_0559PFAM: Nucleotidyl transferase; KEGG: tma:TM1033 mannose-1-phosphate guanylyltransferase. (323 aa)
Fnod_0587PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: efa:EF1586 NADH oxidase. (454 aa)
Fnod_0595PFAM: FAD dependent oxidoreductase; KEGG: drm:Dred_1730 FAD dependent oxidoreductase. (390 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (315 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (243 aa)
pgkPFAM: phosphoglycerate kinase; KEGG: tma:TM0689 phosphoglycerate kinase / triose-phosphate isomerase; Belongs to the phosphoglycerate kinase family. (400 aa)
Fnod_0740TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; KEGG: tma:TM0688 glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (332 aa)
Fnod_0761TIGRFAM: ketose-bisphosphate aldolase; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II; KEGG: tpt:Tpet_0651 fructose-1,6-bisphosphate aldolase, class II. (330 aa)
Fnod_0772PFAM: dihydropteroate synthase DHPS; homocysteine S-methyltransferase; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; KEGG: tma:TM0268 5-methyltetrahydrofolate S-homocysteine methyltransferase. (780 aa)
Fnod_0790TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase; KEGG: tpt:Tpet_1664 ribose 5-phosphate isomerase B. (145 aa)
Fnod_0808TIGRFAM: glutamate formiminotransferase; PFAM: Formiminotransferase domain protein; Formiminotransferase domain protein; KEGG: tma:TM0843 formiminotransferase- cyclodeaminase/formiminotetrahydrofolate cyclodeaminase, putative. (303 aa)
glmSGlucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (603 aa)
Fnod_0869PFAM: PfkB domain protein; KEGG: ctc:CTC00909 ribokinase; Belongs to the carbohydrate kinase PfkB family. (290 aa)
pgiPFAM: phosphoglucose isomerase (PGI); KEGG: tma:TM1385 glucose-6-phosphate isomerase; Belongs to the GPI family. (453 aa)
Fnod_0882PFAM: mannose-6-phosphate isomerase type I; KEGG: tma:TM0736 mannose-6-phosphate isomerase. (273 aa)
Fnod_0902PFAM: Formiminotransferase-cyclodeaminase; KEGG: tpt:Tpet_1232 formiminotransferase-cyclodeaminase. (208 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (310 aa)
defPeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (170 aa)
Fnod_0958PFAM: phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: cbo:CBO3619 phosphoglucomutase/phosphomannomutase. (574 aa)
Fnod_0971PFAM: PfkB domain protein; KEGG: tma:TM0828 sugar kinase, PfkB family. (318 aa)
gcvPBGlycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (477 aa)
gcvPAGlycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (441 aa)
gcvTGlycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (430 aa)
Fnod_0985PFAM: ribulose-phosphate 3-epimerase; KEGG: tpt:Tpet_1014 ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (212 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (120 aa)
Fnod_1064PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: tma:TM1015 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (427 aa)
fhsPFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: tma:TM1766 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (552 aa)
talPutative transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa)
Fnod_1279PFAM: methylenetetrahydrofolate reductase; KEGG: sru:SRU_2094 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (313 aa)
thyXThymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (233 aa)
folDTetrahydrofolate dehydrogenase/cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (272 aa)
Fnod_13436-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (333 aa)
Fnod_1351PFAM: PfkB domain protein; KEGG: deb:DehaBAV1_1157 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (309 aa)
Fnod_1449TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: swo:Swol_1787 glutamate--ammonia ligase. (456 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (241 aa)
pfpPhosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (422 aa)
Fnod_1641TIGRFAM: putative delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: drm:Dred_1731 putative delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (525 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (335 aa)
Fnod_1680PFAM: Transketolase domain protein; Transketolase central region; KEGG: tma:TM1762 transketolase. (623 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (431 aa)
Your Current Organism:
Fervidobacterium nodosum
NCBI taxonomy Id: 381764
Other names: F. nodosum Rt17-B1, Fervidobacterium nodosum Rt17-B1, Fervidobacterium nodosum str. Rt17-B1, Fervidobacterium nodosum strain Rt17-B1
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