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| | ndk | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (147 aa) |
| | Fnod_0043 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: tpt:Tpet_0515 thiamine pyrophosphate enzyme domain protein TPP-binding. (273 aa) |
| | Fnod_0044 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: tpt:Tpet_0514 pyruvate ferredoxin/flavodoxin oxidoreductase. (198 aa) |
| | Fnod_0045 | PFAM: diacylglycerol kinase; KEGG: tpt:Tpet_0513 diacylglycerol kinase. (153 aa) |
| | Fnod_0055 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: tpt:Tpet_1585 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (561 aa) |
| | Fnod_0056 | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: tpt:Tpet_1584 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit. (276 aa) |
| | Fnod_0063 | Aminotransferase class I and II; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; KEGG: cbo:CBO1804 aspartate aminotransferase. (396 aa) |
| | Fnod_0070 | TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; KEGG: tpt:Tpet_1269 aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (330 aa) |
| | Fnod_0071 | PFAM: diaminopimelate epimerase; KEGG: tma:TM1522 diaminopimelate epimerase; Belongs to the diaminopimelate epimerase family. (245 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (304 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (215 aa) |
| | dapH | Tetrahydrodipicolinate succinyltransferase domain protein; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (249 aa) |
| | Fnod_0075 | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; KEGG: tma:TM1518 aspartokinase II; Belongs to the aspartokinase family. (400 aa) |
| | Fnod_0076 | PFAM: aminotransferase class-III; KEGG: aae:aq_023 acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (377 aa) |
| | Fnod_0081 | TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: tma:TM1516 hydrolase, ama/HipO/HyuC family. (369 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (422 aa) |
| | Fnod_0088 | PFAM: ROK family protein; KEGG: tpt:Tpet_1323 ROK family protein. (313 aa) |
| | Fnod_0103 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: tma:TM1401 D-3-phosphoglycerate dehydrogenase. (303 aa) |
| | Fnod_0105 | Putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; KEGG: tma:TM1131 aminotransferase, putative. (411 aa) |
| | Fnod_0110 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: tma:TM1758 2-oxoisovalerate ferredoxin oxidoreductase, delta subunit. (76 aa) |
| | Fnod_0111 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: tpt:Tpet_1046 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (353 aa) |
| | Fnod_0112 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: tpt:Tpet_1047 thiamine pyrophosphate enzyme domain protein TPP-binding. (251 aa) |
| | Fnod_0113 | TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: tpt:Tpet_1048 pyruvate ferredoxin/flavodoxin oxidoreductase. (179 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (508 aa) |
| | metK | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (396 aa) |
| | Fnod_0198 | TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: tma:TM0804 histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (240 aa) |
| | Fnod_0217 | PFAM: GCN5-related N-acetyltransferase; aminotransferase class I and II; KEGG: cac:CAC2970 PLP-dependent aminotransferase. (521 aa) |
| | Fnod_0221 | PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: tpt:Tpet_0969 alpha amylase, catalytic region. (474 aa) |
| | Fnod_0230 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; FAD dependent oxidoreductase; KEGG: tma:TM0381 dihydrolipoamide dehydrogenase. (454 aa) |
| | Fnod_0263 | PFAM: alanine racemase domain protein; KEGG: tma:TM1597 hypothetical protein. (358 aa) |
| | Fnod_0264 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (267 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (308 aa) |
| | Fnod_0287 | PFAM: glycoside hydrolase family 3 domain protein; KEGG: tma:TM0025 beta-glucosidase; Belongs to the glycosyl hydrolase 3 family. (717 aa) |
| | glgA | Glycogen/starch synthase, ADP-glucose type; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (485 aa) |
| | Fnod_0313 | TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: tma:TM1724 3-oxoacyl-(acyl carrier protein) reductase. (239 aa) |
| | Fnod_0314 | TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: cps:CPS_2626 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa) |
| | Fnod_0316 | PFAM: Polyprenyl synthetase; KEGG: pto:PTO0848 geranylgeranyl pyrophosphate synthase. (341 aa) |
| | Fnod_0373 | Inosine guanosine and xanthosine phosphorylase family; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (278 aa) |
| | Fnod_0398 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase; cytidylyltransferase; KEGG: tpt:Tpet_0070 riboflavin biosynthesis protein RibF; Belongs to the ribF family. (289 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (393 aa) |
| | Fnod_0446 | Sucrose-phosphate synthase; PFAM: glycosyl transferase group 1; KEGG: pma:Pro1880 glycosyltransferase. (479 aa) |
| | Fnod_0464 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: tma:TM0665 cysteine synthase. (294 aa) |
| | Fnod_0465 | KEGG: tma:TM0666 serine acetyltransferase. (221 aa) |
| | Fnod_0486 | Phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: tma:TM0769 phosphomannomutase. (483 aa) |
| | Fnod_0520 | PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: tpt:Tpet_0380 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit. (160 aa) |
| | Fnod_0521 | TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; KEGG: tma:TM0540 fumarate hydratase alpha subunit. (277 aa) |
| | plsY | Protein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (215 aa) |
| | Fnod_0559 | PFAM: Nucleotidyl transferase; KEGG: tma:TM1033 mannose-1-phosphate guanylyltransferase. (323 aa) |
| | Fnod_0585 | PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: tte:TTE0545 Acyl-CoA dehydrogenases. (379 aa) |
| | Fnod_0586 | PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: tma:TM1835 cyclomaltodextrinase, putative. (479 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (315 aa) |
| | Fnod_0607 | TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing protein; pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; KEGG: tma:TM0272 pyruvate,orthophosphate dikinase; Belongs to the PEP-utilizing enzyme family. (881 aa) |
| | Fnod_0609 | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: tpt:Tpet_1020 3-oxoacyl-(acyl-carrier-protein) reductase. (232 aa) |
| | Fnod_0611 | TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: tpt:Tpet_0130 malonyl CoA-acyl carrier protein transacylase. (299 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (74 aa) |
| | Fnod_0639 | PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: tma:TM1878 UDP-sugar hydrolase; Belongs to the 5'-nucleotidase family. (509 aa) |
| | Fnod_0684 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: tpt:Tpet_0924 Orn/DAP/Arg decarboxylase 2; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (393 aa) |
| | Fnod_0697 | PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: tpt:Tpet_1362 FAD dependent oxidoreductase. (480 aa) |
| | Fnod_0704 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (332 aa) |
| | apgM | Phosphonopyruvate decarboxylase-related protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (401 aa) |
| | tpiA | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (243 aa) |
| | pgk | PFAM: phosphoglycerate kinase; KEGG: tma:TM0689 phosphoglycerate kinase / triose-phosphate isomerase; Belongs to the phosphoglycerate kinase family. (400 aa) |
| | Fnod_0740 | TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; KEGG: tma:TM0688 glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (332 aa) |
| | Fnod_0761 | TIGRFAM: ketose-bisphosphate aldolase; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II; KEGG: tpt:Tpet_0651 fructose-1,6-bisphosphate aldolase, class II. (330 aa) |
| | Fnod_0772 | PFAM: dihydropteroate synthase DHPS; homocysteine S-methyltransferase; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; KEGG: tma:TM0268 5-methyltetrahydrofolate S-homocysteine methyltransferase. (780 aa) |
| | Fnod_0790 | TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase; KEGG: tpt:Tpet_1664 ribose 5-phosphate isomerase B. (145 aa) |
| | plsX | Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (334 aa) |
| | Fnod_0863 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: tpt:Tpet_0905 thiamine pyrophosphate enzyme domain protein TPP-binding. (324 aa) |
| | Fnod_0864 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: tpt:Tpet_0906 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (389 aa) |
| | Fnod_0865 | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: tpt:Tpet_0907 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit. (116 aa) |
| | Fnod_0866 | TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: tpt:Tpet_0908 pyruvate/ketoisovalerate oxidoreductase, gamma subunit. (217 aa) |
| | Fnod_0867 | PFAM: glycoside hydrolase family 57; Domain of unknown function DUF1957; KEGG: tpt:Tpet_1356 domain of unknown function DUF1957; Belongs to the glycosyl hydrolase 57 family. (533 aa) |
| | pgi | PFAM: phosphoglucose isomerase (PGI); KEGG: tma:TM1385 glucose-6-phosphate isomerase; Belongs to the GPI family. (453 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (116 aa) |
| | Fnod_0882 | PFAM: mannose-6-phosphate isomerase type I; KEGG: tma:TM0736 mannose-6-phosphate isomerase. (273 aa) |
| | acpP-2 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (82 aa) |
| | plsY-2 | Protein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (205 aa) |
| | Fnod_0928 | TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; KEGG: tma:TM1693 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (250 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (370 aa) |
| | ispG | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (362 aa) |
| | surE | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (259 aa) |
| | Fnod_0958 | PFAM: phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: cbo:CBO3619 phosphoglucomutase/phosphomannomutase. (574 aa) |
| | Fnod_0968 | PFAM: aminotransferase class IV; KEGG: tpt:Tpet_0096 aminotransferase, class IV. (249 aa) |
| | Fnod_0973 | PFAM: aminotransferase class I and II; KEGG: tma:TM1255 aspartate aminotransferase. (379 aa) |
| | gcvPB | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (477 aa) |
| | gcvPA | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (441 aa) |
| | gcvT | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (430 aa) |
| | Fnod_0985 | PFAM: ribulose-phosphate 3-epimerase; KEGG: tpt:Tpet_1014 ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (212 aa) |
| | gpsA | PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein; KEGG: tpt:Tpet_0529 glycerol-3-phosphate dehydrogenase (NAD(P)(+)). (329 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (120 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (392 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (178 aa) |
| | purC | PFAM: SAICAR synthetase; KEGG: tma:TM1243 phosphoribosylaminoimidazole-succinocarboxamide synthase. (231 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (82 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (223 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (599 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (218 aa) |
| | Fnod_1147 | Glyoxylate reductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: pho:PH0597 D-3-phosphoglycerate dehydrogenase. (317 aa) |
| | Fnod_1148 | PFAM: peptidase M48 Ste24p; KEGG: dps:DP1308 similar to CAAX prenyl protease. (406 aa) |
| | Fnod_1150 | IMP cyclohydrolase; PFAM: MGS domain protein; SMART: AICARFT/IMPCHase bienzyme formylation region; KEGG: tte:TTE0592 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). (429 aa) |
| | ldh | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (310 aa) |
| | Fnod_1176 | PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: tpt:Tpet_0965 alpha amylase, catalytic region. (647 aa) |
| | Fnod_1182 | Aminotransferase class I and II; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; KEGG: cdf:CD1339 aspartate aminotransferase. (395 aa) |
| | Fnod_1210 | Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (347 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (261 aa) |
| | Fnod_1215 | PFAM: Asparaginase/glutaminase; KEGG: cbo:CBO2516 L-asparaginase. (338 aa) |
| | tal | Putative transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa) |
| | Fnod_1233 | TIGRFAM: hydroxymethylbutenyl pyrophosphate reductase; PFAM: RNA binding S1 domain protein; LytB protein; KEGG: tma:TM1445 30S ribosomal protein S1. (854 aa) |
| | Fnod_1253 | Hydroxypyruvate reductase; PFAM: MOFRL domain protein; KEGG: tma:TM1585 glycerate kinase, putative. (412 aa) |
| | trpB | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (417 aa) |
| | Fnod_1282 | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; KEGG: mka:MK0109 aspartokinase; Belongs to the aspartokinase family. (489 aa) |
| | Fnod_1311 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: tma:TM0879 ferredoxin. (82 aa) |
| | Fnod_1312 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: tma:TM0878 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit. (389 aa) |
| | Fnod_1343 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (333 aa) |
| | Fnod_1351 | PFAM: PfkB domain protein; KEGG: deb:DehaBAV1_1157 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (309 aa) |
| | Fnod_1378 | Succinate--CoA ligase (ADP-forming); PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein; KEGG: mja:MJ0210 succinyl-CoA synthetase beta chain. (355 aa) |
| | Fnod_1379 | PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: mka:MK0732 succinyl-CoA synthetase alpha subunit. (285 aa) |
| | Fnod_1415 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (365 aa) |
| | Fnod_1416 | TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: tma:TM1827 riboflavin synthase alpha chain. (197 aa) |
| | ribA | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. (396 aa) |
| | ribH | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (163 aa) |
| | Fnod_1427 | TIGRFAM: pullulanase, type I; PFAM: glycoside hydrolase family 13 domain protein; pullanase-associated protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: tpt:Tpet_0959 pullulanase, type I; Belongs to the glycosyl hydrolase 13 family. (841 aa) |
| | Fnod_1444 | KEGG: lpl:lp_3418 phosphoenolpyruvate carboxykinase (ATP). (543 aa) |
| | Fnod_1446 | Glycogen/starch/alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (818 aa) |
| | Fnod_1450 | TIGRFAM: glucose-1-phosphate thymidyltransferase; PFAM: Nucleotidyl transferase; KEGG: tpt:Tpet_0065 glucose-1-phosphate thymidyltransferase. (376 aa) |
| | Fnod_1474 | TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit; PFAM: serine dehydratase alpha chain; KEGG: tte:TTE1009 L-serine deaminase. (290 aa) |
| | Fnod_1475 | TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; PFAM: serine dehydratase beta chain; KEGG: cpf:CPF_2959 L-serine dehydratase, iron-sulfur-dependent, beta subunit. (220 aa) |
| | Fnod_1500 | PFAM: phosphatidate cytidylyltransferase; KEGG: tpt:Tpet_1386 phosphatidate cytidylyltransferase. (285 aa) |
| | Fnod_1501 | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (239 aa) |
| | glgC | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (415 aa) |
| | Fnod_1506 | TIGRFAM: glucose-1-phosphate adenylyltransferase, GlgD subunit; PFAM: Nucleotidyl transferase; KEGG: tma:TM0239 glucose-1-phosphate adenylyltransferase; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (371 aa) |
| | dxs | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (631 aa) |
| | Fnod_1529 | PFAM: Heptaprenyl diphosphate synthase component I; KEGG: tpt:Tpet_1237 heptaprenyl diphosphate synthase component I. (157 aa) |
| | Fnod_1530 | Beta-glucosidase; PFAM: glycoside hydrolase family 1; KEGG: tte:TTE0358 beta-glucosidase. (438 aa) |
| | pfp | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (422 aa) |
| | Fnod_1570 | Alpha-glucosidase; PFAM: glycoside hydrolase family 31; KEGG: tte:TTE0006 Alpha-glucosidases, family 31 of glycosyl hydrolases; Belongs to the glycosyl hydrolase 31 family. (715 aa) |
| | panC | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (280 aa) |
| | Fnod_1599 | PFAM: glycoside hydrolase family 3 domain protein; KEGG: tma:TM0025 beta-glucosidase; Belongs to the glycosyl hydrolase 3 family. (714 aa) |
| | Fnod_1648 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: tpt:Tpet_1648 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (431 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (335 aa) |
| | ispE | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (272 aa) |
| | Fnod_1671 | Phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: tpt:Tpet_1520 phosphoribosylformylglycinamidine cyclo-ligase. (308 aa) |
| | Fnod_1672 | TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; KEGG: tma:TM1250 phosphoribosylamine--glycine ligase. (410 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (203 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (435 aa) |
| | Fnod_1680 | PFAM: Transketolase domain protein; Transketolase central region; KEGG: tma:TM1762 transketolase. (623 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (431 aa) |
| | Fnod_1727 | PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: tma:TM0364 4-alpha-glucanotransferase. (454 aa) |
| | Fnod_1736 | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: tma:TM1217 glutamate synthase (NADPH) small chain. (615 aa) |
| | Fnod_1773 | TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: tpt:Tpet_0718 hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (173 aa) |
