STRINGSTRING
putA putA AIL98398.1 AIL98398.1 AIL98530.1 AIL98530.1 AIL98531.1 AIL98531.1 mmsA mmsA pip pip glnA glnA AIL99745.1 AIL99745.1 AIM00159.1 AIM00159.1 AIM00163.1 AIM00163.1 AIM00218.1 AIM00218.1 proC proC AIM00301.1 AIM00301.1 AIM00352.1 AIM00352.1 AIM00395.1 AIM00395.1 AIM00444.1 AIM00444.1 AIM00453.1 AIM00453.1 AIM00455.1 AIM00455.1 AIM00456.1 AIM00456.1 AIM00527.1 AIM00527.1 AIM00537.1 AIM00537.1 AIM00579.1 AIM00579.1 AIM00644.1 AIM00644.1 AIM00646.1 AIM00646.1 gltD gltD AIM00757.1 AIM00757.1 AIM00762.1 AIM00762.1 AIM00902.1 AIM00902.1 proB proB proA proA AIM01165.1 AIM01165.1 AIM01167.1 AIM01167.1 AIM01168.1 AIM01168.1 AIM01194.1 AIM01194.1 acs acs prpE prpE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
putATranscriptional regulator; Oxidizes proline to glutamate for use as a carbon and nitrogen source, and also functions as a transcriptional repressor of its own gene; In the N-terminal section; belongs to the proline dehydrogenase family. (1233 aa)
AIL98398.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1168 aa)
AIL98530.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
AIL98531.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (478 aa)
mmsAMethylmalonate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (498 aa)
pipProline iminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S33 family. (320 aa)
glnAForms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa)
AIL99745.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
AIM00159.1FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa)
AIM00163.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (454 aa)
AIM00218.1Gamma-aminobutyraldehyde dehydrogenase; Catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (475 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (272 aa)
AIM00301.1Catalyzes the oxidation of acetaldehyde, benzaldehyde, propionaldehyde and other aldehydes; Derived by automated computational analysis using gene prediction method: Protein Homology. (502 aa)
AIM00352.1Omega amino acid--pyruvate aminotransferase; Catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (442 aa)
AIM00395.1Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa)
AIM00444.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
AIM00453.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (477 aa)
AIM00455.1Gamma-glutamylputrescine oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
AIM00456.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (455 aa)
AIM00527.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (431 aa)
AIM00537.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (437 aa)
AIM00579.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (548 aa)
AIM00644.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1017 aa)
AIM00646.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (976 aa)
gltDGlutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (485 aa)
AIM00757.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1574 aa)
AIM00762.1Proline iminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S33 family. (296 aa)
AIM00902.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (393 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (427 aa)
AIM01165.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (510 aa)
AIM01167.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
AIM01168.1Beta alanine--pyruvate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (445 aa)
AIM01194.1NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1595 aa)
acsacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (649 aa)
prpECatalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (635 aa)
Your Current Organism:
Sinorhizobium meliloti
NCBI taxonomy Id: 382
Other names: ATCC 9930, CCUG 27879, CFBP 5561, DSM 30135, Ensifer meliloti, Ensifer sp. AC50a, Ensifer sp. AC50e, HAMBI 2148, IAM 12611, ICMP 12623, IFO 14782, JCM 20682, LMG 6133, LMG:6133, NBRC 14782, NCAIM B.01520, NRRL L-45, NZP 4027, Rhizobium meliloti, Rhizobium meliloti (megaplasmid pRME41B SYM), Rhizobium meliloti (plasmid pRmeGR4b), Rhizobium meliloti plasmid pRmeGR4b, Rhizobium sp. AC50e, S. meliloti
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