node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AIL98874.1 | hisC-2 | DU99_05435 | DU99_17635 | Histidinol-phosphate aminotransferase; Catalyzes the formation of histidinol phosphate and 2-oxoglutarate from glutamate and imidazole acetol-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Histidinol-phosphate aminotransferase; Catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.910 |
AIL98874.1 | tatA | DU99_05435 | DU99_01660 | Histidinol-phosphate aminotransferase; Catalyzes the formation of histidinol phosphate and 2-oxoglutarate from glutamate and imidazole acetol-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.912 |
AIL99070.1 | metB | DU99_06490 | DU99_00420 | O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.933 |
AIL99070.1 | metZ | DU99_06490 | DU99_02755 | O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.930 |
AIL99603.1 | AIL99607.1 | DU99_09490 | DU99_09510 | Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. | Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.713 |
AIL99603.1 | metB | DU99_09490 | DU99_00420 | Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. | Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
AIL99607.1 | AIL99603.1 | DU99_09510 | DU99_09490 | Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. | 0.713 |
AIM00228.1 | metB | DU99_12745 | DU99_00420 | Methionine gamma-lyase; Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.837 |
AIM00228.1 | metZ | DU99_12745 | DU99_02755 | Methionine gamma-lyase; Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.834 |
AIM00228.1 | tatA | DU99_12745 | DU99_01660 | Methionine gamma-lyase; Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.909 |
glyA | kbl | DU99_06255 | DU99_12965 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 2-amino-3-ketobutyrate CoA ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.915 |
glyA | tatA | DU99_06255 | DU99_01660 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.434 |
hisC-2 | AIL98874.1 | DU99_17635 | DU99_05435 | Histidinol-phosphate aminotransferase; Catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Histidinol-phosphate aminotransferase; Catalyzes the formation of histidinol phosphate and 2-oxoglutarate from glutamate and imidazole acetol-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.910 |
hisC-2 | tatA | DU99_17635 | DU99_01660 | Histidinol-phosphate aminotransferase; Catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.912 |
kbl | glyA | DU99_12965 | DU99_06255 | 2-amino-3-ketobutyrate CoA ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.915 |
metB | AIL99070.1 | DU99_00420 | DU99_06490 | Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.933 |
metB | AIL99603.1 | DU99_00420 | DU99_09490 | Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. | 0.900 |
metB | AIM00228.1 | DU99_00420 | DU99_12745 | Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine gamma-lyase; Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.837 |
metB | metZ | DU99_00420 | DU99_02755 | Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.924 |
metZ | AIL99070.1 | DU99_02755 | DU99_06490 | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.930 |