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| | gabD | Succinate-semialdehyde dehydrogenase; Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa) |
| | EM30135_1 | Catalyzes the retro-aldol cleavage of 2-keto-3-deoxy-L-rhamnonate to pyruvate and lactaldehyde; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (266 aa) |
| | AIL97865.1 | Pyridoxal 4-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa) |
| | accD | acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (304 aa) |
| | pckA | Hypothetical protein; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (536 aa) |
| | glcB | Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (723 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (306 aa) |
| | AIL97930.1 | Sarcosine oxidase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (987 aa) |
| | AIL97931.1 | Sarcosine oxidase subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (92 aa) |
| | AIL97932.1 | Sarcosine oxidase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (416 aa) |
| | AIL97934.1 | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa) |
| | AIL97935.1 | Protein GlxC; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa) |
| | AIL97936.1 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate synthase family. (442 aa) |
| | AIL97950.1 | Potassium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (445 aa) |
| | AIL97953.1 | Phosphoketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (817 aa) |
| | AIL97998.1 | 2-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa) |
| | mgsA | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (126 aa) |
| | glk | Glucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial glucokinase family. (339 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (272 aa) |
| | gpmA | Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (211 aa) |
| | AIL98017.1 | 2-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (334 aa) |
| | cysK | Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa) |
| | iolB | 5-deoxyglucuronate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa) |
| | iolE | Inosose dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa) |
| | iolD | 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (617 aa) |
| | iolC | 5-dehydro-2-deoxygluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (650 aa) |
| | AIL98220.1 | enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa) |
| | AIL98248.1 | Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (761 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (397 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transferase hexapeptide repeat family. (285 aa) |
| | pgi | Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (541 aa) |
| | argD | Acetylornithine aminotransferase; Catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (399 aa) |
| | AIL98378.1 | 3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (737 aa) |
| | AIL98379.1 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa) |
| | rhaI | Sugar isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa) |
| | folD-2 | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (299 aa) |
| | edd | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (606 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (232 aa) |
| | zwf | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (491 aa) |
| | AIL98531.1 | Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (478 aa) |
| | aceA | Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa) |
| | AIL98588.1 | Carboxymethylenebutenolidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa) |
| | AIL98603.1 | Glycolate oxidase subunit GlcD; Derived by automated computational analysis using gene prediction method: Protein Homology. (479 aa) |
| | glcE | 2-hydroxy-acid oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa) |
| | AIL98605.1 | 2-hydroxy-acid oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (454 aa) |
| | AIL98616.1 | Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa) |
| | AIL98645.1 | Trimethylamine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the trimethylamine methyltransferase family. (514 aa) |
| | AIL98712.1 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa) |
| | pdxH | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (206 aa) |
| | thrB | Serine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudomonas-type ThrB family. (326 aa) |
| | AIL98746.1 | Threonine synthase; Catalyzes the formation of L-threonine from O-phospho-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (466 aa) |
| | AIL98752.1 | 2-haloalkanoic acid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa) |
| | AIL98757.1 | Pyruvate phosphate dikinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. (898 aa) |
| | cysN | Sulfate adenylyltransferase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (498 aa) |
| | cysD | Sulfate adenylyltransferase subunit 2; With CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa) |
| | cysH | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (265 aa) |
| | AIL98793.1 | Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa) |
| | AIL98795.1 | Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa) |
| | AIL98810.1 | Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (294 aa) |
| | AIL99025.1 | Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (337 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (431 aa) |
| | mce | methylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa) |
| | accC | acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa) |
| | accB | acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (158 aa) |
| | fghA | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (277 aa) |
| | AIL99216.1 | Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (375 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (256 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (424 aa) |
| | pdhA | Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (348 aa) |
| | AIL99270.1 | Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (460 aa) |
| | AIL99271.1 | Branched-chain alpha-keto acid dehydrogenase subunit E2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (447 aa) |
| | lpdA | E3 component of alpha keto acid dehydrogenase complexes LpdC; forms a homodimer; binds one molecule of FAD monomer; catalyzes NAD+-dependent oxidation of dihydrolipoyl cofactors that are covalently linked to the E2 component; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa) |
| | cobA | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (485 aa) |
| | AIL99296.1 | Sulfite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (557 aa) |
| | AIL99305.1 | Salicylate hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa) |
| | cysE | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa) |
| | gltA | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (429 aa) |
| | AIL99387.1 | 1,2-oxophytodienoate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa) |
| | AIL99488.1 | Cysteine synthase; CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa) |
| | sseA | 3-mercaptopyruvate sulfurtransferase; Catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa) |
| | glnA | Forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa) |
| | AIL99561.1 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa) |
| | AIL99568.1 | Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa) |
| | AIL99569.1 | Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa) |
| | AIL99593.1 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa) |
| | AIL99627.1 | Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (226 aa) |
| | ligK | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa) |
| | AIL99641.1 | 4-oxalomesaconate tautomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa) |
| | AIL99663.1 | Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (404 aa) |
| | AIL99707.1 | Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (770 aa) |
| | rpiA | Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (231 aa) |
| | fumC | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (497 aa) |
| | AIL99778.1 | 5-carboxymethyl-2-hydroxymuconate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa) |
| | gndA | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (476 aa) |
| | cobA-2 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. (279 aa) |
| | AIL99836.1 | 4-oxalocrotonate tautomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 4-oxalocrotonate tautomerase family. (135 aa) |
| | AIL99844.1 | Trimethylamine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the trimethylamine methyltransferase family. (524 aa) |
| | nthB | Nitrile hydratase; NHase catalyzes the hydration of various nitrile compounds to the corresponding amides; Belongs to the nitrile hydratase subunit beta family. (219 aa) |
| | nthA | Nitrile hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa) |
| | serB | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa) |
| | pfp | Pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (404 aa) |
| | metF | 5,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (313 aa) |
| | AIM00163.1 | Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (454 aa) |
| | AIM00183.1 | Fuculose phosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa) |
| | AIM00184.1 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (345 aa) |
| | AIM00202.1 | acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (687 aa) |
| | AIM00218.1 | Gamma-aminobutyraldehyde dehydrogenase; Catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (475 aa) |
| | AIM00223.1 | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the trimethylamine methyltransferase family. (514 aa) |
| | prs | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (310 aa) |
| | AIM00301.1 | Catalyzes the oxidation of acetaldehyde, benzaldehyde, propionaldehyde and other aldehydes; Derived by automated computational analysis using gene prediction method: Protein Homology. (502 aa) |
| | fhs | Formate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the formate--tetrahydrofolate ligase family. (568 aa) |
| | AIM00355.1 | 2-dehydro-3-deoxygluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa) |
| | ureC | Urease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method: Protein Homology. (570 aa) |
| | ureB | Urease subunit beta; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem [...] (101 aa) |
| | ureA | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. (100 aa) |
| | AIM00426.1 | 2-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (325 aa) |
| | cysQ | 3'-5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (258 aa) |
| | AIM00444.1 | Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa) |
| | AIM00453.1 | Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (477 aa) |
| | AIM00456.1 | Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (455 aa) |
| | AIM00473.1 | Ferredoxin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (409 aa) |
| | AIM00476.1 | MocE; Derived by automated computational analysis using gene prediction method: Protein Homology. (109 aa) |
| | AIM00477.1 | Ferredoxin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa) |
| | AIM00496.1 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH2/MDH2 oxidoreductase family. (356 aa) |
| | pgiA | Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the archaeal-type GPI family. (214 aa) |
| | eda | 2-dehydro-3-deoxyphosphogluconate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa) |
| | AIM00505.1 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (310 aa) |
| | tkt | Transketolase; Catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transketolase family. (664 aa) |
| | AIM00527.1 | Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (431 aa) |
| | AIM00536.1 | Amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa) |
| | AIM00537.1 | Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (437 aa) |
| | hyuA | Asp/Glu/hydantoin racemase; May be involved in the asymmetric conversion of racemic 5- substituted hydantoins to the corresponding L-amino acids. Catalyzes the racemization via enolization of D- and L-5-monosubstituted hydantoins. It shows a slight preference for hydantoins with short rather than long aliphatic side chains or those with aromatic rings. (241 aa) |
| | AIM00561.1 | Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (424 aa) |
| | AIM00579.1 | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (548 aa) |
| | AIM00593.1 | 3-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (422 aa) |
| | accA | acetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa) |
| | AIM00641.1 | Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa) |
| | AIM00678.1 | 3-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (531 aa) |
| | AIM00679.1 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (392 aa) |
| | tkt-2 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (660 aa) |
| | gapA | Glyceraldehyde-3-phosphate dehydrogenase; Required for glycolysis; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa) |
| | pgk | Phosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (399 aa) |
| | AIM00715.1 | Fructose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I fructose-bisphosphate aldolase family. (341 aa) |
| | pyk | Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (479 aa) |
| | gltD | Glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (485 aa) |
| | AIM00757.1 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1574 aa) |
| | AIM00758.1 | Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (348 aa) |
| | AIM00776.1 | Sulfite oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa) |
| | AIM00791.1 | Phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (542 aa) |
| | AIM00795.1 | Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa) |
| | AIM00828.1 | Keto-deoxy-phosphogluconate aldolase; Catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (485 aa) |
| | lpdA-2 | Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa) |
| | maiA | Maleylacetoacetate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa) |
| | AIM00880.1 | 2-keto-4-pentenoate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa) |
| | hmgA | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (453 aa) |
| | fdsD | Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (77 aa) |
| | AIM00946.1 | Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (959 aa) |
| | AIM00948.1 | Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (518 aa) |
| | AIM00949.1 | Catalyzes the oxidation of formate to carbon dioxide and hydrogen using NAD or NADP as the acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa) |
| | fsa | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa) |
| | AIM00986.1 | Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa) |
| | odhB | Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (417 aa) |
| | sucA | SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. (998 aa) |
| | sucD | succinate--CoA ligase; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (300 aa) |
| | sucC | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (398 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa) |
| | AIM01007.1 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (259 aa) |
| | AIM01008.1 | Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (613 aa) |
| | sdhD | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (126 aa) |
| | sdhC | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (130 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (309 aa) |
| | AIM01018.1 | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (235 aa) |
| | AIM01060.1 | Aldose epimerase; Converts alpha-aldose to the beta-anomer. (338 aa) |
| | AIM01079.1 | Sugar kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa) |
| | acnA | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (896 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (301 aa) |
| | AIM01140.1 | acetoacetyl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa) |
| | AIM01141.1 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa) |
| | pyc | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1152 aa) |
| | AIM01165.1 | Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (510 aa) |
| | AIM01169.1 | Hydroxypyruvate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (455 aa) |
| | AIM01179.1 | CoA-transferase; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family. (540 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa) |
| | AIM01194.1 | NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1595 aa) |
| | acs | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (649 aa) |
