(29 nodes) Clathrin coat, and Eps15 homology domain network (Cajanus cajan)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KK1_046781	Putative clathrin assembly protein At4g40080 family. (335 aa)
	KK1_045397	AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family. (438 aa)
	KK1_043851	Putative serine/threonine-protein kinase DDB-G0280111. (677 aa)
	KK1_041909	Extracellular ribonuclease. (386 aa)
	KK1_040713	Epsin-2. (291 aa)
	KK1_037557	Putative calcium-binding protein C800.10c family. (1081 aa)
	KK1_036926	Putative clathrin assembly protein At1g05020 family. (624 aa)
	KK1_032710	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1674 aa)
	KK1_031930	AP-2 complex subunit alpha; Subunit of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. (1020 aa)
	KK1_030801	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1697 aa)
	KK1_025384	AP-1 complex subunit beta-1. (844 aa)
	KK1_024675	Adaptin ear-binding coat-associated protein 1. (288 aa)
	KK1_000937	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family. (1034 aa)
	KK1_002743	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1701 aa)
	KK1_003001	Rhodanese domain-containing protein. (385 aa)
	KK1_003724	MHD domain-containing protein. (629 aa)
	KK1_013953	Epsin-3. (325 aa)
	KK1_023033	Uncharacterized protein. (416 aa)
	KK1_019479	Putative calcium-binding protein C800.10c family. (1058 aa)
	KK1_019591	Epsin-3. (272 aa)
	KK1_013380	AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family. (438 aa)
	KK1_013381	AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family. (462 aa)
	KK1_021673	Beta-adaptin-like protein; Subunit of clathrin-associated adaptor protein complex that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (934 aa)
	KK1_021805	Epsin-2. (331 aa)
	KK1_005682	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1707 aa)
	KK1_006830	Uncharacterized protein At1g03900 family. (281 aa)
	KK1_007215	Activating signal cointegrator 1. (388 aa)
	KK1_008249	Epsin-2. (777 aa)
	KK1_020134	Uncharacterized protein. (172 aa)

Your Current Organism:

Cajanus cajan

NCBI taxonomy Id: 3821
Other names: C. cajan, Cajanus cajan (L.) Millsp., pigeon pea

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KK1_000937	KK1_002743	A0A151SIW2	A0A151SP40	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.746
KK1_000937	KK1_003001	A0A151SIW2	A0A151SPJ4	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	Rhodanese domain-containing protein.	0.759
KK1_000937	KK1_003724	A0A151SIW2	A0A151SRL4	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	MHD domain-containing protein.	0.664
KK1_000937	KK1_005682	A0A151SIW2	A0A151U1D4	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.746
KK1_000937	KK1_006830	A0A151SIW2	A0A151U4B0	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	Uncharacterized protein At1g03900 family.	0.669
KK1_000937	KK1_007215	A0A151SIW2	A0A151U5M4	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	Activating signal cointegrator 1.	0.547
KK1_000937	KK1_008249	A0A151SIW2	A0A151U890	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	Epsin-2.	0.491
KK1_000937	KK1_013380	A0A151SIW2	A0A151TJ34	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family.	0.839
KK1_000937	KK1_013381	A0A151SIW2	A0A151TJ41	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family.	0.839
KK1_000937	KK1_013953	A0A151SIW2	A0A151SUR4	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	Epsin-3.	0.483
KK1_000937	KK1_019479	A0A151SIW2	A0A151TCV2	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	Putative calcium-binding protein C800.10c family.	0.651
KK1_000937	KK1_019591	A0A151SIW2	A0A151TD61	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	Epsin-3.	0.483
KK1_000937	KK1_021673	A0A151SIW2	A0A151TM29	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	Beta-adaptin-like protein; Subunit of clathrin-associated adaptor protein complex that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.921
KK1_000937	KK1_021805	A0A151SIW2	A0A151TMB4	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	Epsin-2.	0.483
KK1_000937	KK1_023033	A0A151SIW2	A0A151T0P8	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	Uncharacterized protein.	0.483
KK1_000937	KK1_024675	A0A151SIW2	A0A151SEN7	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	Adaptin ear-binding coat-associated protein 1.	0.669
KK1_000937	KK1_025384	A0A151SIW2	A0A151SCZ4	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	AP-1 complex subunit beta-1.	0.921
KK1_000937	KK1_030801	A0A151SIW2	A0A151RYB2	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.746
KK1_000937	KK1_031930	A0A151SIW2	A0A151RV94	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	AP-2 complex subunit alpha; Subunit of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome.	0.485
KK1_000937	KK1_032710	A0A151SIW2	A0A151RT55	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.746