STRINGSTRING
LOC101491004 LOC101491004 LOC101488705 LOC101488705 LOC101502711 LOC101502711 LOC101512677 LOC101512677 LOC101502490 LOC101502490 LOC101500686 LOC101500686 LOC101499469 LOC101499469 LOC101515563 LOC101515563 LOC101502334 LOC101502334 LOC101490846 LOC101490846 LOC101513194 LOC101513194 LOC101509971 LOC101509971 LOC101514286 LOC101514286 LOC101491265 LOC101491265 LOC101514931 LOC101514931 LOC101491782 LOC101491782 LOC101490074 LOC101490074 LOC101508463 LOC101508463 LOC101504587 LOC101504587 LOC101491330 LOC101491330 LOC101498700 LOC101498700 LOC101503142 LOC101503142 LOC101505725 LOC101505725 LOC101510962 LOC101510962 LOC101511036 LOC101511036 LOC101511040 LOC101511040 LOC101512477 LOC101512477 LOC101514366 LOC101514366 LOC101505566 LOC101505566 LOC101512205 LOC101512205 LOC101512446 LOC101512446 LOC101502989 LOC101502989 LOC101492775 LOC101492775 LOC101498078 LOC101498078 LOC101503172 LOC101503172 LOC101506947 LOC101506947
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101491004Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (628 aa)
LOC101488705DNA polymerase. (1532 aa)
LOC101502711DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (210 aa)
LOC101512677Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (617 aa)
LOC101502490DNA helicase; Belongs to the MCM family. (732 aa)
LOC101500686DNA helicase; Belongs to the MCM family. (935 aa)
LOC101499469DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (720 aa)
LOC101515563FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (641 aa)
LOC101502334Origin of replication complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (420 aa)
LOC101490846DNA helicase; Belongs to the MCM family. (839 aa)
LOC101513194Replication factor C subunit 1. (997 aa)
LOC101509971DNA ligase. (774 aa)
LOC101514286DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2212 aa)
LOC101491265DNA helicase; Belongs to the MCM family. (775 aa)
LOC101514931DNA helicase; Belongs to the MCM family. (851 aa)
LOC101491782Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (893 aa)
LOC101490074DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (616 aa)
LOC101508463Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (266 aa)
LOC101504587Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (409 aa)
LOC101491330DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (227 aa)
LOC101498700DNA ligase. (1362 aa)
LOC101503142FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (643 aa)
LOC101505725DNA ligase. (693 aa)
LOC101510962DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (227 aa)
LOC101511036DNA primase; Belongs to the eukaryotic-type primase small subunit family. (460 aa)
LOC101511040Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (814 aa)
LOC101512477Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (917 aa)
LOC101514366DNA primase; Belongs to the eukaryotic-type primase small subunit family. (512 aa)
LOC101505566Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (810 aa)
LOC101512205DNA replication complex GINS protein PSF1 isoform X1. (208 aa)
LOC101512446DNA ligase. (1172 aa)
LOC101502989DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (471 aa)
LOC101492775DNA polymerase. (1087 aa)
LOC101498078DNA replication complex GINS protein PSF3-like. (185 aa)
LOC101503172DNA polymerase. (1912 aa)
LOC101506947DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (529 aa)
Your Current Organism:
Cicer arietinum
NCBI taxonomy Id: 3827
Other names: C. arietinum, Cicer arietinum L., chickpea, garbanzo
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