(6 nodes) IMP dehydrogenase activity, and GMP biosynthesis network (Streptomyces pristinaespiralis)

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Your Input:
	guaA	GMP synthase; Catalyzes the synthesis of GMP from XMP. (531 aa)
	SPRI_3115	Inosine-5-monophosphate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (374 aa)
	guaB	Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (499 aa)
	purA	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (427 aa)
	SPRI_6102	Inosine-5-monophosphate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (480 aa)
	SPRI_6278	Adenylosuccinate lyase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (480 aa)

Your Current Organism:

Streptomyces pristinaespiralis

NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SPRI_3115	SPRI_6102	SPRI_3115	SPRI_6102	Inosine-5-monophosphate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Inosine-5-monophosphate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.907
SPRI_3115	SPRI_6278	SPRI_3115	SPRI_6278	Inosine-5-monophosphate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Adenylosuccinate lyase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.797
SPRI_3115	guaA	SPRI_3115	SPRI_3104	Inosine-5-monophosphate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.997
SPRI_3115	guaB	SPRI_3115	SPRI_3116	Inosine-5-monophosphate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.986
SPRI_3115	purA	SPRI_3115	SPRI_3580	Inosine-5-monophosphate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.986
SPRI_6102	SPRI_3115	SPRI_6102	SPRI_3115	Inosine-5-monophosphate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Inosine-5-monophosphate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.907
SPRI_6102	SPRI_6278	SPRI_6102	SPRI_6278	Inosine-5-monophosphate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Adenylosuccinate lyase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.818
SPRI_6102	guaA	SPRI_6102	SPRI_3104	Inosine-5-monophosphate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.998
SPRI_6102	guaB	SPRI_6102	SPRI_3116	Inosine-5-monophosphate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.958
SPRI_6102	purA	SPRI_6102	SPRI_3580	Inosine-5-monophosphate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.981
SPRI_6278	SPRI_3115	SPRI_6278	SPRI_3115	Adenylosuccinate lyase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	Inosine-5-monophosphate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.797
SPRI_6278	SPRI_6102	SPRI_6278	SPRI_6102	Adenylosuccinate lyase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	Inosine-5-monophosphate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.818
SPRI_6278	guaA	SPRI_6278	SPRI_3104	Adenylosuccinate lyase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.929
SPRI_6278	guaB	SPRI_6278	SPRI_3116	Adenylosuccinate lyase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.919
SPRI_6278	purA	SPRI_6278	SPRI_3580	Adenylosuccinate lyase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.996
guaA	SPRI_3115	SPRI_3104	SPRI_3115	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Inosine-5-monophosphate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.997
guaA	SPRI_6102	SPRI_3104	SPRI_6102	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Inosine-5-monophosphate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.998
guaA	SPRI_6278	SPRI_3104	SPRI_6278	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Adenylosuccinate lyase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.929
guaA	guaB	SPRI_3104	SPRI_3116	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.999
guaA	purA	SPRI_3104	SPRI_3580	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.974